DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt304A1 and Ugt301D1

DIOPT Version :9

Sequence 1:	NP_652619.1	Gene:	Ugt304A1 / 53501	FlyBaseID:	FBgn0040250	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	522	Identity:	169/522 - (32%)
Similarity:	276/522 - (52%)	Gaps:	49/522 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 CWI-----------RSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVI--HAYKHCMHKIED 71
            ||:           ..||||.:.||.:.|..:.:..:...|..:||.:|.:  |..|| .|  |:
  Fly     9 CWMLIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKH-PH--EN 70

  Fly    72 VTFIRI---------WYNNNVF-LEFEESVGIASANN--KWEEISSMSSLMANATLNVLNNVEVR 124
            :|.|.|         :...|:| ::|     ::..||  .|..|..|:      |.:...:.:|:
  Fly    71 LTEIIISPSFDIPKHFPKENIFSMQF-----VSDFNNLELWWTIGLMT------TEHAFKDPKVK 124

  Fly   125 ALMKSRIT-FDAVVLEAGYSDVLYGMAAHFSAQLIGICTCVADWNINNLVGFSTSTLTEPIMPFR 188
            .|::|:.. :|.|::|..:.:........|:..::.|.|.....||::.:|..|.....|.:...
  Fly   125 KLIESKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLS 189

  Fly   189 AKYVKNVWDRIYNWLYTTEEWLLINLVFLPK-QRLIHDHFFGHLE---KSFHEIRQDFALMLLNQ 249
            .........|.||...:..:.::...|:||| |:|...:|.|.:|   .:..::.::.:|:|:|.
  Fly   190 HTDRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINA 254

  Fly   250 HFSLFRARPNVPGMVEVAGLHIPKEDPQLPSDLQVFIDEAEHGVILFSLGLEQDSKDLPRKTQEI 314
            |.|:...||::||:::|.|.||.| ..|||:|||.|:|.|.:|||.||:|....|.|||::...:
  Fly   255 HRSIDLPRPSMPGLIDVGGAHIQK-PKQLPTDLQNFLDNATYGVIYFSMGSYVKSTDLPQEKTAL 318

  Fly   315 LVETFKSVPQRVIWKFDGESTMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAK 379
            :::.|..:.|:|||||:.:|...|.:::...|.:||..|||||||||||:|.|:....|..|:..
  Fly   319 ILKAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGV 383

  Fly   380 PVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQP 444
            |:|.:|.:.||.||......||.|..|..:.||..:|...|.::||:|:|:.|||.:||||||.|
  Fly   384 PMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNP 448

  Fly   445 IHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLD--NFIMVGSRLSLVVALVFLVLSKSR 507
            |||||.|.:|.|||||::||.|:|...:.:.|..|..||  ..:::|:  .|.:.|.:.::.:..
  Fly   449 IHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLLLGA--FLAIWLPWRMIRRVH 511

  Fly   508 RW 509
            :|
  Fly   512 KW 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	162/489 (33%)
Ugt304A1	NP_652619.1	YjiC	42..445	CDD:224732	135/421 (32%)
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	160/485 (33%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	154/460 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	8	7.860