DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt304A1 and ugt-7

DIOPT Version :9

Sequence 1:	NP_652619.1	Gene:	Ugt304A1 / 53501	FlyBaseID:	FBgn0040250	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_504343.2	Gene:	ugt-7 / 182577	WormBaseID:	WBGene00015739	Length:	530	Species:	Caenorhabditis elegans

Alignment Length:	544	Identity:	126/544 - (23%)
Similarity:	230/544 - (42%)	Gaps:	85/544 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIHAYKHCMHKIEDVTFIR------IWYN-NNV 83
            :.|:|:|..|:|....::.....|.|.||::.|..  :..:..:.|...|:      |.|. |..
Worm    17 KYLIISPIYSYSHVKFMSNIADTLADHGHEVVVFQ--QQIVEALRDKKVIKNPDIKIINYEANTA 79

  Fly    84 FLEFEESVGIASANNKW------------EEISSMSSLMANATLNVLNNVEVRALMKSRITFDAV 136
            ..||..:...:|....|            :...:||..:.:..|.|..:..:..::||. .||.:
Worm    80 GKEFYRNRPKSSVTKYWTTNQAANPSAADQFAEAMSKDLEHMCLQVFEDKSLHTMLKSE-HFDVL 143

  Fly   137 VLEAGYSDVLY-GMAAHFSAQLIGICTCVAD---WNINNLVGFSTSTLTEPIMPF-RAKY--VKN 194
            :.|......|| |......:.::.:.:...|   |.:....|.:       .:|. .:||  ...
Worm   144 LAEPFDPCGLYLGDYLKIPSTIVAMASSRIDPVQWALGQPSGLN-------FIPGPDSKYGEESG 201

  Fly   195 VWDRIYN-WLYTTEEWLLINLVFLPKQRLIHDHFFGHLEK----------SFHEIRQDFALMLLN 248
            |||||.| |:            |..:.|:....::..|:|          :..||..:.|.:..|
Worm   202 VWDRINNVWM------------FFMRTRMFRAVYWNLLDKLRFKTGLEIRNIDEIVAESAYLFYN 254

  Fly   249 QHFSLFRARPNVPGMVEVAGLHIPK---EDPQLPSDLQVFIDEAEHGVILFSLGLEQDSKDLPRK 310
            .:..|....|::...|.:.|..:..   :...||.:|:..:.:..:.|.: |.|....|.|:|::
Worm   255 SNPYLDFPFPSLTKCVPIGGFSMNTTNWKSENLPENLKNILQKRPNTVFI-SFGSVIRSADMPQE 318

  Fly   311 TQEILVETFKSVPQ-RVIWKF----DGESTMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMS 370
            .:..::|..|.:.. ..|||:    |.|...::..:::..|.|||.|:||...|.|||:|.|:.|
Worm   319 YKNAIIEVTKLMSDVTFIWKYEDEKDEEMRGNIPENVHLMKWLPQPALLADSRVSLFITHGGLGS 383

  Fly   371 VIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVA-----LELNINSLTVKELKDAIHSMINEPEYR 430
            ::|.||..||.:.:|.||||..|.|:::..|.|     .||:    ..|:||..|.:||..|:|.
Worm   384 IMEVAYSGKPAIVIPLFFDQPMNGEMLRRHGGAEVYSKFELS----NAKKLKKVIQNMIQNPKYL 444

  Fly   431 ESALAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLV 495
            .:|..:|...:.|||:|::..:...|:...:|....:......|..|.::.||        :...
Worm   445 ANAKKLSNLLQKQPINPIERLVKHAEFAAEFKKLPELDPYSRHLNFFQFFFLD--------IVAT 501

  Fly   496 VALVFLVLSKSRRWLNHLSTSAKS 519
            :.::|::.:....|:.::..|.:|
Worm   502 LLILFMLSALFVYWITYVICSVRS 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	120/503 (24%)
Ugt304A1	NP_652619.1	YjiC	42..445	CDD:224732	108/452 (24%)
ugt-7	NP_504343.2	egt	1..477	CDD:223071	117/486 (24%)
ugt-7	NP_504343.2	UDPGT	27..521	CDD:278624	120/528 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810