Protein Alignment Ugt304A1 and UGT2A1

DIOPT Version :9

• Sequence 1: NP_652619.1
• Gene: Ugt304A1 / 53501
• FlyBaseID: FBgn0040250
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001376494.1
• Gene: UGT2A1 / 10941
• HGNCID: 12542
• Length: 737
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 92/261 - (35%)
• Similarity: 157/261 - (60%)
• Gaps: 7/261 - (2%)

  Fly   244 LMLLNQHFSLFRARPNVPGMVEVAGLHIPKEDPQLPSDLQVFIDEA-EHGVILFSLGLEQDSKDL 307
            :.|:..::.....||.:|....|.|||.....| ||.:::.||..: ::||::||||  ...|:|
Human   463 IWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKP-LPKEMEEFIQSSGKNGVVVFSLG--SMVKNL 524

  Fly   308 PRKTQEILVETFKSVPQRVIWKFDGESTMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVI 372
            ..:...::......:||:|:|::.|:...:||.:......:||..:|.||..|.||:|.|...:.
Human   525 TEEKANLIASALAQIPQKVLWRYKGKKPATLGNNTQLFDWIPQNDLLGHPKTKAFITHGGTNGIY 589

  Fly   373 EAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAIS 437
            ||.|:..|::|:|.|.||..|:..||.:|.|:|:|:|::|..:|..|:.::||||.|:|:|:.:|
Human   590 EAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNLNTMTSVDLLSALRTVINEPSYKENAMRLS 654

  Fly   438 QRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLV 502
            :...|||:.|||.|::|.|:::|:|||.|::::...|..|.|:|||   ::|..|..|...:|||
Human   655 RIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLD---VIGFLLVCVTTAIFLV 716

  Fly   503 L 503
            :
Human   717 I 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	82/236 (35%)
		YjiC	42..445	CDD:224732	68/201 (34%)
UGT2A1	NP_001376494.1	UDPGT	237..725	CDD:278624	92/261 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150205
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.690