DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt304A1 and RGD1559459

DIOPT Version :9

Sequence 1:	NP_652619.1	Gene:	Ugt304A1 / 53501	FlyBaseID:	FBgn0040250	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	XP_003751392.1	Gene:	RGD1559459 / 501907	RGDID:	1559459	Length:	530	Species:	Rattus norvegicus

Alignment Length:	503	Identity:	126/503 - (25%)
Similarity:	235/503 - (46%)	Gaps:	82/503 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 IQALKDRGHQLTVIHAYKHCMHKIEDVTFIRIWYNNNVFLEFEESVGIASANNKWEEISSMSSLM 110
            :..|..:||::.|:.......::::..:.|.       |..|..|..||..     |:..|..:
  Rat    43 LSELVKKGHEVVVLKPSVSFSYEVDKTSAIE-------FESFPSSYSIADV-----EVIFMDCV- 94

  Fly   111 ANATLNVLNNVEVRALMKSRITFDAVVLE------AGYSDVLYGMAAHFSAQLI------GICTC 163
                     |..:..|.|.......::|:      :.||:.|...|| |:.:|:      |....
  Rat    95 ---------NESIYELPKQSFWGYFLMLQKLFERTSDYSERLCRDAA-FNKELMTKLQNSGFDVI 149

  Fly   164 VAD------------------WNINNLVGFSTSTLTEPIMPFRAKYVKNVWDRIYNWLYTTEEWL 210
            :||                  :::....| ||.......:|....||......:.:.:...|.
  Rat   150 LADPFTPCGDLLAEILKIPLVYSLRFFPG-STYEKYSGGLPMPPSYVPIAMSELSDRMTFVER-- 211

  Fly   211 LINLVFLPKQRLIHDHFFGHL-EKSFHEIRQDFA--------------LMLLNQHFSLFRARPNV 260
            :.:::::    |..|.:|... ||.::|:..:..              :.|:..::.|....|.:
  Rat   212 VKHMIYV----LCFDFWFQVFDEKKWNELYTEVLGRPTTLSETMAKADIWLIRTYWDLEFPHPVL 272

  Fly   261 PGMVEVAGLHIPKEDPQLPSDLQVFIDEA-EHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQ 324
            |....|.|||.....| ||.:::.|:..: ||||::||||....|  |..:...::......:||
  Rat   273 PNFDFVGGLHCRPAKP-LPKEIEDFVQSSGEHGVVVFSLGSMVGS--LTEERANVIAAGLAQIPQ 334

  Fly   325 RVIWKFDGESTMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFD 389
            :|:|:|:|:...:||::....|.:||..:|.||..:.||:|.|...:.||.|:..||:|:|.|.|
  Rat   335 KVLWRFEGKKPETLGSNTRLYKWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPVVGIPLFGD 399

  Fly   390 QFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYW 454
            |..|:..:|.:|.|:.|:..:::..:|..|:.::.|:|.|:|:|:.:|:...|||:.|||.|::|
  Rat   400 QKDNIVHLKTKGAAVRLDFLTMSSTDLLTALRTVTNDPSYKENAMRLSRIHHDQPVKPLDRAVFW 464

  Fly   455 TEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLV 502
            .|:::|:|||.|::::...|....|:|||   ::|..|:.||.::|::
  Rat   465 IEFVMRHKGAKHLRVAGHDLSWVQYHSLD---VIGFLLACVVTVMFIL 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	117/479 (24%)
Ugt304A1	NP_652619.1	YjiC	42..445	CDD:224732	104/444 (23%)
RGD1559459	XP_003751392.1	UDPGT	24..527	CDD:278624	126/503 (25%)
RGD1559459	XP_003751392.1	egt	<270..508	CDD:223071	84/243 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344097
Domainoid	1	1.000	256	1.000	Domainoid score	I1959
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2882
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.690