Protein Alignment SP1029 and Enpep

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_071587.2
• Gene: Enpep / 64017
• RGDID: 621228
• Length: 945
• Species: Rattus norvegicus
• Alignment Length: 939
• Identity: 314/939 - (33%)
• Similarity: 500/939 - (53%)
• Gaps: 104/939 - (11%)

  Fly    19 DSSADSIETTYNYYRLPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKNVTLHSKNL 83
            ||..:|.|  :..:|||..::|..|.|.:..|:|  || |::|.|.|.:...::|:::.||
  Rat    72 DSDDESGE--WKNFRLPDFIQPVHYDLEVKVLME--ED-RYTGIVSISVNLSKDTRDLWLH---- 127

  Fly    84 TIDESQIT----LRQIGGEG---------KKENCVSSTAVNPSHDFYILNTCQELLAG----NTY 131
             |.|::||    ||:..||.         ||:.             |::...:|.||.    :.|
  Rat   128 -IRETRITKLPELRRPSGEQVPIRRCFEYKKQE-------------YVVIQAEEDLAATSGDSVY 178

  Fly   132 ELYMPFAADLNRQLEGYYRSSYKDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGY 196
            .|.:.|...||..|.|:||::|.:.  ..||.|:.|..||..||.:|||||||:.||.:.::|.:
  Rat   179 RLTIEFEGWLNGSLVGFYRTTYTED--GQTKSIAATDHEPTDARKSFPCFDEPNKKATYNISLIH 241

  Fly   197 HKKYTAISNMP-EKETKPHETLADYIW--CEFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRT 258
            .|:|:|:|||| |||    ||| |..|  ..|.:|||||||||.::|:.|:....|..:......
  Rat   242 PKEYSALSNMPVEKE----ETL-DNDWKKTTFMKSVPMSTYLVCFAVHQFTSIQRTSRSGKPLTV 301

  Fly   259 WARPNAIDQCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLY 323
            :.:||.....:|||.....|..::|.:|.:::.|||:|:||:|||..|||||||||||||..|||
  Rat   302 YVQPNQKQTAEYAANITKAVFDFFEDYFAMEYSLPKLDKIAIPDFGTGAMENWGLVTYRETNLLY 366

  Fly   324 SAAHSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQ 388
            ....|:.:::|||||||||||.||||||:|||.||.|||||||||::...|||.:...:|:.:.|
  Rat   367 DPLLSASSNQQRVASVVAHELVHQWFGNIVTMDWWDDLWLNEGFASFFEFLGVNHAEADWQMLSQ 431

  Fly   389 ESLSNLLTIFRRDALESSHPISRPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQA 453
            ..|.::|.:...|:|.||||:...:...:||:..||.|||.||:::|||:..::..|.|:.|.|.
  Rat   432 VLLEDVLPVQEDDSLMSSHPVVVTVSTPAEITSVFDGISYSKGASILRMLQDWITPEKFQKGCQI 496

  Fly   454 YLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKLN 518
            ||:.|.:|||:..:.|:||.:|:::        .:|.:||:||.|.||||:.|       :.|.|
  Rat   497 YLENFKFKNAKTSDFWDSLEKASNQ--------PVKEVMDTWTSQMGYPVVTV-------SGKQN 546

  Fly   519 --QERYLLN-----TQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDL 576
              |:|:||:     :|...|. |..|.:|:.:|     :..|:....:....:.|.:|...:..
  Rat   547 VTQKRFLLDYKADPSQPPSAL-GYTWNIPIKWT-----ENGNSNITVYYRSNREGITLNANLSG- 604

  Fly   577 PGPDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTGEQDYE 641
               |.::..|......|:|||:|:.|..:.|||::... .....:|:..||||..||.....|||
  Rat   605 ---DGFLKINPDHIGFYRVNYEAETWDWIAETLSSNHM-NFSSADRSSFIDDAFALARAQLLDYE 665

  Fly   642 IAMRLIEYLQREREYLPWKSAFENLKRVGRIVRQTPD----FEFFKRYMKKLILPIYEHLNGIND 702
            .|:.|..||..|:::|||:..   :..|..|:....|    :...:.|.:..:.||.:.| |..|
  Rat   666 KALNLTRYLTSEKDFLPWERV---ISAVSYIISMFEDDRELYPLIETYFRSQVKPIADSL-GWQD 726

  Fly   703 TFSAIPQQDQVLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVYCTSI 767
            |.|.|.:    ||:..|:.:||:...|:.:..|...:..| .:.|    ..:|:|:|..||...:
  Rat   727 TGSHITK----LLRASVLGFACKMGAGEALGNASQLFEAW-LKGN----ESIPVNLRLLVYRYGM 782

  Fly   768 KH-GSDSDWEFLWTRYKKSNVAAEKRTILTALGCSREVWLLQRYLELTFDPKEAIRKQDSMWAFQ 831
            :: |:::.|.:...:|:|:::|.||..:|..|...::|.||.||||:..|| ..|:.||.....:
  Rat   783 QNSGNEAAWNYTLEQYQKTSLAQEKEKLLYGLASVKDVTLLARYLEMLKDP-NIIKTQDVFTVIR 846

  Fly   832 AVAFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQSL 896
            .:::|..|..:|..:...|.|::...:....:.:.|::: ::|...|.....:.:.|......:.
  Rat   847 YISYNSYGKSMAWNWIQLNWDYLVNRFTINDRYLGRIVT-IAEPFNTELQLWQMQSFFAKYPNAG 910

  Fly   897 KGLEQAIQQTLEIMLTNVQWKERNYHQMS 925
            .|.:.. :|.||.:..|::|.:.|...:|
  Rat   911 AGAKPR-EQVLETVKNNIEWLKLNRKSIS 938

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	191/474 (40%)
		ERAP1_C	582..910	CDD:463368	88/332 (27%)
Enpep	NP_071587.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..77		2/4 (50%)
		M1_APN-Q_like	92..531	CDD:341064	190/474 (40%)
		ERAP1_C	607..925	CDD:463368	88/334 (26%)