DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and Ugt37A1

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_523607.2	Gene:	Ugt37A1 / 35307	FlyBaseID:	FBgn0026756	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	168/531 - (31%)
Similarity:	262/531 - (49%)	Gaps:	34/531 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FTLILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTD 68
            |.::|.|...:..:.|.|.|.:..|...||..:..::||.|.:.||.:|||:|............
  Fly     9 FVIVLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTITHKNINL 73

  Fly    69 VSVPNVIEVMGGDIGALWASIQKTYTQNLIDHYQMG------FRITRGLFEDSNFQD-FLKSNQS 126
            |:||...|.:......:.|..:.|.:...|....|.      .|....:.:|...:: :|..:..
  Fly    74 VTVPMTKEEIKQRSETIGAKQKNTSSNRFISILNMSGQMDSMLRKMADVLKDQRVKELYLNKDNH 138

  Fly   127 FDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIMLPFNDHMSLYE 191
            ||.:|...|.||...|.|...|||::.||.......:..::|:       ||..:.....|:..:
  Fly   139 FDLVISGYFMNDYQLGFARKVNAPVVVLAPSPPSQMLNSLIGN-------PHDKVEKEKGMTFGQ 196

  Fly   192 RLLNVAFLGYERVLLDYYFL----PTQEKLYKEFFPGNKRC--FYKMRRNASLVLINQHVSLSFP 250
            ||.:     |...||...||    ....:.|.|.|..:...  :..:.||.|||....|.:...|
  Fly   197 RLDS-----YISSLLYGIFLRQIDQRNRQYYNEIFGDDPTMPEYTDILRNTSLVFFCSHAASEGP 256

  Fly   251 -RPHSPNMIEVGGMHIDGKWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPSKVQEILKALG 314
             ||..|..||:||:.|..|.:|||:.:|:|:..:.||||..|:|||::...:....|::|...|.
  Fly   257 IRPSVPAAIEIGGIQIKDKPDPLPKNLEKFLGNATHGAILLSLGSNVQGSHIKADTVKKIFSVLS 321

  Fly   315 GLKQRVLWKF-ELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGL 378
            .|||||:||: :||..|.|.:|:..|.|.||.||||||.:..|:.|.|....:|:.||.||::.|
  Fly   322 NLKQRVIWKWDDLDKTPGKSDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSL 386

  Fly   379 PIFSDQFFNMAHA-EQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPI 442
            |:|.||..| ||| .::|:|:.|...||....||.|:..|.|.|.|::.|...|..|||:..:..
  Fly   387 PVFGDQPGN-AHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLYRDRPASAR 450

  Fly   443 ENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLPITIYKLLKKLLLK 507
            |:.|:|.|:|.||.|||:|:|....:::...:|:|:..:|..:.:.||::|...:....::|
  Fly   451 ESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIYALIGAISIGLLLMLKKVVQITCRRL--- 512

  Fly   508 GERTQSTKVKR 518
              ||:..|||:
  Fly   513 --RTKLNKVKK 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	158/491 (32%)
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	142/443 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445729
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	8	7.950