Protein Alignment Ugt304A1 and Ugt2b

DIOPT Version :10

• Sequence 1: NP_652619.1
• Gene: Ugt304A1 / 53501
• FlyBaseID: FBgn0040250
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_113721.5
• Gene: Ugt2b / 24862
• RGDID: 3936
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 573
• Identity: 141/573 - (24%)
• Similarity: 247/573 - (43%)
• Gaps: 137/573 - (23%)

  Fly     4 PGRWLLPMFWLISNSICWIRSSRI--LVIAPFESHSQCMLVTPYIQALKDRGHQLTVI--HAYKH 64
            |.:|:..:| |:..|.|: :|...  :::.|.: .|..|.:...:..|..|||::||:  .||
  Rat     2 PRKWISALF-LLQISYCF-KSGHCGKVLVWPMD-FSHWMNIKIILDELVQRGHEVTVLKPSAY-- 61

  Fly    65 CMHKIEDVTFIRIWYNNNVFLEFEESVGIASANNKWEEISSMSSLMANATLNVLNNVEVRALMKS 129
                              .||:.::     |::.|:|..|:      :.:.:.|.|..::.|
  Rat    62 ------------------FFLDPKK-----SSDLKFEIFST------SISKDELQNHFIKLL--- 94

  Fly   130 RITFDAVVLE------AGYSDVLYGMAAHFSAQLIGIC--------------------------- 161
                |....|      ..||.:|..:...||...:.||
  Rat    95 ----DVWTYELPRDTCLSYSPILQNLVYEFSYFYLSICKDAVSNKQLMTKLQESKFDVLFADPVA 155

  Fly   162 TC---VAD-WNINNLVGFSTS-------TLTEPIMPFRAKYVKNVW----------DRIYN---- 201
            :|   :|: .:|..|...|.|       ::.:.|:|  ..||..:.          ||:.|
  Rat   156 SCGDLIAELLHIPFLYSLSFSPGHKLEKSIGKFILP--PSYVPVILSGLAGKMTFIDRVKNMICM 218

  Fly   202 -----W--LYTTEEWLLINLVFLPKQRLIHDHFFGHL---EKSFHEIRQDFALMLLNQHFSLFRA 256
                 |  :...:||               |.|:..:   ..:..|......:.|:..::.|...
  Rat   219 LYFDFWFEILRHKEW---------------DTFYSEILGRPTTVDETMSKVEIWLIRSYWDLKFP 268

  Fly   257 RPNVPGMVEVAGLHIPKEDPQLPSDLQVFIDEA-EHGVILFSLGLEQDSKDLPRKTQEILVETFK 320
            .|.:|.:..:.|||.....| ||.|::.|:..: ||||::||||  ....::..:....:.....
  Rat   269 HPTLPNVDYIGGLHCKPAKP-LPKDMEEFVQSSGEHGVVVFSLG--SMVSNMTEEKANAIAWALA 330

  Fly   321 SVPQRVIWKFDGESTMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLP 385
            .:||:|:|||||::..:||.:....|.|||..||.||..|.|::|.|...:.||.|:..|::|:|
  Rat   331 QIPQKVLWKFDGKTPATLGPNTRVYKWLPQNDILGHPKTKAFVTHGGANGLYEAIYHGIPMIGIP 395

  Fly   386 SFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDA 450
            .|.||..|:..|..:|.|:.|||.:::..:...|:..:|:.|.|:::.:.:|....|||:.|||.
  Rat   396 LFGDQPDNIAHMVAKGAAVSLNIRTMSKLDFLSALEEVIDNPFYKKNVMLLSTIHHDQPMKPLDR 460

  Fly   451 AIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLVL 503
            |::|.|:|:|:|||.|::.....|..:.|:|||   ::|..|:....:..|.:
  Rat   461 AVFWIEFIMRHKGAKHLRPLGHNLPWYQYHSLD---VIGFLLTCFAVIAALTV 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	GT1_Gtf-like	26..454	CDD:340817	118/500 (24%)
Ugt2b	NP_113721.5	UDPGT	24..527	CDD:278624	134/549 (24%)