DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt304A1 and ugt-37

DIOPT Version :9

Sequence 1:	NP_652619.1	Gene:	Ugt304A1 / 53501	FlyBaseID:	FBgn0040250	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_504811.2	Gene:	ugt-37 / 184293	WormBaseID:	WBGene00017332	Length:	528	Species:	Caenorhabditis elegans

Alignment Length:	543	Identity:	120/543 - (22%)
Similarity:	232/543 - (42%)	Gaps:	83/543 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SSRILVIAPFESHSQCMLVTPYIQALKDRGHQL-----TVIHAY---------KHCMH------- 67
            |...|:.:|...||...........|.:.||.:     |:|..:         ||.:|
Worm    16 SYNFLIFSPLFGHSHTTFFAKIADTLSEAGHNVTFFTPTIIRKFSKINYVKHTKHVIHLEPSEKL 80

  Fly    68 -----KIEDVTFIRIWYNNNVFLEFEESVGIASANNKWEEISSMSSLMANATLNVLNNVEVRALM 127
                 ::|||...|.|.:::...|....:.:      :.|:.:..:.:....|:||:.::
Worm    81 ERYGNQMEDVDISRFWTDDSSMAEMFPMIKL------FNEMFAEQAFVLGQNLDVLDELK----- 134

  Fly   128 KSRITFDAVVLEAGYSDVLYGMAAHFSAQ-LIGICTCVADWNINNLVGFS--TSTLTEPIMPFRA 189
              .:.||.::.|. :::..|.:..:...: .|...:.:.|.|:...:|..  .||:..|:..|..
Worm   135 --EMKFDVMIFER-FAECAYPLLEYLEIETFIPSSSLLFDPNLLISIGEPRIPSTVPLPMSKFTD 196

  Fly   190 KYVKNVWDRIYNWLYTTEEWLLINLVFLPKQRLIHDHFFGHLEKSFHEIRQDFALMLLNQHFSLF 254
            |            :..||.  |:|.:.:|   :.|.....|..|||....|...:..: :|.|.|
Worm   197 K------------MTMTER--LLNAIAVP---IFHSLLPTHEFKSFRPPYQAIDIQKM-EHLSSF 243

  Fly   255 ----------RARPNVPGMVEVAGLHIPKEDPQLPSDLQVF--IDEAEHGVILFSLGLEQDSKDL 307
                      ..||.:...|::.|:.:..|:.::....:.:  |.:.....||.|.|....|||:
Worm   244 ILSNSNPYIDYPRPTLEKNVQIGGISVDVENLKIHKVNEEWDRILDMRQKTILVSFGSVMLSKDM 308

  Fly   308 PRKTQEILVETFKSVPQ-RVIWKFDGEST---MSLGTDIYHSKLLPQQAILAHPNVKLFISHCGM 368
            |.:.::||.:|.|..|: ..|||::...|   .|...:|:.|..:||.|:||...:..|.:|.|:
Worm   309 PVENKKILAKTMKQFPEVTFIWKYEFNDTDLFASETENIHFSSWVPQTALLADRRLTAFFTHAGL 373

  Fly   369 MSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSL-TVKELKDAIHSMINEPEYRES 432
            .||.|.:|..||.:..|.|.||.||.:::.....::|::...| ..::::..:.:::.:..||.|
Worm   374 GSVNEVSYLGKPSIMCPIFADQMRNAKMLARHNGSIEISKYDLGNGEKIEKTLRTILFDDSYRLS 438

  Fly   433 ALAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLD-NFIMVGSRLSLVV 496
            |..::.:..:||:.|.:..:...|:..::.....:.....||...:|:.:| ..|::.|.|.:||
Worm   439 AEKLAHQLANQPVKPKELLLRHAEFAAQFGRLPSLDPYSRQLSFVEYFLIDVAAILIFSSLLIVV 503

  Fly   497 ALVFLVLSKSRRWLNHLSTSAKS 519
            .|..::    :|.:|.|..:..|
Worm   504 VLFQII----KRLINFLPVTVDS 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	108/501 (22%)
Ugt304A1	NP_652619.1	YjiC	42..445	CDD:224732	98/448 (22%)
ugt-37	NP_504811.2	Glycosyltransferase_GTB_type	1..504	CDD:299143	114/519 (22%)
ugt-37	NP_504811.2	UDPGT	37..510	CDD:278624	111/508 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810