DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and ugt-17

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001122841.1	Gene:	ugt-17 / 179406	WormBaseID:	WBGene00007422	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	539	Identity:	131/539 - (24%)
Similarity:	250/539 - (46%)	Gaps:	56/539 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FTLILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTIT-VVSVFPQ-KKPIPGY 66
            :.:|..|...:.||:.|..|:...:.|.||.|....::..|:.|||.:| ::.:..| ||.:.|
Worm     5 YYIIFILFSIIDYSNSYKVLVFNPAFGASHSNFLGKISDILIDAGHDVTMLIPIAMQGKKHLVG- 68

  Fly    67 TDVSVPNVIEV-----------MGGDIGALWASIQKTYTQNLIDHYQMG-FRITRG-----LFED 114
             ...|.|:|.:           ..|....|...|.|..:...:.....| |..|.|     :|:.
Worm    69 -SKKVKNIIRIDQDPRSIELYKQTGAEDVLRKKIWKVESDIALFFKMAGNFSKTCGYQCQHVFQQ 132

  Fly   115 SNFQDFLKSNQSFDAIICETFYNDAHYGLAEHFNAPLIGLAT--GGGLTFITDMV----GSPAPA 173
            :...:.|| |:.|:..|.|:.: ...|.|.:|     :|:.|  ........|:|    |.|:.:
Worm   133 TEILEKLK-NEHFELGITESLF-ICGYPLFDH-----LGVKTIINADSVLFMDIVKCTLGEPSSS 190

  Fly   174 SFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDYYF--LPTQEKL--YKEFFPGNKRCFYKMRR 234
            :|.|.::.|..|.|:|.||:.|..     ::|:..||  :..:|:|  .:.::.|:| .:.::..
Worm   191 TFYPALISPMTDKMTLVERIKNAI-----QMLIPVYFSKMRFEEELSMIEPYYNGSK-TWEELLE 249

  Fly   235 NASLVLINQHVSLSFPRPHSPNMIEVGGMHIDGKWNPLP---EKIERFINESEHGAIYFSMGSNL 296
            |.:..::|.:..|.:..|..|..:.:|||.:..|....|   ::.:..:|..:.. :..|.|||.
Worm   250 NVAFNMVNSNRYLDYASPTLPKTVFIGGMQVKTKKQGTPKLNKEWDDLLNIRKEN-VLVSFGSNA 313

  Fly   297 KTKDLPPSKVQEILKALGGLKQ-RVLWKFELDN--LPNKPENVYISDWFPQTDILAHPKIMAFVT 358
            .:.::|....:..|.....:.: ..:||:|.:|  :.....||.::.|.||:|:||..::..|||
Worm   314 FSSEMPDEFKKSFLDVFASMPEITFIWKYEQENSTIAMHLSNVKMTTWMPQSDLLADNRLSLFVT 378

  Fly   359 HGGMLSTTESIYHAKP----VIGLPIFSDQFFNMAHAEQNGYGIMLDFKTL-NAVEFRKAIERIT 418
            |||:.|:.|..|...|    :..:|:.:||..|.....::|..|.||...| |....|.||:.|.
Worm   379 HGGLGSSIELAYQGTPAVVNIFKIPLMADQPRNAHMLTRHGGAIQLDKTNLDNPQMIRDAIKTIL 443

  Fly   419 SEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIF 483
            ...|||:..:.::....||..||.|..:...:...:......|:|..::||.:|:::.|:|:::.
Worm   444 DNDSYTENARKLAQILEDQPYTPAEVVLKHCDFAVKFGVLDTLQSEGRKLNVFQFYSYDILVVVC 508

  Fly   484 VVMVLLLIVLPITIYKLLK 502
            .:::.:::.:.:.:::.:|
Worm   509 FLIITVVVFIVLYVFQCIK 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	129/515 (25%)
ugt-17	NP_001122841.1	egt	1..513	CDD:223071	130/523 (25%)
ugt-17	NP_001122841.1	UDPGT	22..538	CDD:278624	126/522 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860