DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and Ugt316A1

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001287111.1	Gene:	Ugt316A1 / 40079	FlyBaseID:	FBgn0036842	Length:	636	Species:	Drosophila melanogaster

Alignment Length:	528	Identity:	157/528 - (29%)
Similarity:	269/528 - (50%)	Gaps:	35/528 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRTFTLILG-LLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKA--GHTITVVSVFPQKKP 62
            |:...:.|| |||  |...|.|.|.|..|..:||:..|..|.:.||::  .|::|::|....::.
  Fly     1 MQILQVFLGTLLC--GIVLGANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQEG 63

  Fly    63 IPGYTDVSVPNVIEVMGGDIGALWASIQKTYTQNLIDHYQMGFRITRGLF----------EDSNF 117
            :    |..:|.:.|:....:...|..:..::....:....:..|.||.::          .|...
  Fly    64 V----DAEIPKIRELRIEGLRENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVDILLSDPQV 124

  Fly   118 QDFLKSNQSFDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIMLP 182
            :..|.|.:.||.:|.:.|.:||..|||.::..|.:.::..|..:::.:|.|:|..:|..|...||
  Fly   125 RKLLTSGEKFDLLIVDLFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLDPSNFLP 189

  Fly   183 FNDHMSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFF-------PGNKRCFYKMRRNASLVL 240
            |.:.|:..:|:||.....:||:..:::.|.:|:.:|...|       |    .:..:.:|.||.|
  Fly   190 FTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFELLVKELP----LYRDLTKNLSLAL 250

  Fly   241 INQHVSLSFPRPHSPNMIEVGGMHIDG-KWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPS 304
            ||.|..|.:||.:.|||:||||:|:.. ..:.||:.:..|:..:..|.||||:|::::|..||..
  Fly   251 INSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESAPSGVIYFSLGADVETAQLPQE 315

  Fly   305 KVQEILKALGGLKQ-RVLWKFELDNLPNK---PENVYISDWFPQTDILAHPKIMAFVTHGGMLST 365
            |:..||...|.||: ..|.|:|.:....:   ||||.|:||:||..||.||::..|::..|.||.
  Fly   316 KLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSV 380

  Fly   366 TESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGI 430
            .|||...|||:.:||.::|.......:::|..:.:.:.:|........|.::|...||.:.:..:
  Fly   381 WESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQL 445

  Fly   431 SFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLPI 495
            ..|...:..||:..|:..::.:....||.:|||.|..||:|:...|||||||.|....:|.:..:
  Fly   446 KERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWRAEGVDVLLIIAVGFFGILTIPFL 510

  Fly   496 TIYKLLKK 503
            .|..:|:|
  Fly   511 AICFILRK 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	148/503 (29%)
Ugt316A1	NP_001287111.1	egt	1..480	CDD:223071	141/488 (29%)
Ugt316A1	NP_001287111.1	MGT	39..448	CDD:273616	117/416 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445638
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	8	7.850