Protein Alignment Ugt304A1 and Ugt2a2

DIOPT Version :9

• Sequence 1: NP_652619.1
• Gene: Ugt304A1 / 53501
• FlyBaseID: FBgn0040250
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 524
• Identity: 138/524 - (26%)
• Similarity: 241/524 - (45%)
• Gaps: 89/524 - (16%)

  Fly    28 LVIAPFESHSQCMLVTPYIQALKDRGHQLTVIHAYKHCMHKIEDVTFIRIWYNN--NVFLEFEES 90
            :|:.|.:. |..:.:...::.|..|.|.:||:..        .:..||    |:  :.|:.|||
Mouse    24 VVVWPTDG-SHWLNIKILLEELVQRNHSVTVLAP--------SETLFI----NSRLDAFINFEE- 74

  Fly    91 VGIASANNKWEEI----------------------SSMSSLMAN-ATLN------VLNNVEVRAL 126
            :.::...:|.:||                      ..:.:|:|. .|.|      ||||..|...
Mouse    75 IPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVLNNPTVMER 139

  Fly   127 MKSRITFDAVVLEAGYSDVLYG----MAAHFSAQLIGICTCVADWNINNLVGFSTSTLTE---PI 184
                       |:.|..|||..    |.....|..:||.....       :.||.:...|   ..
Mouse   140 -----------LQKGGFDVLLADPVTMCGELVALKLGIPFVYT-------LRFSPAFTVERHCGK 186

  Fly   185 MPFRAKYVKNVWDRIYNWLYTTEEWLLINLVFLPKQRLIHDHFFGHLEKSFH----------EIR 239
            :|....||......:.:.:...|.  :.|::....|..|...::|.....:.          |..
Mouse   187 IPAPISYVPAALSELTDQMSFGER--VKNIISYSLQDYIFKTYWGEWNSYYSKVLGRPTTLCETM 249

  Fly   240 QDFALMLLNQHFSLFRARPNVPGMVEVAGLHIPKEDPQLPSDLQVFID-EAEHGVILFSLGLEQD 303
            ....:.|:..::.....||.:|....|.|||.....| ||.:::.|:. ..|||:::||||  ..
Mouse   250 GKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKP-LPKEMEEFVQTSGEHGIVVFSLG--SM 311

  Fly   304 SKDLPRKTQEILVETFKSVPQRVIWKFDGESTMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGM 368
            .|:|..:...::......:||:|:|::.|:...:||::......:||..:|.||..:.||:|.|.
Mouse   312 VKNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGT 376

  Fly   369 MSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESA 433
            ..:.||.|:..|::|:|.|.||..|:..||.:|.|:|:|:|::|..:|.:|:.::||||.|:|:|
Mouse   377 NGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENA 441

  Fly   434 LAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVAL 498
            :.:|:...|||:.|||.|::|.|:::|:|||.|::::...|..|.|:|||   ::|..|:.|.:.
Mouse   442 MRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLD---VIGFLLACVASA 503

  Fly   499 VFLV 502
            :.||
Mouse   504 ILLV 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	129/500 (26%)
		YjiC	42..445	CDD:224732	112/451 (25%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	138/524 (26%)
		egt	<267..487	CDD:223071	80/222 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840205
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.790