Protein Alignment Ugt304A1 and ugt1a1

DIOPT Version :10

• Sequence 1: NP_652619.1
• Gene: Ugt304A1 / 53501
• FlyBaseID: FBgn0040250
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: XP_004917944.1
• Gene: ugt1a1 / 100489505
• XenbaseID: XB-GENE-998849
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 513
• Identity: 140/513 - (27%)
• Similarity: 256/513 - (49%)
• Gaps: 61/513 - (11%)

  Fly    22 IRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVI--HAYKHCMHKIEDVTFIRIWYNNNVF 84
            |.:.::|.|....||...|.:  .:::|..||:|:.|:  |:..| :|..|:  :|...|.....
 Frog    26 IEAEKLLAIPLDGSHWLSMRI--LVESLGQRGNQVVVLAPHSNIH-IHPSEN--YILRTYPVPYS 85

  Fly    85 LEFEESVGIASAN-------------NKWEEISSMSSLMANATLNVLNNVEV-RALMKSRITFDA 135
            .|..:...:.|||             |.::.|::::.::.:|..::|::.|: :.|.:|  .|||
 Frog    86 KELLKEQMVKSANDVFTKRPLLDKITNMYQRITNVTGIVFSACQHLLHSKEIMQELQES--AFDA 148

  Fly   136 VVLE---------AGYSD-----VLYGMAAHFSAQLIGICTCVADWNINNLVGFSTSTLTEPIMP 186
            .:::         |.|..     :|||:..... :|...|.....:...:..| :|..::.|
 Frog   149 ALIDPFFPCGMIVAEYLHLPSVYLLYGLPCGID-RLATQCPSPLSYVPRHFTG-NTDHMSFP--- 208

  Fly   187 FRAKYVKNVWDRIYNWLYTTEEWLLINLVFLPKQRLIHDHFFGHLEKSFHEIRQDFALMLLNQHF 251
                      .|:.|.|....:..|.||::.|..:|..:  |.|.|.:..::....::.|:...|
 Frog   209 ----------QRLKNALLWPVDTFLCNLLYSPYAQLASE--FLHREMTILQLYSQTSVWLMKTDF 261

  Fly   252 SLFRARPNVPGMVEVAGLHIPKEDPQLPSDLQVFIDEA-EHGVILFSLGLEQDSKDLPRKTQEIL 315
            .....||.:|.||.|.|::...|. .|..:.:..::.: |||.::||||  ....::|......:
 Frog   262 VFDYPRPLMPNMVFVGGINCVGEQ-HLNQEFEKLVNSSGEHGFVVFSLG--SMVSEIPMNKAMDI 323

  Fly   316 VETFKSVPQRVIWKFDGESTMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKP 380
            .|..||:||:|.|::.|::..:||.:.:..|.|||..:||||..:.||:|.|...:.|....|.|
 Frog   324 AEALKSIPQKVFWRYTGKAPPNLGENTHLVKWLPQNDLLAHPKARAFITHAGSHGIYEGICNAVP 388

  Fly   381 VLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPI 445
            ::.:|.|.||..|.:.::..|..|.||:..:|.::|.:|:.::||.|.|:|:...:|....|:||
 Frog   389 MVMMPLFGDQMDNAKRIESRGAGLTLNVLHMTPEDLSNAVRAVINNPVYKENIQRMSSLHLDRPI 453

  Fly   446 HPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLVL 503
            ||||.|::|.|:::|:|||.|::.:...|..|.|||||   ::|..|::::..:|:.|
 Frog   454 HPLDLAVHWVEFVMRHKGAPHLRPAAHDLNWFQYYSLD---VIGFLLAVLLTALFISL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt304A1	NP_652619.1	GT1_Gtf-like	26..454	CDD:340817	121/458 (26%)
ugt1a1	XP_004917944.1	UDPGT	30..525	CDD:278624	139/509 (27%)