DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt304A1 and ugt-50

DIOPT Version :9

Sequence 1:	NP_652619.1	Gene:	Ugt304A1 / 53501	FlyBaseID:	FBgn0040250	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_741913.1	Gene:	ugt-50 / 181413	WormBaseID:	WBGene00011564	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	557	Identity:	132/557 - (23%)
Similarity:	240/557 - (43%)	Gaps:	105/557 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RWLLPMFWLISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTV-IHAYKHCMHKI 69
            ||:......:.:....:.:::|||..|..|.|..:|.:.|...|.:.||...: |.:|...:...
Worm     7 RWMFFCLTALLHGSFIVNAAKILVYCPSISKSHVLLCSKYADLLHNAGHDTVLFIPSYSKLLDNY 71

  Fly    70 EDVTFIRIWYNNNVFLEFEESVGIASANNKWEEISSMSSLMANATLNVLNNVEVRALMKSRITFD 134
            :.....::|..:||...::..:|            :::::|.|:.:..::          |:|||
Worm    72 DGAKHAKVWRLHNVTEAYDTKLG------------TLANVMENSHIGFID----------RLTFD 114

  Fly   135 AVVLEAGYSDVLYGMAAHFSAQL------------------IGICT--CVADWNINNLVGFSTST 179
            |        |....|.|....:|                  |..||  .|..:||...|..|:..
Worm   115 A--------DFWIDMCADLLGKLPEMQHIIDYKFDLVIYNEIDPCTPAIVRLFNIPKTVLLSSEA 171

  Fly   180 LTEPI-----MPFRAKYVKNV-----WDR---------IYNWLYTTEEWLL--INLVFLPKQRLI 223
            :.:.:     :|....||.:|     .||         :|.:..:.....|  |:::.|.::.:.
Worm   172 IMDKVAWNLGLPTLPSYVPSVEENPNHDRMSFFERMSNVYKFFQSIVVHYLQDIHVLNLFRKEVS 236

  Fly   224 HDHFFGHLEKSFHEIRQDFALMLLN--QHFSLFRARPN---VPGMVEVAGLHIPKEDPQLPSDLQ 283
            .|.      .|..||.::.:|:|:|  :.|.|.|:..:   ..||:| ||   ..|:..||....
Worm   237 SDF------PSIAEIIRNVSLVLVNTDEIFDLPRSYSSKFVYVGMLE-AG---KDENVTLPKKQD 291

  Fly   284 VFIDEAEHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQRVIWKF------DGESTMSLGTDI 342
            .:..:.:.|.:..|.|.....:.||.:.|..::...:.:|.   :.|      |.||:....:.:
Worm   292 DYFKKGKSGSVFVSFGTVTPFRSLPERIQLSILNAIQKLPD---YHFVVKTTADDESSAQFFSTV 353

  Fly   343 YHSKL---LPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVAL 404
            .:..|   :||:|:|.|.|:|||:||.||.||:|..||..|::.:|.|.|||||...::..| |.
Worm   354 QNVDLVDWVPQKAVLRHANLKLFVSHGGMNSVLETMYYGVPMVIMPVFTDQFRNGRNVERRG-AG 417

  Fly   405 ELNINSLTVKE-LKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMK 468
            ::.:....||| ..|||||::.|..|..|...||...:::|....:....|.:::::|:.::|..
Worm   418 KMVLRETVVKETFFDAIHSVLEEKSYSSSVKRISHLMKNKPFTSEERVTKWIDFVLKYETSEHFD 482

  Fly   469 ISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLVLSK 505
            :..:.|.:.::..||.|..    |.::..|.|:|..|
Worm   483 LESNNLSIIEHNHLDLFFY----LCIISLLNFVVYRK 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	122/528 (23%)
Ugt304A1	NP_652619.1	YjiC	42..445	CDD:224732	110/459 (24%)
ugt-50	NP_741913.1	egt	9..475	CDD:223071	119/509 (23%)
ugt-50	NP_741913.1	UDPGT	26..520	CDD:278624	130/538 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810