DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt304A1 and ugt5g1

DIOPT Version :9

Sequence 1:	NP_652619.1	Gene:	Ugt304A1 / 53501	FlyBaseID:	FBgn0040250	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001107914.1	Gene:	ugt5g1 / 570913	ZFINID:	ZDB-GENE-080305-10	Length:	528	Species:	Danio rerio

Alignment Length:	557	Identity:	150/557 - (26%)
Similarity:	252/557 - (45%)	Gaps:	97/557 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RWLLPMFWLISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIHAYKH-CMH-- 67
            :||..:..|:| .:|......|||.....||...|.|  .::.|...||..||:.:.|. .:|
Zfish     6 KWLSALTCLLS-VVCCCHGGNILVFPEDGSHWVNMQV--ILRKLHTHGHSFTVVRSSKSWYIHEN 67

  Fly    68 ------------KIEDV--TFIRIWYNNNVFLE--------FEESVGIASANNKWEEISSMSSLM 110
                        :.|||  .:..:..:.::.|:        ||:.          ::|:::..:.
Zfish    68 SALYNTITVNPVETEDVGQDYFNMLLDRSLALQKMSPLVRFFEQQ----------KDITTVLKVF 122

  Fly   111 ANATLN----VLNNVE-VRALMKSRITFDAVVLEAGY-SDVLYGMAAHFSAQLIGICTCVADWNI 169
            .|..|.    :|::.| |::|.:::  ||.::.:..: :.||   .|:| .||..:      :|:
Zfish   123 HNGVLRMVSAMLDDAELVKSLREAK--FDLLLTDPAFPAGVL---VANF-LQLPMV------YNV 175

  Fly   170 NNLVGFSTSTLTEPIMPFRAKYVKNVWDRIYN--------WLYTTEEWLLINLVFLPKQRLIHDH 226
            ..|........|.|..|   .||.     :||        :|...|.:|......|.::.:|...
Zfish   176 RWLNAGDAHMQTAPSPP---SYVP-----MYNSLLHDQMSFLQRVENFLRYLCSLLQERYVIVPI 232

  Fly   227 FFGHLEKSFH------EIRQDFALMLLNQHFSLFRARPNVPGMVEVAGLHIPKEDPQLPSDLQVF 285
            :...||:.|.      .::|...:.|:...|.....||.:|.::.:.|... |....||.||:.|
Zfish   233 YRELLERHFPPGSDLLSMQQSADIWLMRMDFVFDFPRPTMPNIIYMGGFQC-KPAQALPVDLEEF 296

  Fly   286 IDEA-EHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQRVIWKFDGESTMSLGTDIYHSKLLP 349
            :..: ||||:..|||....:  |||...|.:...|..:||:|:|::.||...:||.:....:..|
Zfish   297 MQSSGEHGVVFMSLGAMVGA--LPRTITEAIASAFAKIPQKVMWRYHGERPSTLGNNTLLLEWFP 359

  Fly   350 QQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVK 414
            |..:|.||..:.|:||.|...:.||.|:..|||.||..||||.|:..::....|..|.:.:||.:
Zfish   360 QNDLLGHPKTRAFVSHGGTNGIYEAIYHGVPVLALPLLFDQFDNVMRLQVRNAARVLQVATLTSQ 424

  Fly   415 ELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDY 479
            |..:.:..::..|.||.|...:|:..|||||.|||:|.:|.||::|:|||.|::...:.|..:.|
Zfish   425 EFLEGLKDVLENPLYRSSIRKMSELHRDQPISPLDSATFWIEYVMRHKGAAHLRSEANNLAWYSY 489

  Fly   480 YSLDNFIMVGSRLSLVVALV----------FLVLSKS 506
            :|||..:.:     |.:|::          ||...||
Zfish   490 HSLDVLVFL-----LAIAVIAFWTSVYVCRFLCCRKS 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	139/517 (27%)
Ugt304A1	NP_652619.1	YjiC	42..445	CDD:224732	114/448 (25%)
ugt5g1	NP_001107914.1	UDPGT	24..526	CDD:278624	145/538 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584637
Domainoid	1	1.000	252	1.000	Domainoid score	I2043
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.790