DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and ugt-7

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_504343.2	Gene:	ugt-7 / 182577	WormBaseID:	WBGene00015739	Length:	530	Species:	Caenorhabditis elegans

Alignment Length:	535	Identity:	124/535 - (23%)
Similarity:	223/535 - (41%)	Gaps:	63/535 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITV-----VSVFPQKKPIPGYTDVSVPN 73
            |.||..:.||::......||......:|..|...||.:.|     |.....||.|.. .|:.:.|
Worm    10 LQYSYAFKYLIISPIYSYSHVKFMSNIADTLADHGHEVVVFQQQIVEALRDKKVIKN-PDIKIIN 73

  Fly    74 V-IEVMGGDI--GALWASIQKTYTQNLIDHYQMGFRITRGL-----------FEDSNFQDFLKSN 124
            . ....|.:.  ....:|:.|.:|.|...:.....:....:           |||.:....|||
Worm    74 YEANTAGKEFYRNRPKSSVTKYWTTNQAANPSAADQFAEAMSKDLEHMCLQVFEDKSLHTMLKS- 137

  Fly   125 QSFDAIICETFYNDAHYGLAEHFNAP--LIGLATGGGLTFITDMVGSPAPASFVPHIMLPFNDHM 187
            :.||.::.|.|.....| |.::...|  ::.:|: ..:..:...:|.|:..:|:|.....:.:..
Worm   138 EHFDVLLAEPFDPCGLY-LGDYLKIPSTIVAMAS-SRIDPVQWALGQPSGLNFIPGPDSKYGEES 200

  Fly   188 SLYERLLNV-AFLGYERVLLDYYFLPTQEKLYK---------EFFPGNKRCFYKMRRNASLVLIN 242
            .:::|:.|| .|....|:....|:....:..:|         |....:...||           |
Worm   201 GVWDRINNVWMFFMRTRMFRAVYWNLLDKLRFKTGLEIRNIDEIVAESAYLFY-----------N 254

  Fly   243 QHVSLSFPRPHSPNMIEVGGMHID-GKWNP--LPEKIERFINESEHGAIYFSMGSNLKTKDLP-- 302
            .:..|.||.|.....:.:||..:: ..|..  |||.::..: :.....::.|.||.:::.|:|
Worm   255 SNPYLDFPFPSLTKCVPIGGFSMNTTNWKSENLPENLKNIL-QKRPNTVFISFGSVIRSADMPQE 318

  Fly   303 -PSKVQEILKALGGLKQRVLWKFELDN----LPNKPENVYISDWFPQTDILAHPKIMAFVTHGGM 362
             .:.:.|:.|.:..:  ..:||:|.:.    ..|.||||::..|.||..:||..::..|:||||:
Worm   319 YKNAIIEVTKLMSDV--TFIWKYEDEKDEEMRGNIPENVHLMKWLPQPALLADSRVSLFITHGGL 381

  Fly   363 LSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYG-IMLDFKTLNAVEFRKAIERITSEPSYTKV 426
            .|..|..|..||.|.:|:|.||..|.....::|.. :...|:..||.:.:|.|:.:...|.|...
Worm   382 GSIMEVAYSGKPAIVIPLFFDQPMNGEMLRRHGGAEVYSKFELSNAKKLKKVIQNMIQNPKYLAN 446

  Fly   427 VQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDV---LLIIFVVMVL 488
            .:.:|...:.|...|||..:...|.....:....|...::.||::|:..:|:   |||:|::..|
Worm   447 AKKLSNLLQKQPINPIERLVKHAEFAAEFKKLPELDPYSRHLNFFQFFFLDIVATLLILFMLSAL 511

  Fly   489 LLIVLPITIYKLLKK 503
            .:..:...|..:..|
Worm   512 FVYWITYVICSVRSK 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	117/510 (23%)
ugt-7	NP_504343.2	egt	1..477	CDD:223071	112/484 (23%)
ugt-7	NP_504343.2	UDPGT	27..521	CDD:278624	117/511 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810