Protein Alignment SP1029 and Aopep

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_001276853.1
• Gene: Aopep / 72061
• MGIID: 1919311
• Length: 823
• Species: Mus musculus
• Alignment Length: 625
• Identity: 119/625 - (19%)
• Similarity: 218/625 - (34%)
• Gaps: 186/625 - (29%)

  Fly   139 ADLNRQLEGYYRSSYKDPVANLTKWIS--------VTQFEPASARLAFPCFDEPDFKAPFVVTLG 195
            ||..|.:..:|::.   |......|.:        .|...|.:.|..|||.:.|...:.:..|:.
Mouse   238 ADFPRAIRIWYKTK---PEGQSVAWTTDQNGRPCVYTMGSPINNRALFPCQEPPVAMSTWQATVR 299

  Fly   196 YHKKYTAISNMPEKETKPHETLADYIWCEFQESVPMSTYLVAYSVNDFSH-KPSTLPNSALFRTW 259
            ....:..:.: .|...||......|:...:..::||.....|.:|..::. ||...|...|....
Mouse   300 AAASFVVLMS-GENSAKPTPLREGYMSWHYYVTMPMPASTFAIAVGCWTEMKPKASPPDDLMTEH 363

  Fly   260 ARPNAIDQCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYR------- 317
            :.|.:..:.|         |:|......:::|.         .|.:.:..:..::.||
Mouse   364 SLPLSPSEAD---------LRYDNTCNHMEYPC---------RFQSASAASQDIIPYRVFAPVCL 410

  Fly   318 ----EIALLY------SAAHSSL------------------------------------ADKQRV 336
                :.|||:      |||||.|                                    ......
Mouse   411 EGACQEALLWLIPSCLSAAHSVLGTHPFSRLDILIVPTNFPSLGMASPHIIFLSQSTLTGTSHLC 475

  Fly   337 ASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASL---GVENINPEWRSMEQESLSNLLTIF 398
            .:.:.||:||.|||..:..:.||:.||:|||||::..:   ..:.:.|. .::||:.|...|...
Mouse   476 GTRLCHEIAHSWFGLAIGARDWTEEWLSEGFATHLEDIFWAEAQQLPPH-EALEQQELRACLRWH 539

  Fly   399 R-RDALESS---HPISRP-IQMVSEISES--------------FDQISYQKGSTVLRMMHLFLGE 444
            | :|.|.:|   ..:.|| .:....:|.|              |.|:.|.||..:||.:...|||
Mouse   540 RLQDELRNSPEGMQVLRPNKEETGHVSASGASVVKHGLNPEKGFMQVHYLKGYFLLRFLTRTLGE 604

  Fly   445 ESFRSGLQAYLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRD 509
            :.:...|:.::..|..:.....:..:.|.:...:.:.|..|  :::|:..|...:|.|
Mouse   605 KIYFPFLRKFVHLFHGQLILSQDFLQMLLENIPENKRLGLS--VENIVRDWLECSGIP------- 660

  Fly   510 YAARTAKLNQERYL-----------LNTQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECG 563
                 ..|.:||..           :.::||:       |:.:           |..|:. .:.|
Mouse   661 -----KALQEERKAEDCSPSRLARQVGSEVAK-------WIRV-----------NRRPRK-RKRG 701

  Fly   564 KNGESLPKTIQDLPGPDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDD 628
            |...:..|.     .|||.|:.              ..|.|..:||:.   :.:|.:.:...:.
Mouse   702 KREVAFEKL-----SPDQIVLL--------------LEWLLEQKTLSP---QTLHCLQQTYHLP- 743

  Fly   629 ALYLAWTGEQDYEIAMRLIEYLQREREYLPWKSAFENLKR 668
                    |||.|:..|..|.:.:.:    :..|:..::|
Mouse   744 --------EQDAEVRHRWCELVIKHK----YTKAYNQVER 771

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	89/441 (20%)
		ERAP1_C	582..910	CDD:463368	14/87 (16%)
Aopep	NP_001276853.1	GluZincin	<244..641	CDD:472708	82/419 (20%)
		Nucleolar localization signal. /evidence=ECO:0000269|PubMed:17803194	693..703		2/10 (20%)
		Leuk-A4-hydro_C	710..822	CDD:462686	17/97 (18%)