DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and Ugt317A1

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	538	Identity:	144/538 - (26%)
Similarity:	236/538 - (43%)	Gaps:	50/538 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ILGLLCSLG-YSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYT--- 67
            ||||  :|| .|.....|::.......||.|...|...|....|||.|            ||
  Fly    13 ILGL--ALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEV------------YTGHG 63

  Fly    68 -DVSVPNVIEVMGGDIGALWASIQKTYTQ--NLID------------HYQMGFRITRGLFEDSNF 117
             ..|:.||.|.:..:. ..|:.:||....  ||.|            ...:|.|...........
  Fly    64 LGESLDNVTETVTAEF-PFWSELQKQAAPKGNLADLGLLPIEKLRQSLASVGARALDHFLAQEPI 127

  Fly   118 QDFLKSNQ---SFDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHI 179
            |..||.:.   .||.|:.:.||.:|...|......|::|:.:.....::..:..:..||:..|..
  Fly   128 QKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEALVPAACSPID 192

  Fly   180 MLPFNDHMSLYERLLNV--AFLGYERVLLDYYFLPTQEKLYKEFFPGNKRCFYKMRRNASLVLIN 242
            .......||...||.|:  .....::.:.|:|  ..||:|..::|..............|::|:|
  Fly   193 FERDQPEMSFSVRLGNIRTCIARRKQFIKDHY--GGQEQLVTKYFQLQSSIPELQASQLSVLLLN 255

  Fly   243 QHVSLSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPSKVQ 307
            .||.|..|:.....:|..||:||.|. ..||..::||:.|:..||||..:|:......||..|:.
  Fly   256 SHVPLITPKVSIQQIIPAGGLHIRGP-KELPWNVKRFLEEARPGAIYVQLGNEQACGQLPKEKLD 319

  Fly   308 EILKALGGLKQRVLWK-FELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYH 371
            .:.......||.::|. .::..|...|:||.|....||.||||||::.||:|:|.:|:..|.|..
  Fly   320 TLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTNGDLLNLQEGIMR 384

  Fly   372 AKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRD 436
            ..|::|||:|..:..||..|.:.|.|:.|:...:.......|::|:..|..:...::.:|..:||
  Fly   385 NVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAVDRLLLESHFQLTIRDVSLEFRD 449

  Fly   437 QQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLI---IFVVMVLLLIVLPITIY 498
            :....:.:|::||.:|.||:|.:.|::....::..|.|..|:.:.   |..::|.||:.|....:
  Fly   450 RPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLFVFYAGIATLVVSLLVALSFGGF 514

  Fly   499 KLLKKLLLKGERTQSTKV 516
            .:..    |...::||||
  Fly   515 YIWN----KKNNSKSTKV 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	134/497 (27%)
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	125/470 (27%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	132/504 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970