Protein Alignment Ugt304A1 and Ugt1a1

DIOPT Version :9

• Sequence 1: NP_652619.1
• Gene: Ugt304A1 / 53501
• FlyBaseID: FBgn0040250
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_964007.2
• Gene: Ugt1a1 / 394436
• MGIID: 98898
• Length: 535
• Species: Mus musculus
• Alignment Length: 542
• Identity: 142/542 - (26%)
• Similarity: 253/542 - (46%)
• Gaps: 95/542 - (17%)

  Fly    19 ICWIRSSRILVIAPF---------ESHSQCMLVTP-----------YIQALKDRGHQLTV----- 58
            :||  |||:|::.|:         .||:..:||.|           .||.|:.:||::.|
Mouse     4 VCW--SSRLLLLLPYLLLCVFGPSASHAGRLLVFPMDGSHWLSMLGVIQQLQQKGHEVVVIAPEA 66

  Fly    59 -IHAYKHCMHKI---------EDVTFI-----RIWYNNNVFLEFEESVGIASANNKWEEISSMSS 108
             ||..:...:.:         |:||..     |..:|.:.||     :.:.....|.:..|||
Mouse    67 SIHIKEGSFYTLRKFPVPFQKENVTATLVELGRTAFNQDSFL-----LRVVKIYMKVKRDSSM-- 124

  Fly   109 LMANATLNVLNNVEVRALMKSRITFDAVVLEAGYSDVLYGMAAHFSAQLIGICTCVADWNINNLV 173
            |:|..: ::|:|.|..|.::.. .|||::.:.      :.......||.:.:.|.   :.:|.|.
Mouse   125 LLAGCS-HLLHNAEFMASLEES-HFDALLTDP------FLPCGSIVAQYLTVPTV---YFLNKLP 178

  Fly   174 GFSTSTLTEPIMPFRAKYV----------KNVWDRIYNWLYTTEEWLLINLVFLPKQRLIHDHFF 228
            ....|..|:  .|....||          .|...|:.|.|....|..:..:|:.|         :
Mouse   179 CSLDSEATQ--CPVPLSYVPKSLSFNSDRMNFLQRVKNVLLAVSENFMCRVVYSP---------Y 232

  Fly   229 GHL-------EKSFHEIRQDFALMLLNQHFSLFRARPNVPGMVEVAGLHIPKEDPQLPSDLQVFI 286
            |.|       |.:..::....::.|:...|.....||.:|.||.:.|::..::.| |..:.:.::
Mouse   233 GSLATEILQKEVTVQDLLSPASIWLMRSDFVKDYPRPIMPNMVFIGGINCLQKKP-LSQEFEAYV 296

  Fly   287 D-EAEHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQRVIWKFDGESTMSLGTDIYHSKLLPQ 350
            : ..|||:::||||  ....::|.|....:.|....:||.|:|::.|....:|..:....|.|||
Mouse   297 NASGEHGIVVFSLG--SMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQ 359

  Fly   351 QAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKE 415
            ..:|.||..:.||:|.|...:.|......|::.:|.|.||..|.:.|:..|..:.||:..:|..:
Mouse   360 NDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADD 424

  Fly   416 LKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYY 480
            |::|:.::||...|:|:.:.:|...:|:||.|||.|::|.||::|:|||.|::.:...|..:.|:
Mouse   425 LENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYH 489

  Fly   481 SLDNFIMVGSRLSLVVALVFLV 502
            |||   ::|..|::|:.:||:|
Mouse   490 SLD---VIGFLLAIVLTVVFIV 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	132/518 (25%)
		YjiC	42..445	CDD:224732	107/451 (24%)
Ugt1a1	NP_964007.2	egt	20..507	CDD:223071	133/521 (26%)
		UDPGT	30..526	CDD:278624	133/514 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840313
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.690