DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and Ugt303B1

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	512	Identity:	153/512 - (29%)
Similarity:	270/512 - (52%)	Gaps:	10/512 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TLILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTDV 69
            ||.|.||.....:...|.|.:......|.|.|...|.:.|...||.:|:::.......|.|...:
  Fly     9 TLSLCLLLQHDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIGMPNDIEGVRHI 73

  Fly    70 SV----PNVIEVMGGDIGALWASIQKTYTQNLIDHYQMGFRITRGLFEDSNFQDFL-KSNQSFDA 129
            .|    ..:.|::..| ..|...|.| :|::.:....: |..:..:..|...|..| ..::|||.
  Fly    74 RVAQLNERIKEMLESD-QVLDFMINK-WTESALTAKAL-FNASNDILSDPGVQRMLHDKSESFDL 135

  Fly   130 IICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIMLPFNDHMSLYERLL 194
            ||.|....||.|||.|.:||.|:||::........::.|:|||:.:.|...:.|:...||:.|:.
  Fly   136 IIMEPSSLDALYGLVEFYNATLMGLSSIRINWHTYELAGNPAPSIYEPISPVGFSLETSLFSRVY 200

  Fly   195 NVAFLGYERVLLDYYFL-PTQEKLYKEFFPGNKRCFYKMRRNASLVLINQHVSLSFPRPHSPNMI 258
            |...: .|..|::|..| |.|..|:::||..:.:...::|...||:|||.|.|:...|.::||:|
  Fly   201 NWIHI-MEEKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGKVRANAPNII 264

  Fly   259 EVGGMHIDGKWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWK 323
            ||||:|:.....|..|::::|:::::||.||||||:::..|.||.:..:.:|:....|.:.::||
  Fly   265 EVGGLHLSEPPEPSDEELQKFLDKADHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWK 329

  Fly   324 FELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNM 388
            .||..:|:|.:|||:.:..||..||.||.:..|:|:||:||..|::....|::|||:|.|||.||
  Fly   330 SELLYMPDKSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNM 394

  Fly   389 AHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVT 453
            ...:.:|...::|..:||.....:.|:.:.:..||....:.||..::|:..:|::.|::|.|:..
  Fly   395 RWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYAL 459

  Fly   454 RHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLPITIYKLLKKLLLKGER 510
            |::....::...:.:...:|:.:|.:|...:...|:...|...:|.|..|..::..|
  Fly   460 RNRNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLVYTLFLKYRIRLRR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	146/480 (30%)
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	139/444 (31%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	142/473 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445624
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	11	10.800