DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302K1 and Ugt2b37

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001007265.4	Gene:	Ugt2b37 / 29623	RGDID:	3937	Length:	530	Species:	Rattus norvegicus

Alignment Length:	515	Identity:	147/515 - (28%)
Similarity:	236/515 - (45%)	Gaps:	69/515 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 SHFNVGHALAKGLVKAGHTITVVS------VFPQKKP------IPGYTDVSVPNVIEVMGGDIGA 84
            ||:.....:...||:.||.:||:.      :.|:|.|      .|  |.||...:.:.....:.|
  Rat    34 SHWMNIKTILDELVQRGHEVTVLKPSAYYVLDPKKSPDLKFETFP--TSVSKDELEKYFIKLVDA 96

  Fly    85 LWASIQK-------TYTQNLIDHYQMGFRITRGLFED--SNFQDFLKSNQS-FDAIICETFYNDA 139
            ....:|:       ...||::|.:...:   ..:.:|  ||.|...|..:| ||.::.:..   |
  Rat    97 WTYELQRDTCLSFSPLLQNMMDEFSDYY---LSVCKDAVSNKQLMAKLQESKFDVLLSDPV---A 155

  Fly   140 HYG--LAEHFNAPLIGLATGGGLTFITDMVGSPA------------PASFVPHIMLPFNDHMSLY 190
            ..|  :||..:.|           |:..:..||.            |.|:||.|:......|:..
  Rat   156 ACGELIAEVLHIP-----------FLYSLRASPGHKIEKSSGRFILPPSYVPVILSGLGGQMTFI 209

  Fly   191 ERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFP---GNKRCFYKMRRNASLVLINQHVSLSFPRP 252
            :|:.|:..:.|    .|::|.....|.:..|:.   |......:....|.:.||..:..|.||.|
  Rat   210 DRVKNMICMLY----FDFWFHMFNAKNWDPFYTEILGRPTTLAETMGKAEMWLIRSYWDLEFPHP 270

  Fly   253 HSPNMIEVGGMHIDGKWNPLPEKIERFINES-EHGAIYFSMGSNLKTKDLPPSKVQEILKALGGL 316
            ..||:..:||:..... .|||:.||.|:..| |||.:.||:||.:.:  :...|...:..||..:
  Rat   271 TLPNVDYIGGLQCKPA-KPLPKDIEDFVQSSGEHGVVVFSLGSMVSS--MTEEKANAVAWALAQI 332

  Fly   317 KQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIF 381
            .|:|||||:.........|..:..|.||.|:|.|||..|||||||.....|:|||..|:||:|:|
  Rat   333 PQKVLWKFDGKIPATLGPNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPMF 397

  Fly   382 SDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENAI 446
            .:|..|:||....|..:.|:.:|::..:...|::.:.:.|.|.|....:|..:.||...|::.||
  Rat   398 GEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEVINNPFYKKNAMWLSTIHHDQPMKPLDKAI 462

  Fly   447 YWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDV---LLIIFVVMVLLLIVLPITIYKLLKK 503
            :|:|:|.||:.|.:|:.....|.|:|||::||   ||....|:..|.:...:.||:...|
  Rat   463 FWIEYVMRHKRAKHLRPLGHNLPWYQYHSLDVIGFLLACLAVIAALAVKCFLFIYRFFAK 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	140/490 (29%)
Ugt2b37	NP_001007265.4	UDPGT	24..527	CDD:278624	147/515 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1959
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2882
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm9018
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.760