DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and Ugt303A1

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001262470.1	Gene:	Ugt303A1 / 53503	FlyBaseID:	FBgn0040252	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	175/516 - (33%)
Similarity:	281/516 - (54%)	Gaps:	41/516 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LILGLLCS-----------LGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQ 59
            |:.||||.           ..|:.|.:||::.            ...:.||:.||.:|::|....
  Fly    15 LLFGLLCPKLTNAENILAVFSYTFGSSYLLIT------------PFLRNLVQRGHQLTLISAVTI 67

  Fly    60 KKPIPGYTDVSVPNVIEVM--------GGDIGALWASIQKTYTQNLIDHYQMGFRITRGLFEDSN 116
            ...|.|...:.||.:..:|        ..|: ..|     |..|.|.:::   :..::.:.||..
  Fly    68 MPHIEGVHHIRVPKLDMLMKILLDFEYDTDL-TKW-----TEAQFLSEYF---YNCSKFVLEDPG 123

  Fly   117 FQDFLK-SNQSFDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIM 180
            .|:.|: ::..:..||.|..:|||.||.::||||||:|:|..|....|..:||:.||:.:.|...
  Fly   124 VQELLRNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYGSSWNIDFLVGNSAPSVYEPMSA 188

  Fly   181 LPFNDHMSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFPGNKRCFYKMRRNASLVLINQHV 245
            |.:...::|.|:..|:.::..||::..:.:||.|..|||:.|||.....:.:||..||||||||.
  Fly   189 LGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFPGATTSIHDLRRRFSLVLINQHF 253

  Fly   246 SLSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPSKVQEIL 310
            ::...|.:.||::||.|||:|.|..||..::::.::|:|||.||||||..|....|||.....:.
  Fly   254 TMGRVRSNVPNIVEVAGMHLDEKPYPLDAELKKILDEAEHGVIYFSMGLQLLDHWLPPGMRASMS 318

  Fly   311 KALGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPV 375
            .|...|||:|:||.:...:.|:..||:...||||..||.||.:..|:||.|:||..||:::|.|:
  Fly   319 DAFAQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPL 383

  Fly   376 IGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQT 440
            :.:|:|.|||.|....|:.|....||||.|...|...|||.:....||.:..:.:|.|:.||..:
  Fly   384 LCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMS 448

  Fly   441 PIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLPITIYKLL 501
            .::.||:|.|::.||:||.:::.|.|.::..||:||||:.::|..:.|..|::....:||:
  Fly   449 AMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGWKLV 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	170/493 (34%)
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	155/459 (34%)
Ugt303A1	NP_001262470.1	UDPGT	39..507	CDD:278624	167/488 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445615
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	11	10.800