Protein Alignment Ugt304A1 and Ugt2b35

DIOPT Version :10

• Sequence 1: NP_652619.1
• Gene: Ugt304A1 / 53501
• FlyBaseID: FBgn0040250
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001004271.1
• Gene: Ugt2b35 / 83808
• RGDID: 620895
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 556
• Identity: 137/556 - (24%)
• Similarity: 250/556 - (44%)
• Gaps: 103/556 - (18%)

  Fly     4 PGRWLLPMFWLISNSICWIRSSRI--LVIAPFESHSQCMLVTPYIQALKDRGHQLTVIH------ 60
            ||:|:..:. |:..|.|: :|...  :::.|.| :|..|.:...::.|..:||::||:.
  Rat     2 PGKWISALL-LLQISFCF-KSGNCGKVLVWPME-YSHWMNIKIILEELVQKGHEVTVLRPSASVF 63

  Fly    61 --------------AYKHCMHKIED--VTFIRIWYNN-------NVFLEFEESVGIASANNKWEE 102
                          ......|.:|:  ..|:.:|...       :.||..::::         :|
  Rat    64 LDPKETSDLKFVTFPTSFSSHDLENFFTRFVNVWTYELPRDTCLSYFLYLQDTI---------DE 119

  Fly   103 ISSMSSLMANATLNVLNNVEVRALMKSRITFDAVVLEAGYSDVLYGMAAHFSAQLIGICTCVADW 167
            .|.....:....  |.|...:..|.:|:  ||.|     :||.: |......|:|:.|...   :
  Rat   120 YSDYCLTVCKEA--VSNKQFMTKLQESK--FDVV-----FSDAI-GPCGELIAELLQIPFL---Y 171

  Fly   168 NINNLVGFSTSTLTEPIMPFRAKYVKNVW----------DRIYN---------WLYTTEE--WLL 211
            ::....|::.......:: |...||..::          :|::|         |..|..|  |
  Rat   172 SLRFSPGYTIEKYIGGVL-FPPSYVPMIFSGLAGQMTFIERVHNMICMLYFDFWFQTFREKKW-- 233

  Fly   212 INLVFLPKQRLIHDHFFGHL---EKSFHEIRQDFALMLLNQHFSLFRARPNVPGMVEVAGLHIPK 273
                         |.|:...   ..:..||.....:.|:..::.|....|..|.:..:.|||...
  Rat   234 -------------DPFYSKTLGRPTTLAEIMGKAEMWLIRSYWDLEFPHPISPNVDYIGGLHCKP 285

  Fly   274 EDPQLPSDLQVFIDEA-EHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQRVIWKFDGESTMS 337
            ..| ||.|::.|:..: ||||::||||  ...:::..:...|:......:||:|:|:|||:...:
  Rat   286 AKP-LPKDIEDFVQSSGEHGVVVFSLG--SMVRNMTEEKANIIAWALAQIPQKVLWRFDGKKPPT 347

  Fly   338 LGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGV 402
            ||.:....|.|||..:|.||..|.|::|.|...:.||.::..|::|:|.|.:|..|:..|..:|.
  Rat   348 LGPNTRLYKWLPQNDLLGHPKTKAFVTHGGANGIYEAIHHGIPMIGIPLFGEQHDNIAHMVAKGA 412

  Fly   403 ALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHM 467
            |:|:|..:::..::.:|:..:||.|.|:::|:.:|....|||..|||.|::|.|:::|:|||.|:
  Rat   413 AVEVNFRTMSKSDMLNALEEVINNPFYKKNAMWLSTIHHDQPTKPLDRAVFWIEFVMRHKGAKHL 477

  Fly   468 KISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLVL 503
            :.....|..:.|:|||   ::|..|:.|...|.|.|
  Rat   478 RSLGHNLPWYQYHSLD---VIGFLLTCVAVTVVLAL 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	GT1_Gtf-like	26..454	CDD:340817	112/483 (23%)
Ugt2b35	NP_001004271.1	UDPGT	24..527	CDD:278624	130/532 (24%)