Protein Alignment Ugt302K1 and Ugt1a2

DIOPT Version :9

• Sequence 1: NP_001287281.1
• Gene: Ugt302K1 / 53502
• FlyBaseID: FBgn0040251
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 558
• Identity: 151/558 - (27%)
• Similarity: 263/558 - (47%)
• Gaps: 76/558 - (13%)

  Fly     1 MRTFTLILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPG 65
            :|..:.:|.|||:|.::.|.. ::||...|....:: ..:.:.|...||...|::
Mouse     9 LRGISGLLLLLCALPWAEGAK-VLVLPMEGSQWLSM-RDVVRELHARGHQTVVLA---------- 61

  Fly    66 YTDVSVPNVIEVMGGDIGAL----WASIQKTYTQNLIDHYQMGFR---ITRGLFEDS----NFQD 119
             ::|:|    .:.|.|...|    :...::.|.|.::...:..|:   ..:..||.:    ||.|
Mouse    62 -SEVTV----HIKGEDFFTLKTYAFPYTKEEYQQEILSDIEKTFKTQHFVKAFFETTASIRNFFD 121

  Fly   120 FLKS---------------NQS-FDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVG 168
            ...:               |.| ||.|:.:..: .....||::...|.:.:..........:...
Mouse   122 LYSNSCIALLHNKMLIQQLNSSFFDVILTDPIF-PCGAVLAKYLQIPAVFILRSLSCGIEYEATQ 185

  Fly   169 SPAPASFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDY---YFLPTQEKLYKEFFPGNKRCFY 230
            .|.|:|::|:::...:|||...:|:.|:.:.    ::|.|   ..:...|.|..|.
Mouse   186 CPNPSSYIPNLLTRLSDHMDFLQRVQNMLYY----LVLKYICRLSITPYESLASEL--------- 237

  Fly   231 KMRRNASLVLINQHVS---------LSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINES-EH 285
             ::|..|||.:..|.|         |.:|||..|||:.:||::...| .||.::.|.::|.| ||
Mouse   238 -LQREVSLVEVLSHASVWLFRGDFVLDYPRPIMPNMVFIGGINCVTK-KPLSQEFEAYVNASGEH 300

  Fly   286 GAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDILAH 350
            |.:.||:||  ...::|..|..||.:|||.:.|.|||::......|..:|..:..|.||.|:|.|
Mouse   301 GIVVFSLGS--MVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGH 363

  Fly   351 PKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIE 415
            ||..||:||.|.....|.|.:..|::.:|:|.||..|....|..|.|:.|:...:.|.:...|::
Mouse   364 PKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALK 428

  Fly   416 RITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVL- 479
            .:.:..||.:.:..:|..::|:...|::.|::|||:|.||:||.:|:.||..|.|:|||::||:
Mouse   429 TVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIG 493

  Fly   480 LIIFVVMVLLLIVLPITIYKLLKKLLLKGERTQSTKVK 517
            .::.:|:.::.||.....|...|....||...:|.|.|
Mouse   494 FLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	141/519 (27%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	141/530 (27%)
		Glycosyltransferase_GTB_type	43..>175	CDD:299143	25/148 (17%)
		egt	<261..505	CDD:223071	87/246 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840640
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.690