DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and ugt-51

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_504388.2	Gene:	ugt-51 / 178905	WormBaseID:	WBGene00015369	Length:	524	Species:	Caenorhabditis elegans

Alignment Length:	522	Identity:	117/522 - (22%)
Similarity:	227/522 - (43%)	Gaps:	63/522 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 NYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTDVSVPNV------IEVMG 79
            |.:..:|:.|:||.:.|.:|...|.:.|||:.:|        |....|::..|.      ...:|
Worm    23 NIVFFINAIGKSHLDFGDSLIDSLKEKGHTVDLV--------IARINDLAKGNENSKADRFYTLG 79

  Fly    80 GDIGALWASIQ---KTYTQN--LIDHYQ----MGFRITRGLFEDSNFQDFLKSNQSFDAIICETF 135
            ...|:.|..:.   ..:..|  .||.::    :|.::......|.....|| |.:|:|..:...|
Worm    80 FKNGSSWHKLNHLTSPFENNPFPIDGFRQYTLIGNQLCEIALHDEKLHQFL-SEKSYDVGVVSVF 143

  Fly   136 -------YNDAHYGLAEHFNA-PLIGLATGGGLTFITDMVGSPAPASFVPHIMLPFNDHMSLYER 192
                   .|.|.......||| ||:.:.|      :|  :|.|..||.|..:...| |..:|..:
Worm   144 DYCGIGILNKAGVSSITTFNAVPLMSIQT------VT--IGLPNIASQVVPLFYTF-DLATLSGK 199

  Fly   193 LLNVAFLGYERVLLDYYFLPT----QEKLYKEFFPGNKRCFYKMRRNASLVLINQHVSLSFPRPH 253
            |.|:....:    ::::.:||    ||.|:::.: |......::.....|..:|.:..:..|...
Worm   200 LWNLITWAH----INFHQIPTLRKEQELLFQKVY-GPSFSINEVIDKVDLSFVNSNEIMETPMLI 259

  Fly   254 SPNMIEVGGMHIDGKWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQ 318
            :..:..:||:::... .|:...::..:::|.:|.|.||.|:.:.....|...|:..:|......:
Worm   260 NHRIQYIGGINLKTP-KPVDHHLDNLLSKSSNGTIIFSFGTQIPGAVYPRYAVRNFVKVFKKYPE 323

  Fly   319 -RVLWKFEL----DNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGL 378
             ..|||:.:    :.|....|||.:.||.||||:|..|:::.|::|.|:.|..|:.|..||:|.:
Worm   324 YTFLWKYNVQPGEEKLFEDAENVILLDWLPQTDLLYDPRVIGFISHVGLNSFNEASYAGKPIIAI 388

  Fly   379 PIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIE 443
            |:|:||..|..:....|...:|:...|:.......:..|..:.|||:..:.:.....::...|.:
Worm   389 PLFADQPHNARNGVARGTTYLLNKSKLSEESIENGLRAILFDKSYTESARKLQKMLVEKPTKPKD 453

  Fly   444 NAIYWVEHVTRHQGAAYLKS-AAQRLNWWQYHNVDVLLII------FVVMVLLLIVLPITIYKLL 501
            ..:.|:|:...:.|...:.: ...::...:|:.||.::.|      |..:...:....::..:|:
Worm   454 RFVEWMEYAAVNPGLHKIFALPGAKMGNIEYYCVDTIVFIAFSCVTFTYIFFKMAKFSLSFIRLV 518

  Fly   502 KK 503
            ||
Worm   519 KK 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	112/491 (23%)
ugt-51	NP_504388.2	UDPGT	43..505	CDD:278624	107/485 (22%)
ugt-51	NP_504388.2	egt	<217..496	CDD:223071	63/280 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810