DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt304A1 and UGT76E1

DIOPT Version :9

Sequence 1:	NP_652619.1	Gene:	Ugt304A1 / 53501	FlyBaseID:	FBgn0040250	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_200766.2	Gene:	UGT76E1 / 836077	AraportID:	AT5G59580	Length:	453	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	116/521 - (22%)
Similarity:	196/521 - (37%)	Gaps:	148/521 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 ILVIAPFESHSQCMLVTPYIQ---ALKDRGHQLTVIHAYKHCMHKIEDVTFIRIWYNNNVFLEFE 88
            :||..|.:.|     |||.:|   ||..:|..:||:....:.:...:|       :::..||...
plant    11 VLVPVPAQGH-----VTPIMQLGKALYSKGFSITVVLTQYNRVSSSKD-------FSDFHFLTIP 63

  Fly    89 ESVGIASANNKWEEISSMSSLMANATLNVLNNVEVRALMKSRITFDAVVLEAG--YSDVLYGMAA 151
            .|:          ..|.:.:|.....|..||.: ..|..|..|  ..::.|.|  .:.|:|....
plant    64 GSL----------TESDLKNLGPFKFLFKLNQI-CEASFKQCI--GQLLQEQGNDIACVVYDEYM 115

  Fly   152 HFSAQLIGICTCVADWNINNLVGFSTSTLTEPIMPFRAKYVKNVWDRIYNWLYTTEEWLL----- 211
            :||.      ..|.::.:.::: |||::.|       |...::|..|:     ..|.:||
plant   116 YFSQ------AAVKEFQLPSVL-FSTTSAT-------AFVCRSVLSRV-----NAESFLLDMKDP 161

  Fly   212 ------------INLVFLPKQRLIHDHFFGHLE---KSFHE---IRQDFALM------LLNQHFS 252
                        :....||...      ||.||   |.:.|   ||...|::      |.:...:
plant   162 KVSDKEFPGLHPLRYKDLPTSA------FGPLESILKVYSETVNIRTASAVIINSTSCLESSSLA 220

  Fly   253 LFRARPNVPGMVEVAGLHIPKEDPQ--LPSDLQV--FIDEAEHG-VILFSLG--LEQDSKDLPRK 310
            ..:.:..|| :..:..|||....|.  |..|...  ::::.:.| ||..|||  ...::||:..
plant   221 WLQKQLQVP-VYPIGPLHIAASAPSSLLEEDRSCLEWLNKQKIGSVIYISLGSLALMETKDMLE- 283

  Fly   311 TQEILVETFKSVPQRVIWKF------DGESTMSLGTDI--------YHSKLLPQQAILAHPNVKL 361
                :....::..|..:|..      ..|.|.||..:.        |..|..||..:|.||.|..
plant   284 ----MAWGLRNSNQPFLWVIRPGSIPGSEWTESLPEEFSRLVSERGYIVKWAPQIEVLRHPAVGG 344

  Fly   362 FISHCGMMSVIEAAYYAKPVLGLPSFFDQ---FRNLEIMKEEGVALELNINSLTVKELKDAIHSM 423
            |.||||..|.:|:.....|::..|...||   .|.||.:...||.||..::..||:.   |:..:
plant   345 FWSHCGWNSTLESIGEGVPMICRPFTGDQKVNARYLERVWRIGVQLEGELDKGTVER---AVERL 406

  Fly   424 INE---PEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNF 485
            |.:   .|.|:..:.:.::        |.|:       ::.:|:             .:.|||||
plant   407 IMDEEGAEMRKRVINLKEK--------LQAS-------VKSRGS-------------SFSSLDNF 443

  Fly   486 I 486
            :
plant   444 V 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	111/513 (22%)
Ugt304A1	NP_652619.1	YjiC	42..445	CDD:224732	104/463 (22%)
UGT76E1	NP_200766.2	Glycosyltransferase_GTB_type	1..450	CDD:299143	116/521 (22%)
UGT76E1	NP_200766.2	YjiC	7..429	CDD:224732	109/484 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050