Protein Alignment Ugt304A1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_652619.1
• Gene: Ugt304A1 / 53501
• FlyBaseID: FBgn0040250
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001034638.1
• Gene: Ugt1a5 / 574523
• RGDID: 1583689
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 530
• Identity: 138/530 - (26%)
• Similarity: 253/530 - (47%)
• Gaps: 81/530 - (15%)

  Fly    14 LISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIHAYKHCMH-KIED------ 71
            |:..::.|....::||. |.|. |..:.:...::.|..||||..|: |.:..:| |.||
  Rat    15 LLLYALPWAEGGKVLVF-PMEG-SHWLSMRDVVRELHARGHQAVVL-APEVTVHIKEEDFFTLQT 76

  Fly    72 --VTFIRIWYN----NNVFLEFEESVGIASANNKWEEISSMSSLMANATLNVLNNVEVRALMKSR 130
              |.:.|..:.    .|:.:.||....:.:.....|.:.::|:::..:.:|:|:|..:...:.|.
  Rat    77 YPVPYTRQGFRQQMMRNIKVVFETGNYVKTFLETSEILKNISTVLLRSCMNLLHNGSLLQHLNSS 141

  Fly   131 ITFDAVVLEAGYSDVLYGMAAHFSAQLIGICT--------CVADWNINNLVGFSTSTLTEPIMPF 187
             :||.|:     :|.:....| ..|:.:||.|        |..|           |..|:  .|.
  Rat   142 -SFDMVL-----TDPVIPCGA-VLAKYLGIPTVFFLRYIPCGID-----------SEATQ--CPK 186

  Fly   188 RAKYVKNV----------WDRIYNWLYTTEEWLLINLVFLPKQRLIHDHFFGHLEKSFHEIRQDF 242
            .:.|:.|:          ..|:.|.||.           |..:.:.|..|..:...:...::::.
  Rat   187 PSSYIPNLLTMLSDHMTFLQRVKNMLYP-----------LALKYICHFSFTRYESLASELLQREV 240

  Fly   243 ALMLLNQHFS--LFRA-------RPNVPGMVEVAGLHIPKEDPQLPSDLQVFID-EAEHGVILFS 297
            :|:.:..|.|  |||.       ||.:|.||.:.|::...:.| |..:.:.::: ..|||:::||
  Rat   241 SLVEVLSHASVWLFRGDFVFDYPRPVMPNMVFIGGINCVIKKP-LSQEFEAYVNASGEHGIVVFS 304

  Fly   298 LGLEQDSKDLPRKTQEILVETFKSVPQRVIWKFDGESTMSLGTDIYHSKLLPQQAILAHPNVKLF 362
            ||  ....::|.|....:.|....:||.|:|::.|....:|..:....|.|||..:|.||..:.|
  Rat   305 LG--SMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAF 367

  Fly   363 ISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEP 427
            |:|.|...:.|......|::.:|.|.||..|.:.|:..|..:.||:..:|..:|::|:.::||..
  Rat   368 ITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNK 432

  Fly   428 EYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRL 492
            .|:|:.:.:|...:|:||.|||.|::|.||::|:|||.|::.:...|..:.|:|||   ::|..|
  Rat   433 SYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLD---VIGFLL 494

  Fly   493 SLVVALVFLV 502
            ::|:.:||:|
  Rat   495 AIVLTVVFIV 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	GT1_Gtf-like	26..454	CDD:340817	117/468 (25%)
Ugt1a5	NP_001034638.1	UDPGT	26..522	CDD:278624	136/519 (26%)