DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and ugt-41

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_504818.2	Gene:	ugt-41 / 184295	WormBaseID:	WBGene00017336	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	550	Identity:	142/550 - (25%)
Similarity:	240/550 - (43%)	Gaps:	73/550 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTDVS 70
            :||.|:.|:..:||:|||:|..:.|.||......||..|.:|||.:||:|:....|    :.::|
Worm     5 IILLLVLSISNTSGFNYLVVSPAFGHSHSTFMGKLADSLTEAGHNVTVLSIIISSK----FRNIS 65

  Fly    71 VPN------VIE-----------VMGGDIGALWASIQKTYTQNLIDHYQMGFRITRG---LFEDS 115
            ...      |:|           :...|....|.  |:......|..|.|..::...   .|.|.
Worm    66 YTKSTKDIVVVETTTEQDQLTENMENDDFARYWT--QEGTMLETIPSYLMFLKMAEDGYKTFRDH 128

  Fly   116 NF--QDFLKSNQ-SFDAIICETFYNDAHYGLA--EHFNAPLIGLATGGGLTF---ITDMVGSPAP 172
            ..  .|:||:|: .:||:..|:|:   ..|.|  |:...|:....|  .:|.   ..:::|.|..
Worm   129 ALPQMDYLKNNRPQYDAVFFESFF---FMGKAIQEYLEIPVFLPVT--SITHDYRFAELIGEPVS 188

  Fly   173 ASFVPHIMLPFNDHMSLYERLLN----------VAFLGYERVLLDYYFLPTQEKLYKEFFPGNKR 227
            .|::......|.:.|:..|||.|          :||..: :.|.|    |:::.|.:..:
Worm   189 PSYLSGYFTNFGNIMNFQERLTNTISYYLGQILIAFPNW-KTLQD----PSKDLLVESEY----- 243

  Fly   228 CFYKMRRNASLVLINQHVSLSFPRPHSPNMIEVGGMHIDG---KWNPLPEKIERFINESEHGAIY 289
                  ..|..|.||.:..:.||||.....||:||:.:|.   |...:.||.:..:.:..|. :.
Worm   244 ------HRAPYVFINSNPYIDFPRPLLSKTIEIGGITVDVKKLKSEKVDEKWDNILKKRPHN-VL 301

  Fly   290 FSMGSNLKTKDLPPSKVQEILKALGGLKQ-RVLWKFELD--NLPNKPENVYISDWFPQTDILAHP 351
            .|.||..|:..:|....:.::|.:...|. ..:||:|.:  :..|..||:..|.|.|||.:||..
Worm   302 ISFGSMFKSIYMPDFYKENMVKVMKSFKNVSFIWKYESEETSFANGAENIIFSKWVPQTALLADS 366

  Fly   352 KIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAH-AEQNGYGIMLDFKTLNAVEFRKAIE 415
            ::.||.||||:.|..|..|..||.:..|:|:||..|... ...||...:..|...|....|.|:.
Worm   367 RLSAFFTHGGLGSVNELSYLGKPALLCPLFADQIRNSKMLTRHNGSIEISKFNLENYNTLRSALH 431

  Fly   416 RITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLL 480
            .|....||::..:.::.:...|...|.|..:...|...|........|..:.:.:..|:.:||:.
Worm   432 SILFAESYSENAEKLAKKLEYQPTKPKELFVRHAEFAARFGEQPAQDSNLRTMGFAAYYLLDVIA 496

  Fly   481 IIFVVMVLLLIVLPITIYKLLKKLLLKGER 510
            .:...::|::.|:.|.|.:::|.|.:|.:|
Worm   497 FLTSFVLLVIFVVFIMIRQIVKLLTIKSKR 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	134/518 (26%)
ugt-41	NP_504818.2	UDPGT	22..510	CDD:278624	128/515 (25%)
ugt-41	NP_504818.2	Glycosyltransferase_GTB_type	26..512	CDD:299143	126/513 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810