Protein Alignment SP1029 and Lvrn

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_083284.1
• Gene: Lvrn / 74574
• MGIID: 1921824
• Length: 991
• Species: Mus musculus
• Alignment Length: 969
• Identity: 288/969 - (29%)
• Similarity: 442/969 - (45%)
• Gaps: 137/969 - (14%)

  Fly    29 YNYYRLPTSLRPQKYHLRILTLLE----NPEDLRFSGSVKILIEALENTKNVTLHS--------- 80
            :::.|||..|.|..|.|.:...|:    :|.:|.|:|.|.|.:.....:..:.|||
Mouse    90 WDHLRLPPWLVPLHYDLELWPWLQPDKLSPPNLTFTGRVNITVRCTVASSRLLLHSFLLNYKQVE 154

  Fly    81 ---------KNLTIDESQITLRQIGGEGKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMP 136
                     :|.|:...|               |......|...|.:|:..|.|..|:.|||...
Mouse   155 VWGPLAQDTRNATVGRVQ---------------VEKVWFAPDMQFVVLDLGQSLEPGSRYELSFH 204

  Fly   137 FAAD-LNRQLEGYYRSSYKDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKY 200
            |:.. |...|||.:.:.|.|  .:..:.:..||.||..||..|||||||..||.|.:|:.:|..|
Mouse   205 FSGQVLQVGLEGLFLNLYHD--EDELRALVATQMEPTFARHVFPCFDEPALKATFNITVIHHPGY 267

  Fly   201 TAISNMPEKETKPHETLADYIW--CEFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRTWARPN 263
            .|:||||:........:....|  ..|..:..|.|||||..|.|..|...|.....: |.|||.:
Mouse   268 AALSNMPQLGQSERIDVNGSRWTVTTFHTTPRMPTYLVALVVCDLDHISRTERGKEI-RVWARKD 331

  Fly   264 --AIDQCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAA 326
              |....|:||.....:..:.|..|.|.:.|||.|.:|:|.|::||||||||:.:.|.:||....
Mouse   332 DIASGYLDFAANITGPIFSFLEDLFNISYRLPKTDIVALPIFASGAMENWGLLIFDESSLLLEPE 396

  Fly   327 HSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESL 391
            ......:..:.|::|||:.||||||||||.||.::|||||||:|   ..:|..|..:..:....:
Mouse   397 DELTEKRAMILSIIAHEVGHQWFGNLVTMSWWNNIWLNEGFASY---FELELTNYFYPKVPMNMI 458

  Fly   392 ---SNLLTIFRRDALESSHPISRPIQ---MVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSG 450
               :.|..|...|....|..:|..::   ..|||:..||..:|:||:.:..|:..||....|.:.
Mouse   459 FFFTVLHGILGEDHALESRAVSTAVENFTETSEINRLFDLYTYKKGACMAWMLASFLSPHLFINA 523

  Fly   451 LQAYLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTA 515
            |::||:.|||.|||||:||..:..|..:.........:|.||||||.:.|:|:|.|.    ..|.
Mouse   524 LKSYLETFSYSNAEQDDLWRHIQMAIGEQNVTHLPATVKGIMDSWTHRGGFPIITVN----VSTG 584

  Fly   516 KLNQERYLLN---TQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDLP 577
            .:.||.:.|:   .|...:: ...|.||:.:....:..     |..|::         |:....|
Mouse   585 VVKQEPFYLDKVENQTLLSH-NSTWIVPIFWMKNGIPQ-----PLVWLD---------KSNMMFP 634

  Fly   578 G------PDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTG 636
            |      ...|||.|..::..|:||||...||.|.|.|.. |.:.|.||||.||:.||..|....
Mouse   635 GMKLSDSDSDWVILNFNVTGYYRVNYDELGWKKLSEQLEK-DPKAIPVINRLQLVSDAFALTKNN 698

  Fly   637 EQDYEIAMRLIEYLQREREYLPWKSAFENL--KRVGRIVRQTPDFEFFKRYMKKLILPIYEHLNG 699
            ..:.|.|:.|.:|:..|.|.|.|.....||  :.|...|.....:...|:|:.|       ..|.
Mouse   699 YIEIETALDLTKYIAEEDEILVWFEVLLNLINREVIYDVNNYALYPLLKKYLLK-------RFNS 756

  Fly   700 INDTFSAIPQQDQVLLK---------TMVVNWACQYQVGDCVPQALAYYRNWRAEANPDEKNPVP 755
            |.:|:|||.:::...|:         ..:...||...:.||:..:...::.|  .|:|:  ..:|
Mouse   757 IWNTYSAIIRENVASLQDNYLSLFSLERIFETACWLGLEDCLQLSRELFKKW--TAHPE--TAIP 817

  Fly   756 INVRSTVYCTSIKHGSDSDWEFLWTRY---KKSNVAAEKRTILTALGCSREVWLLQRYLELTFDP 817
            ..:.:.|.|:::..|||.||:||:..|   .:....:.:|.::.|:.||::.|:|.|::|.
Mouse   818 PQIENAVLCSAVALGSDKDWDFLFNLYINTTEEEDESRRRRLVHAMSCSKDPWILNRFMEY---- 878

  Fly   818 KEAIRKQDSMWA----FQAVAFNEVGFLLAKKYFMDNVDFIYKFY-----HPLTKDMSRLLSPLS 873
              ||....|.::    ...||.:|||..:||.:.|||...:.:.|     ..|...:.|.:|  :
Mouse   879 --AITAVSSNFSETNIIVVVATSEVGRYIAKDFLMDNWVAVTERYGMDWLDALVPVLGRTVS--T 939

  Fly   874 EQVITLSDFNEFKDFVNNSRQSLKGLEQAIQQTLEIMLT-NVQWKERNYHQMSRSIQQL 931
            :|.:|  :...|...|....|.:     .:|..|:.|.| |:|.|:|    ::|.::.|
Mouse   940 DQQVT--ELQHFFSTVLEEHQRV-----VVQAKLQAMKTKNLQNKKR----IARVVEWL 987

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	160/487 (33%)
		ERAP1_C	582..910	CDD:463368	97/350 (28%)
Lvrn	NP_083284.1	M1_APN-Q_like	102..570	CDD:341064	160/488 (33%)
		ERAP1_C	645..964	CDD:463368	95/345 (28%)