DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and Ugt301D1

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	522	Identity:	169/522 - (32%)
Similarity:	269/522 - (51%)	Gaps:	32/522 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTDVS 70
            :::.|:..|.:.:|...|.:......||:.........|::.||.:|.|:..|.|.|....|::.
  Fly    11 MLIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEII 75

  Fly    71 VPNVIEVMGGDIGALWASIQKTYTQ-------------NLIDHYQMGFRITRGLFEDSNFQDFLK 122
            :....:            |.|.:.:             ||...:.:|...|...|:|...:..::
  Fly    76 ISPSFD------------IPKHFPKENIFSMQFVSDFNNLELWWTIGLMTTEHAFKDPKVKKLIE 128

  Fly   123 S-NQSFDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIMLPFNDH 186
            | :..:|.:|.|.|:::|.....:.||.|::.:.|.|....|...:|...|.|.:||::|...|.
  Fly   129 SKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHTDR 193

  Fly   187 MSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFPGNKR----CFYKMRRNASLVLINQHVSL 247
            |:..:|..|.....|:.|:..:.:||..:||.:::|.|:..    ....:.||.||||||.|.|:
  Fly   194 MTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINAHRSI 258

  Fly   248 SFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPSKVQEILKA 312
            ..|||..|.:|:|||.||. |...||..::.|::.:.:|.|||||||.:|:.|||..|...||||
  Fly   259 DLPRPSMPGLIDVGGAHIQ-KPKQLPTDLQNFLDNATYGVIYFSMGSYVKSTDLPQEKTALILKA 322

  Fly   313 LGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIG 377
            .|.|||:|:||||.|::.:.|.||.|..|.||.||||||.:..|:||||:..|.|.||...|::.
  Fly   323 FGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLC 387

  Fly   378 LPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPI 442
            :|::.||..|...:.:.||...|.|..|...:..:.||.:.::|.|.:....:|.|:||....|:
  Fly   388 VPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPL 452

  Fly   443 ENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLPITIYKLLKKLLLK 507
            :.|.:|:|::.||:||.:|||....:...||..:|||..: ::...|.|.||..:.:.:.|..||
  Fly   453 DEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCL-LLGAFLAIWLPWRMIRRVHKWWLK 516

  Fly   508 GE 509
            ||
  Fly   517 GE 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	159/491 (32%)
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	155/483 (32%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	151/458 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.860