DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and ugt-3

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_506203.2	Gene:	ugt-3 / 191174	WormBaseID:	WBGene00013903	Length:	529	Species:	Caenorhabditis elegans

Alignment Length:	539	Identity:	139/539 - (25%)
Similarity:	246/539 - (45%)	Gaps:	54/539 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTIT-----VVSVFPQKKPIPGYTDV 69
            ||.....:.|:|||::....|.||......:|..|..|||.:|     :...:..||.:..
Worm     6 LLAFFPVAFGFNYLIISPVFGYSHMKFMGRIADILADAGHNVTLFQPIIYDYYAHKKIVKN---- 66

  Fly    70 SVPNVIEVMGGDI------GALWASIQKTY-----TQNLIDH--------YQMGFRITRGLFEDS 115
              || |||:..::      .|..||:.|.:     ::|.|..        |:....|.|.:..|.
Worm    67 --PN-IEVINYEVDEEEKAAASEASVFKFFWKAKGSKNPISSAKITSEKLYKEFEHICRKMLLDK 128

  Fly   116 NFQDFLKSNQSFDAIICETF-YNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHI 179
            ....::.| ::||:.|.|.| :...:.|......:| |.|.:|......:..||.|.|.:::|..
Worm   129 ELHRWILS-KNFDSHISEAFDFCGLYLGDFLKLKSP-IPLYSGVRCGAASYAVGEPIPLNYLPTE 191

  Fly   180 MLPFNDHMSLYERLLNVAFL-GYERVLLDYYFLPTQEKLYKEFF---PGNKRCFYKMRRNASLVL 240
            ...:....|..:||.::..| ||.     :.|....:|.|.:.:   .||.|.:.::.::::..|
Worm   192 GSNYGKKSSAIDRLSDMLGLTGYH-----FQFGILFDKQYDQAYRLTGGNVRTWQEILQSSTFFL 251

  Fly   241 INQHVSLSFPRPHSPNMIEVGGMHIDG-KWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPS 304
            .|.:..|||..|....:|::||..|:. |...|.|:..:.:: ..:..|..|.|:.:::.|:|..
Worm   252 TNSNPYLSFSTPTISKVIQIGGFTIESFKTTTLDEEFNKILS-LRNNTILVSFGTVIQSSDMPDD 315

  Fly   305 KVQEILKALGGLKQRV-LWKFELDN--LPNK-PENVYISDWFPQTDILAHPKIMAFVTHGGMLST 365
            ....:::|...:.... :||:|.|:  |.|| .|||.:|.|.||..:||..::..||||||:.||
Worm   316 FKTGLIEAFRRMPDATFIWKYEEDDKTLKNKLSENVVLSKWIPQPALLADSRLDLFVTHGGLGST 380

  Fly   366 TESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLD-FKTLNAVEFRKAIERITSEPSYTKVVQG 429
            .|..|.....|.:|:||||..|.....::|..|:.| |..:::.:..:.|:.|.:...|.|..:.
Worm   381 MEVGYAGVSSIMVPVFSDQGVNAEMLARHGGAIVYDKFDLVDSKKLMETIQMILNNSDYRKNSKR 445

  Fly   430 ISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVL-LIIFVVMVLLLI-- 491
            :|....:|...|.:..:...|...|......|:..|.:.|:.:::.:|.| |::..:.|:.|:
Worm   446 LSDILHNQPMDPKQVLLNHCEFAARFAQVDNLEPYANKYNFIEFYCLDSLALVVCTISVVALVMF 510

  Fly   492 -VLPITIYKLLKKLLLKGE 509
             :|...:..:::||.||.|
Worm   511 KILSFVVNSVIEKLKLKKE 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	130/505 (26%)
ugt-3	NP_506203.2	egt	1..457	CDD:223071	122/465 (26%)
ugt-3	NP_506203.2	UDPGT	27..525	CDD:278624	128/512 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810