Protein Alignment Ugt304A1 and UGT2A1

DIOPT Version :10

• Sequence 1: NP_652619.1
• Gene: Ugt304A1 / 53501
• FlyBaseID: FBgn0040250
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001376494.1
• Gene: UGT2A1 / 10941
• HGNCID: 12542
• Length: 737
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 92/261 - (35%)
• Similarity: 157/261 - (60%)
• Gaps: 7/261 - (2%)

  Fly   244 LMLLNQHFSLFRARPNVPGMVEVAGLHIPKEDPQLPSDLQVFIDEA-EHGVILFSLGLEQDSKDL 307
            :.|:..::.....||.:|....|.|||.....| ||.:::.||..: ::||::||||  ...|:|
Human   463 IWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKP-LPKEMEEFIQSSGKNGVVVFSLG--SMVKNL 524

  Fly   308 PRKTQEILVETFKSVPQRVIWKFDGESTMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVI 372
            ..:...::......:||:|:|::.|:...:||.:......:||..:|.||..|.||:|.|...:.
Human   525 TEEKANLIASALAQIPQKVLWRYKGKKPATLGNNTQLFDWIPQNDLLGHPKTKAFITHGGTNGIY 589

  Fly   373 EAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAIS 437
            ||.|:..|::|:|.|.||..|:..||.:|.|:|:|:|::|..:|..|:.::||||.|:|:|:.:|
Human   590 EAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNLNTMTSVDLLSALRTVINEPSYKENAMRLS 654

  Fly   438 QRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLV 502
            :...|||:.|||.|::|.|:::|:|||.|::::...|..|.|:|||   ::|..|..|...:|||
Human   655 RIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLD---VIGFLLVCVTTAIFLV 716

  Fly   503 L 503
            :
Human   717 I 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	GT1_Gtf-like	26..454	CDD:340817	73/210 (35%)
UGT2A1	NP_001376494.1	UDPGT	237..725	CDD:278624	92/261 (35%)