Protein Alignment SP1029 and npepps

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_001072690.1
• Gene: npepps / 780147
• XenbaseID: XB-GENE-1008338
• Length: 875
• Species: Xenopus tropicalis
• Alignment Length: 919
• Identity: 289/919 - (31%)
• Similarity: 454/919 - (49%)
• Gaps: 97/919 - (10%)

  Fly    31 YYRLPTSLRPQKYHLRILTLLENPE--DLRFSGSVKILIEALENTKNVTLHSKNLTIDESQITLR 93
            :.||||.:||..|.|.:     .|:  |..|.|.::..:|....|..:.::..::.|    || .
 Frog     7 FERLPTDVRPVNYGLCL-----KPDLIDFTFEGKLEATVEVQNATNQIVMNCADIDI----IT-A 61

  Fly    94 QIGGEGKKENCVSSTAVN-PSHDFYILNTCQELLAGNTYELYMPFAADLNRQLEGYYRSSYKDPV 157
            ....||.:|  :.:|..| .:.|..:..:....|......|.:.|..:||.:::|:|||.|....
 Frog    62 SYAPEGDEE--IHATGFNYQNEDEKVTLSFPSTLQKGAGMLKIDFVGELNDKMKGFYRSKYATAT 124

  Fly   158 ANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHETLADYIW 222
            ..: ::.:|||||...||.||||:|||..||.|.|.|...|...|:|||...:.||:....:.:.
 Frog   125 GEV-RYAAVTQFEATDARRAFPCWDEPAIKATFDVILIVPKDRVALSNMNLIDRKPYPDDENLVE 188

  Fly   223 CEFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRTWARPNAIDQCDYAAQFGPKVLQYYEQFFG 287
            .:|..:..|||||||:.|.::....:...:..|.|.:......:|..:|.:...|.|.:|:.:|.
 Frog   189 VKFARTPIMSTYLVAFVVGEYDFVETRSSDGVLVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFN 253

  Fly   288 IKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQRVASVVAHELAHQWFGNL 352
            :.:||||||.||:.||:||||||||||||||.|||....:|..:.:|.||.||.|||||||||||
 Frog   254 VPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNL 318

  Fly   353 VTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFRRDALESSHPISRPIQMVS 417
            |||:|||.||||||||:::..|.|::..||:....|...::.......||||:||||...:...|
 Frog   319 VTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALENSHPIEVSVGHPS 383

  Fly   418 EISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNLWESLTQAAHKYRSL 482
            |:.|.||.|||.||::|:||:|.::|:|.||.|:..||.||..|||..::|||||.||:.|
 Frog   384 EVDEIFDAISYSKGASVIRMLHDYIGDEDFRKGMNQYLTKFQEKNAATEDLWESLEQASGK---- 444

  Fly   483 PKSYDIKSIMDSWTLQTGYPVINVTRDYAARTA--KLNQERYLLN--TQVARAYRGGCWWVPLSY 543
                .|.::|::||.|.|:|:|.|..:....:.  ||:|:::..:  .....:|:   |.||:|.
 Frog   445 ----PIAAVMNTWTKQMGFPLICVESEQKEDSVVLKLSQKKFCASGAPNSDDSYQ---WMVPISI 502

  Fly   544 TTQAVQDFNNTAPKAWMECGKNGESLPKTIQDLP---------GPDQWVIFNTQLSTLYKVNYDA 599
            .|       :.:|         ..:..|.:.|.|         .|.|||..|......|:..|..
 Frog   503 CT-------SESP---------ASATVKILMDKPEMTVVLEGVKPHQWVKLNPGTVGFYRTQYST 551

  Fly   600 QNWKLLIETLTNG--DFERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQREREYLPWKSA 662
                .::|:|..|  |.. :..::|..|.:|...||..|..:....::::|....|..|..|...
 Frog   552 ----TMLESLLPGIRDLS-LQPVDRLGLQNDLFSLARAGMINTAEVLKVMEAFVNEPNYTVWSDL 611

  Fly   663 FENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHLNGINDTFSAIPQQDQV--LLKTMVVNWACQ 725
            ..||..:..::..|...|..:.:::.:..||.:.|.     :...|.:..:  ||:.:|:.
 Frog   612 SCNLGILSTLLSHTDFHEEIQCFVRDVFSPIGQRLG-----WDPKPGEGHLDALLRGLVLG---- 667

  Fly   726 YQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVYCTSIKHGSDSDWEFLWTRYKKSNVAAE 790
             ::|....|........|.:.:.|.:|.:..::||.||.|.:|||.:|..|.:...:|::::..|
 Frog   668 -KLGKAGHQPTLEEARRRFKEHVDGRNVLSADLRSPVYVTVLKHGDNSTLETMMKLHKQADMQEE 731

  Fly   791 KRTILTALGCSREVWLLQRYLELTFDPKEAIRKQDSMWAFQAVA-FNEVGFLLAKKYFMDNVDFI 854
            |..|...||...|..|:::.  |:|...|.:|.||::.....|| .:::|...|..:..||.:.:
 Frog   732 KNRIERVLGAIAEQDLIKKV--LSFSLSEDVRPQDTVCVIGGVAGGSKLGRKCAWNFVKDNWEEL 794

  Fly   855 YKFYHP--LTKDMSRLLSPLSEQVITLSDF------NEFKDFVNNSRQSLKGLEQAIQQTLEIML 911
            |..|..  |   :|||:.      ::|..|      .|.|.|.:  .......|:.:||..|.:|
 Frog   795 YNRYQGGFL---ISRLIK------LSLDGFASDKMAAEIKAFFD--AHPAPSAERTVQQCCENIL 848

  Fly   912 TNVQWKERN 920
            .|..|.:|:
 Frog   849 LNAGWLKRD 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	178/457 (39%)
		ERAP1_C	582..910	CDD:463368	80/340 (24%)
npepps	NP_001072690.1	M1_APN-Q_like	17..455	CDD:341064	178/458 (39%)
		ERAP1_C	534..847	CDD:463368	80/340 (24%)