Protein Alignment Ugt304A1 and Ugt2b5

DIOPT Version :10

• Sequence 1: NP_652619.1
• Gene: Ugt304A1 / 53501
• FlyBaseID: FBgn0040250
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_033493.3
• Gene: Ugt2b5 / 22238
• MGIID: 98900
• Length: 530
• Species: Mus musculus
• Alignment Length: 566
• Identity: 143/566 - (25%)
• Similarity: 243/566 - (42%)
• Gaps: 127/566 - (22%)

  Fly     4 PGRWLLPMFWLISNSICW--IRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIH--AYKH 64
            ||:|:..:. |:..|.|:  ::..::|| .|.| .|..|.:...:..|..|||::||:.  ||
Mouse     2 PGKWISALL-LLQISCCFRSVKCGKVLV-WPME-FSHWMNIKIILDELVQRGHEVTVLRPSAY-- 61

  Fly    65 CMHKIEDVTFIRIWYNNNVFLEFEESVGIASANNKWEEISSMSSLMANATLNVLNNVEVRALMKS 129
                              ..|:.::|.|:     |:|...:..| ..|.....:..|:|......
Mouse    62 ------------------YVLDPKKSPGL-----KFETFPTSVS-KDNLENFFIKFVDVWTYEMP 102

  Fly   130 RITFDAVVLEAGYSDVLYGMAAHFSAQLIGICTCVADWNINNLVGFSTS----TLTEPI------ 184
            |.|.      ..||.:|..|...||...:.:|..|.. |...:.....|    .|::|:
Mouse   103 RDTC------LSYSPLLQNMIDEFSDYFLSLCKDVVS-NKELMTKLQESKFDVLLSDPVASCGEL 160

  Fly   185 ------MPF---------------------RAKYVKNVW----------DRIYN---------W- 202
                  :||                     ...||..:.          :||.|         |
Mouse   161 IAELLQIPFLYSIRFSPGYQIEKSSGRFLLPPSYVPVILSGLGGQMTFIERIKNMICMLYFDFWF 225

  Fly   203 -LYTTEEWLLINLVFLPKQRLIHDHFFGHL---EKSFHEIRQDFALMLLNQHFSLFRARPNVPGM 263
             ::..::|               |.|:...   ..:..|......:.|:..::.|....|.:|.:
Mouse   226 QMFNDKKW---------------DSFYSEYLGRPTTLVETMGQAEMWLIRSNWDLEFPHPTLPNV 275

  Fly   264 VEVAGLHIPKEDPQLPSDLQVFIDEA-EHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQRVI 327
            ..|.|||.....| ||.|::.|:..: :|||::||||  ....::..:....:......:||:|:
Mouse   276 DYVGGLHCKPAKP-LPKDMEEFVQSSGDHGVVVFSLG--SMVSNMTEEKANAIAWALAQIPQKVL 337

  Fly   328 WKFDGESTMSLG--TDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQ 390
            |||||::..:||  |.:|  |.|||..:|.||..|.|::|.|...|.||.|:..|::|:|.|.:|
Mouse   338 WKFDGKTPATLGHNTRVY--KWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPLFGEQ 400

  Fly   391 FRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWT 455
            ..|:..|..:|.|:.|||.:::..::.:|:..:|..|.|:::|:.:|....|||:.|||.|::|.
Mouse   401 HDNIAHMVAKGAAVALNIRTMSKSDVLNALEEVIENPFYKKNAMWLSTIHHDQPMKPLDRAVFWI 465

  Fly   456 EYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFL 501
            |:::|:|.|.|::.....|..:.|:|||   ::|..||.|...:.|
Mouse   466 EFVMRHKRAKHLRPLGHNLTWYQYHSLD---VIGFLLSCVATTIVL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	GT1_Gtf-like	26..454	CDD:340817	121/493 (25%)
Ugt2b5	NP_033493.3	UDPGT	24..527	CDD:278624	137/543 (25%)