DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and Ugt2b38

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_598655.1	Gene:	Ugt2b38 / 100559	MGIID:	2140794	Length:	530	Species:	Mus musculus

Alignment Length:	524	Identity:	157/524 - (29%)
Similarity:	235/524 - (44%)	Gaps:	97/524 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LVKAGHTITVV--SVF----PQKKP------IPGYTDVSVPNV-------IEVMGGDIGALWASI 89
            ||:.||.:||:  |.:    |:|.|      .|  |.||..|:       ::|        |
Mouse    46 LVQRGHEVTVLRPSAYYVLDPKKSPGLKFETFP--TSVSKDNLENFFIKFVDV--------W--- 97

  Fly    90 QKTY-------------TQNLIDHYQMGFRITRGLFED--SNFQDFLKSNQS-FDAIICETFYND 138
              ||             .||:||.:...|   ..|.:|  ||.:...|..:| ||.::.:..
Mouse    98 --TYEMPRDTCLSYSPLLQNMIDEFSDYF---LSLCKDVVSNKELMTKLQESKFDVLLSDPV--- 154

  Fly   139 AHYG--LAEHFNAPLIGLATGGGLTFITDMVGSPA------------PASFVPHIMLPFNDHMSL 189
            |..|  :||....|           |:..:..||.            |.|:||.|:......|:.
Mouse   155 ASCGELIAELLQIP-----------FLYSIRFSPGYQIEKSSGRFLLPPSYVPVILSGLGGQMTF 208

  Fly   190 YERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFP---GNKRCFYKMRRNASLVLINQHVSLSFPR 251
            .||:.|:..    |:..|::|....:|.:..|:.   |......:....|.:.||..:..|.||.
Mouse   209 IERVKNMIC----RLYFDFWFQMFNDKKWDSFYSEYLGRPTTLAETMGKAEMWLIRSNWDLEFPH 269

  Fly   252 PHSPNMIEVGGMHIDGKWNPLPEKIERFINES-EHGAIYFSMGSNLKTKDLPPSKVQEILKALGG 315
            |..||:..|||:|.... .|||:.:|.|:..| :||.:.||:||  ...::...|...|..||..
Mouse   270 PTLPNVDYVGGLHCKPA-KPLPKDMEEFVQSSGDHGVVVFSLGS--MVSNMTEEKANTIAWALAQ 331

  Fly   316 LKQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPI 380
            :.|:|||||:.........|..:..|.||.|:|.|||..|||||||.....|.|||..|:||:|:
Mouse   332 IPQKVLWKFDGKTPATLGHNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEVIYHGIPMIGIPL 396

  Fly   381 FSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENA 445
            |.:|..|:||....|..:.|:.:|::..:...|:|.:...|.|.|....:|..:.||...|::.|
Mouse   397 FGEQHDNIAHMVAKGAAVTLNIRTMSRSDVLNALEEVIDNPFYKKNAIWLSTIHHDQPTKPLDRA 461

  Fly   446 IYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDV---LLIIFVVMVLLLIVLPITIYKLL--KKLL 505
            ::|||.|.||:.|.:|:|....|.|.|||.:||   ||....|.::|.:...:.||:..  |:..
Mouse   462 VFWVEFVMRHKRAKHLRSLGHNLTWHQYHFLDVIGFLLSCVAVTIVLTVKCLLFIYRFFVKKEKK 526

  Fly   506 LKGE 509
            :|.|
Mouse   527 IKNE 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	148/491 (30%)
Ugt2b38	NP_598655.1	egt	8..506	CDD:223071	151/498 (30%)
Ugt2b38	NP_598655.1	UDPGT	24..526	CDD:278624	155/518 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840488
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.690