Protein Alignment SP1029 and Rnpepl1

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_001258106.1
• Gene: Rnpepl1 / 684035
• RGDID: 1595210
• Length: 724
• Species: Rattus norvegicus
• Alignment Length: 736
• Identity: 164/736 - (22%)
• Similarity: 261/736 - (35%)
• Gaps: 215/736 - (29%)

  Fly    41 QKYHLRILTL-LE-NPEDLRFSGSVKILIEALENTKN---------VTLHSKNL----TIDESQI 90
            |.:.||.|.| || .||....:|.:.:.:.||.....         :.|||.:.    ...||..
  Rat    37 QLFRLRHLQLGLELRPEARELAGCLVLELCALRPAPRALVLDAHPALRLHSVSFRRASATSESPC 101

  Fly    91 TLR-QIGGEG------------KKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAADLN 142
            |.. ...|.|            :...|..:..::|..|:           |::..:.:|.....:
  Rat   102 TFAFPAPGSGPPLPAFADAPGAESAGCPLAFRLDPFTDY-----------GSSLTITLPPEVQAH 155

  Fly   143 RQLEGYYRSSYKDPVA------NLT----KWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYH 197
            :..:...|.:..|..|      .||    |....||......|..|||||.|..|.
  Rat   156 QPFQVIVRYTSTDAPAIWWLDPELTYGNAKPFVFTQGHSVCNRSFFPCFDTPAVKC--------- 211

  Fly   198 KKYTAISNMPE-KETKPHETLADYIWCE----FQESVPMSTYLVAYSVNDFSHKPSTL-PNSALF 256
             .|:|:...|. .:.....|.:.|:..|    |....|:..||||....|.  ||:.: |.|
  Rat   212 -TYSAVVKAPSGVQVLMSATQSAYVEEEGLYHFHMEHPVPAYLVALVAGDL--KPADIGPRS--- 270

  Fly   257 RTWARP-----------NAIDQCDYAAQ--FGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAM 308
            |.||.|           .|::|...||:  :||.:...|:..|     ||       |.|...||
  Rat   271 RVWAEPCLLPTATSKLSGAVEQWLSAAERLYGPYMWGRYDIVF-----LP-------PSFPIVAM 323

  Fly   309 ENWGLVTYREIALLYSAAHSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYV-A 372
            || ..:|:...::|.|       |:..|..|: ||:||.||||.||...|.::||:||.|||. .
  Rat   324 EN-PCLTFIISSILES-------DEFLVIDVI-HEVAHSWFGNAVTNATWEEMWLSEGLATYAQR 379

  Fly   373 SLGVENINPEWRSMEQESLSNLLTIFRRDALE-------SSHPISRPIQMVSE----ISESFDQI 426
            .:..|.....:..:|        |.||.|||.       ...|:|: :|:..|    .|...:..
  Rat   380 RITTETYGAAFTCLE--------TAFRLDALHRQMRLLGEDSPVSK-LQVKLEPGVNPSHLMNLF 435

  Fly   427 SYQKGSTVLRMMHLFLGE-ESFRSGLQAYLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKS 490
            :|:||...:..:....|: :.|...|:||::|:.:.:....:|.:|......:.:.  :|.|.:
  Rat   436 TYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFTSVVAQDLLDSFLSFFPELKE--QSVDCR- 497

  Fly   491 IMDSWTLQTGYPVINVTRDYAARTAKLNQERYLLNTQVARAYRGGCWWVPLSYTTQAVQDFNNTA 555
                                    |.|..||:|                            |.|.
  Rat   498 ------------------------AGLEFERWL----------------------------NATG 510

  Fly   556 PKAWMECGKNGESLPKTIQDLPGPDQWVIFNTQLSTLYKVNYDAQNWK-----LLIETLTNGD-- 613
            |.........|.||.:.::.|  ...|.....:.:.......|...|:     |.::.|.:|.
  Rat   511 PPLAEPDLSQGSSLTRPVEAL--FQLWTAEPLEQAAASASAIDISKWRTFQTALFLDRLLDGSPL 573

  Fly   614 -FERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQREREYLPWKSAFENLKRVGRIVRQTP 677
             .|.:..:::.       |.:.....:.||.:|.::.:.| .:|.|      :|.||.|
  Rat   574 PQEVVMSLSKC-------YSSLLDSMNTEIRIRWLQIVVR-NDYYP------DLHRVRR------ 618

  Fly   678 DFEFFKRYMKKL-ILPIYEHL 697
               |.:..|.:: .:|:||.|
  Rat   619 ---FLENQMSRMYTIPLYEDL 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	127/524 (24%)
		ERAP1_C	582..910	CDD:463368	24/125 (19%)
Rnpepl1	NP_001258106.1	M1_LTA4H	30..507	CDD:341062	133/580 (23%)
		Leuk-A4-hydro_C	555..668	CDD:462686	22/105 (21%)