Protein Alignment Ugt304A1 and Ugt1a6b

DIOPT Version :10

• Sequence 1: NP_652619.1
• Gene: Ugt304A1 / 53501
• FlyBaseID: FBgn0040250
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_958812.3
• Gene: Ugt1a6b / 394435
• MGIID: 3580629
• Length: 531
• Species: Mus musculus
• Alignment Length: 553
• Identity: 135/553 - (24%)
• Similarity: 242/553 - (43%)
• Gaps: 108/553 - (19%)

  Fly     4 PGRWLLPMFWLISNSICW--IRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTV-------- 58
            |....||..:|.  .:.|  :...::||:....||  .:.:...::.|.:|||.:.|
Mouse     6 PAAQTLPAGFLF--LVLWASVLGDKLLVVPQDGSH--WLSMKEIVEHLSERGHDIVVLVPEVNLL 66

  Fly    59 IHAYKHCMHKIEDVTF--------------------------IRIWYNNNVFLEFEESVGIASAN 97
            :...|:...||..|.:                          :|.:.|:.:.||...|
Mouse    67 LGESKYYRRKIFSVPYSLEELQTRFRTFGRNQFVPGAPLMGPLREYRNSMLTLEMFFS------- 124

  Fly    98 NKWEEISSMSSLMANATLNVLNNVEVRAL-----------MKSRITFDAVVLEAGYSDVLYGMAA 151
                  :..|.|..:|||:.|...:..||           :...:...:|.|..|:...|..|..
Mouse   125 ------NCQSLLKDSATLSFLRENKFDALFTDPAMPCGVILAEYLNLPSVYLFRGFPCSLEHMLG 183

  Fly   152 HFSAQLIGICTCVADWNINNLVGFSTSTLTEPIMPFR-AKYVKNVWDR-IYNWLYTTEEWLLINL 214
            ...:.            ::.:..|.|........|.| |.::.|:.:. :|..||:..|.::.:|
Mouse   184 QSPSP------------VSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSKYEIIVTDL 236

  Fly   215 ----VFLPKQRLIHDHFFGHLEKSFHEIRQDFALMLLNQHFSLFRARPNVPGMVEVAGLHIPKED 275
                |.||               |.|:    .:|.||...|.....||.:|.|:.:.|::..|:.
Mouse   237 LKRDVSLP---------------SLHQ----NSLWLLRYDFVFEYPRPIMPNMIFIGGINCKKKG 282

  Fly   276 PQLPSDLQVFID-EAEHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQRVIWKFDGESTMSLG 339
             :|..:.:.::: ..|||:::||||  ....::|.|....:.|....:||.|:|::.|....:|.
Mouse   283 -KLTQEFEAYVNASGEHGIVVFSLG--SMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLA 344

  Fly   340 TDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVAL 404
            .:....|.|||..:|.||..:.||:|.|...:.|......|::.:|.|.||..|.:.|:..|..:
Mouse   345 KNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGV 409

  Fly   405 ELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMKI 469
            .||:..:|..:|::|:.::||...|:|:.:.:|...:|:||.|||.|::|.||::|:|||.|::.
Mouse   410 TLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRP 474

  Fly   470 SQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLV 502
            :...|..:.|:|||   ::|..|::|:.:||:|
Mouse   475 AAHDLTWYQYHSLD---VIGFLLAIVLTVVFIV 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	GT1_Gtf-like	26..454	CDD:340817	111/479 (23%)
Ugt1a6b	NP_958812.3	UDPGT	27..522	CDD:278624	130/530 (25%)