Protein Alignment Ugt304A1 and Ugt1a5

DIOPT Version :9

• Sequence 1: NP_652619.1
• Gene: Ugt304A1 / 53501
• FlyBaseID: FBgn0040250
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_964005.2
• Gene: Ugt1a5 / 394433
• MGIID: 3032634
• Length: 529
• Species: Mus musculus
• Alignment Length: 519
• Identity: 130/519 - (25%)
• Similarity: 243/519 - (46%)
• Gaps: 60/519 - (11%)

  Fly    14 LISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIHAYKHCMHKIEDVTFIRIW 78
            |:..::.|....::||.....||  .:.:...::.|..:|||..|:....:...|.||....:::
Mouse    14 LLLCALPWTEGEKVLVFPVGGSH--WLSMRDVVRELHAQGHQTVVLAPEVNMRIKEEDFFTFKVY 76

  Fly    79 ---YNNNVFLEFEESVGIASANNKW--------EEISSMSSLMANATLNVLNNVEVRALMKSRIT 132
               |......|..|::.:......:        |.:.:||:::.....|:|:|..:...:.|. :
Mouse    77 AVPYTRQELEEMMENLKVFFDTGNYMKKIFKTSEALRNMSTVLLKTCTNILHNESLLHHLNSS-S 140

  Fly   133 FDAVVLEAGYSDVLYGMAAHFSAQLIGI--------CTCVADWNINNLVGFSTSTLTEPIMPFRA 189
            ||.|     ::|.::...| ..|:.:||        ..|..::....             .|..:
Mouse   141 FDVV-----FTDPVFPCGA-LLAKYLGIPAVFFLRYIPCGIEYEATQ-------------CPSPS 186

  Fly   190 KYVKNVW----------DRIYNWLYTTEEWLLINLVFLPKQRLIHDHFFGHLEKSFHEIRQDFAL 244
            .|:.|::          .|:.|.||......:.:|:..|.:.|..:.|  ..|.|..|:....::
Mouse   187 SYIPNLFTRLSDHMDFLQRVQNMLYHLVLKYICHLLITPYESLASELF--QREVSSVELFSYASV 249

  Fly   245 MLLNQHFSLFRARPNVPGMVEVAGLHIPKEDPQLPSDLQVFID-EAEHGVILFSLGLEQDSKDLP 308
            .|....|.|...||.:|.||.:.|::...:.| |..:.:.::: ..|||:::||||  ....::|
Mouse   250 WLFRGDFVLDYPRPIMPNMVFIGGINCVTKKP-LSQEFEAYVNASGEHGIVVFSLG--SMVSEIP 311

  Fly   309 RKTQEILVETFKSVPQRVIWKFDGESTMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIE 373
            .|....:.|....:||.|:|::.|....:|..:....|.|||..:|.||..:.||:|.|...:.|
Mouse   312 EKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYE 376

  Fly   374 AAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQ 438
            ......|::.:|.|.||..|.:.|:..|..:.||:..:|..:|::|:.::||...|:|:.:.:|.
Mouse   377 GICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSS 441

  Fly   439 RFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLV 502
            ..:|:||.|||.|::|.||::|:|||.|::.:...|..:.|:|||   ::|..|::|:.:||:|
Mouse   442 LHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLD---VIGFLLAIVLTVVFIV 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	120/495 (24%)
		YjiC	42..445	CDD:224732	99/432 (23%)
Ugt1a5	NP_964005.2	UDPGT	26..520	CDD:278624	128/507 (25%)
		egt	<257..501	CDD:223071	79/249 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840635
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.690