Protein Alignment Ugt304A1 and UGT3A1

DIOPT Version :9

• Sequence 1: NP_652619.1
• Gene: Ugt304A1 / 53501
• FlyBaseID: FBgn0040250
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_689617.3
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 523
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 128/534 - (23%)
• Similarity: 237/534 - (44%)
• Gaps: 53/534 - (9%)

  Fly     6 RWLLPMFWLISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIH-AYKHCMHKI 69
            |.||.:.:|:| .:....:::||.|:.. ..|..:|:....|.|::.||.:|::| :.|..:..|
Human     5 RVLLLVAFLLS-GVLLSEAAKILTISTL-GGSHYLLLDRVSQILQEHGHNVTMLHQSGKFLIPDI 67

  Fly    70 ED----VTFIRIWYN-----NNVFLEFEESVGIASANNKWEE-ISSMSSLMANATLNVLNNVEVR 124
            ::    ...|| |::     ..:...|:..:..|....|..| :..:..:.......:|:..::.
Human    68 KEEEKSYQVIR-WFSPEDHQKRIKKHFDSYIETALDGRKESEALVKLMEIFGTQCSYLLSRKDIM 131

  Fly   125 ALMKSRITFDAVVLEAGYSDVLYGMAAHFSAQ-LIGICTCVADWNINNL-VGFSTSTLTEPIMPF 187
            ..:|:. .:|.|.:||      :...:...|: |:.....:......:| .|..:.....|:.|.
Human   132 DSLKNE-NYDLVFVEA------FDFCSFLIAEKLVKPFVAILPTTFGSLDFGLPSPLSYVPVFPS 189

  Fly   188 RAKYVKNVWDRIYNWL----YTTEEWLLINLVFLPKQRLIHDHFFGHLEKSFHEIRQDFALMLLN 248
            ......:.|.|:.|:|    ::..:|.:.:..    ...|.:||..........:.....|..:|
Human   190 LLTDHMDFWGRVKNFLMFFSFSRSQWDMQSTF----DNTIKEHFPEGSRPVLSHLLLKAELWFVN 250

  Fly   249 QHFSLFRARPNVPGMVEVAGLHIPKEDPQLPSDLQVFI-DEAEHGVILFSLGLEQDSKDLPRKTQ 312
            ..|:...|||.:|..|.:.|| :.|....:|.||..|| :..:.|.:|.:.|...::    .::|
Human   251 SDFAFDFARPLLPNTVYIGGL-MEKPIKPVPQDLDNFIANFGDAGFVLVAFGSMLNT----HQSQ 310

  Fly   313 EILVE---TFKSVPQRVIWKFDGE---STMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSV 371
            |:|.:   .|..:||.|||.....   ..:.|.|::.....|||..:||||:::||::|.|..||
Human   311 EVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHLATNVKIVDWLPQSDLLAHPSIRLFVTHGGQNSV 375

  Fly   372 IEAAYYAKPVLGLPSFFDQFRNL--EIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESAL 434
            :||..:..|::|||...||..|:  .:.|..||::.|  |.:|...|...:..:|.:..|:.:.:
Human   376 MEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRL--NQVTADTLTLTMKQVIEDKRYKSAVV 438

  Fly   435 AISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALV 499
            |.|.....||:.|....:.|.::|::..||.|:|....|....:.|.:|.|:.:   |.|.:..:
Human   439 AASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQPWHEQYLIDVFVFL---LGLTLGTM 500

  Fly   500 FL---VLSKSRRWL 510
            :|   :|....|||
Human   501 WLCGKLLGVVARWL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	117/497 (24%)
		YjiC	42..445	CDD:224732	99/428 (23%)
UGT3A1	NP_689617.3	UDPGT	23..523	CDD:330975	123/515 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150070
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740