DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302K1 and ugt-38

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_504812.1	Gene:	ugt-38 / 184294	WormBaseID:	WBGene00017333	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	560	Identity:	136/560 - (24%)
Similarity:	219/560 - (39%)	Gaps:	100/560 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LILGLLCSLGYS--SGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVS-VFPQKKPIPGYT 67
            |:|.||.:| |:  |.:|:|:.......||......:|..|..|||.:...: :..:|.....||
Worm     2 LLLALLFTL-YANVSSFNFLVFCPLFAHSHSKFFATIADSLTDAGHNVAFFTPIIVEKYRNFNYT 65

  Fly    68 DVSVPNVI-------------EVMGGDIGALWAS-------------IQKTYTQNLIDHYQMGFR 106
            . |..:|:             ::..||....|..             .||.|.:
Worm    66 K-STKDVVYMEPSKKLKEYGRQMSTGDFVRYWTEDSTATEIITVVRIFQKMYNE----------- 118

  Fly   107 ITRGLFEDSNFQ---DFLKSNQSFDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDM-- 166
              :|.....|.:   |..|  :.||.||.|.|...| |.|.::...|          |||..:
Worm   119 --QGTVMKDNIEILNDLKK--RKFDVIIFEAFIFSA-YPLMDYLEIP----------TFIPSLSV 168

  Fly   167 ---------VGSPAPASFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFF 222
                     :|.|...|.|...:.||.|.:|:.||..|...:.|...::.|   ||.......:.
Worm   169 AHDTALAVEIGEPVMPSVVSDCLSPFGDKLSITERAFNAFMVPYFDFMIGY---PTHRSFKPPYN 230

  Fly   223 PGNKRCFYKMRRNASLVLINQHVSLSFPRPHSPNMIEVGGMHIDGK----------WNPLPEKIE 277
            |.:.|....   .||.|.:|.:..:.||||.....|::||:.:|..          |:.:.:..|
Worm   231 PIDIRSIVP---EASFVFLNSNPFVDFPRPTLTKTIQIGGISVDSNELRSQKLDETWSEILKLRE 292

  Fly   278 RFINESEHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQ-RVLWKFE---LDNLPNKPENVYI 338
            :        .:..|.||.|.:||:|......:..|:...|. ..:||:|   .|......||::.
Worm   293 K--------TMLVSFGSMLYSKDMPFKNKIALKNAMEKFKNVTFIWKYEDDSSDEFAKGIENIHF 349

  Fly   339 SDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFK 403
            :.|.|||.:||..::.||:||.|:.|.||..|..||.|..|...||..|.....::...|.|...
Worm   350 AKWVPQTALLADSRLSAFLTHAGLGSITELSYLGKPAILCPQLFDQMRNTKMLVRHNGSIELSKY 414

  Fly   404 TLNAVE-FRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQR 467
            .|...| ..:|.:.|..:.||.|..|.::.:..:|...|.|..:...|:..|......|...:::
Worm   415 DLGKSEKIIEAFQAILFDSSYAKNAQKLAEQLENQPIKPKEMMVKHAEYAARFGRLPSLDPYSRK 479

  Fly   468 LNWWQYHNVDVLLIIFVVMVLLLIVLPITIYKLLKKLLLK 507
            :::.:|..:||..|...::..::.|:...:..|....|:|
Worm   480 MSFVEYFLLDVAAICVFILTFVVFVVTKLVQSLFDIFLIK 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	131/531 (25%)
ugt-38	NP_504812.1	Glycosyltransferase_GTB_type	12..512	CDD:299143	127/540 (24%)
ugt-38	NP_504812.1	UDPGT	29..521	CDD:278624	127/532 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810