DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt304A1 and F10D2.8

DIOPT Version :9

Sequence 1:	NP_652619.1	Gene:	Ugt304A1 / 53501	FlyBaseID:	FBgn0040250	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001309630.1	Gene:	F10D2.8 / 266913	WormBaseID:	WBGene00017334	Length:	494	Species:	Caenorhabditis elegans

Alignment Length:	532	Identity:	120/532 - (22%)
Similarity:	223/532 - (41%)	Gaps:	70/532 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 FWLISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQL-----TVIHAYKHCMHK--I 69
            |.:|.:.|....|...||..|...||..........||.|.||.:     |::..|::..:.  .
Worm     4 FLVILSLIYSTYSYNFLVFCPLFGHSHTKFFATIADALTDAGHNVTFFTPTIVEKYRNVSYTKLT 68

  Fly    70 EDVTFIRIWYNNNVFLEFEESVGIASANNKWEEISSMSSLMANATLNVLNNVEVRALMKSRITFD 134
            :||..:..   ....:|:.|.:..|..:..|.|.||..::.|......  ::.:..|.||.:.:
Worm    69 KDVVHMDA---PKKLMEYGEQMESADFSRFWTEDSSFYNVGAADLYRC--SIRLNGLFKSLMDY- 127

  Fly   135 AVVLEAGYSDVLYGMAAHFSAQLIGICTCVADWNINNLVGFSTSTLTEPIMPFRAKYVKNVWDRI 199
                                   :.|.|.:...::.:.| :.:..:.||:||   ..|.:|....
Worm   128 -----------------------LNIKTFIPSLSLTHDV-YLSKAIGEPVMP---SVVSDVCSPF 165

  Fly   200 YNWLYTTEEWLLINLVFLPKQRL-----IHDHFFG-HLEKSFHEIRQDFALMLLNQHFSLFRARP 258
            .:.|...|.  ..|...:|...:     :|:.... :.|.....|..:.:.:.||.:..|...||
Worm   166 GDKLSLLER--AFNAFAVPYIDIVLGYPVHNTLSAPYTEIDIRTIEPEASFLFLNSNPFLDFPRP 228

  Fly   259 NVPGMVEVAGLHI---PKEDPQLPSDLQVFIDEAEHGVILFSLGLEQDSKDLPRKTQEILVET-- 318
            .:...||:.|:.:   ..:..||.|.....::..|. .:|.|.|....|||:|.:.::::..:
Worm   229 TLTKTVEIGGITVDLNQLKSQQLDSKWSDILNLREK-TMLVSFGSVFFSKDMPLENKKVIANSMT 292

  Fly   319 -FKSVPQRVIWKFDGESTMSLG---TDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAK 379
             ||:|  ..|||::|.......   .:|:..|.:||.|:||:..:..|.:|.|:.|:.|.:|..|
Worm   293 EFKNV--TFIWKYEGNDIEDFARGIQNIHFVKWVPQTALLANRRLSAFFTHAGLGSINEVSYLGK 355

  Fly   380 PVLGLPSFFDQFRNLEIMKEEGVALELNINSL-TVKELKDAIHSMINEPEYRESALAISQRFRDQ 443
            |.:..|.|.||.||.:::.....::||:...| ..|::.:|..:::.:..|.|:|..::::..:|
Worm   356 PSILCPLFADQMRNAKMLVRHNGSIELSKYDLGNSKKIIEAFQAILFDSSYAENAQKLAEQLENQ 420

  Fly   444 PIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLVLSK--- 505
            ||.|....:...|:..|:.....:.....::...:|:.||    |.:...||:|.|..||::
Worm   421 PIKPEKMMVKHAEFAARFGRLPSLDPYSRKMSFVEYFLLD----VATICVLVLACVVFVLTRVVQ 481

  Fly   506 --SRRWLNHLST 515
              .||:|..:.|
Worm   482 FLCRRFLVKIKT 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	106/490 (22%)
Ugt304A1	NP_652619.1	YjiC	42..445	CDD:224732	92/425 (22%)
F10D2.8	NP_001309630.1	UDPGT	29..492	CDD:278624	111/504 (22%)
F10D2.8	NP_001309630.1	Glycosyltransferase_GTB_type	<215..461	CDD:299143	64/252 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810