Protein Alignment SP1029 and erap1a

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_692516.3
• Gene: erap1a / 564068
• ZFINID: ZDB-GENE-091113-7
• Length: 933
• Species: Danio rerio
• Alignment Length: 978
• Identity: 315/978 - (32%)
• Similarity: 476/978 - (48%)
• Gaps: 122/978 - (12%)

  Fly     2 KWFLLFVAAL------GLGLATADSSADSIETTYNYYRLPTSLRPQKYHLRILTLLENPEDLRFS 60
            |:|...:.||      |....|.:.:...:...::..|||..::||.|.|.|   ..|...|.|:
Zfish     6 KYFHFTLVALFCALFAGNHAMTVNKNKTVLPFPWDKMRLPEIVKPQHYDLLI---HPNLTSLTFT 67

  Fly    61 GSVKILIEALENTKNVTLHSKNLTIDESQITLRQIGGEGKKENCVSSTAVNPSHDFYILN-TCQE 124
            |.|:|.||..::|:.:.||||||.:.::.:.       |.:::       :...|..|.. ...|
Zfish    68 GEVQIQIEVKQDTRAIILHSKNLQVSKALLL-------GSRQH-------HHHQDLQISEFEANE 118

  Fly   125 LLA----GNTYE-----LYMPFAADLNRQLEGYYRSSYKDPVANLTKWISVTQFEPASARLAFPC 180
            .:|    |.|:|     :::.|.|:|:....|:|:..|......: :.::.|||||..||.||||
Zfish   119 QIALFSEGFTFEKGSHVVHLEFYANLSDSFHGFYKGQYTTNSGEV-RMLASTQFEPTHARAAFPC 182

  Fly   181 FDEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHETLADYIW-CEFQESVPMSTYLVAYSVNDFS 244
            ||||.|||.|.:.:....::.:|||||:..|   ..|||.|. .:|...|.|||||||:.:.||.
Zfish   183 FDEPAFKANFTIRVRRESRHISISNMPKLRT---VELADGILEDQFDTMVKMSTYLVAFIICDFH 244

  Fly   245 HKPSTLPNSALFRTWARPNAIDQCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAME 309
            .......:......:..|..|.|.:||......:|.:|:::|.|.:||||.|..|:|||.:||||
Zfish   245 SISKKSQHGVEISVYTVPEKISQAEYALDTAVTMLDFYDEYFDIPYPLPKHDLAAIPDFQSGAME 309

  Fly   310 NWGLVTYREIALLYSAAHSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASL 374
            ||||.||||..||:....||.:||..:..|:|||||||||||||||:||.|||||||||.::..:
Zfish   310 NWGLSTYRESGLLFDPEKSSSSDKLGITKVIAHELAHQWFGNLVTMQWWNDLWLNEGFAKFMEYV 374

  Fly   375 GVENINPEWRSMEQESLSNLLTIFRRDALESSHPISRPIQMVSEISESFDQISYQKGSTVLRMMH 439
            .|...:||.: :....|....|....|:|.||||:|.|::..:||||.||.:||:||:.:|.|:.
Zfish   375 SVNITHPELQ-VNDYFLEKCFTALSVDSLSSSHPVSTPVENPAEISEMFDDVSYRKGACILNMLR 438

  Fly   440 LFLGEESFRSGLQAYLQKFSYKNAEQDNLWESLTQ-------------------------AAHKY 479
            .||..|.|:.|:..||:|.||:|....:||||||.                         .|.|:
Zfish   439 DFLTPEVFKYGIINYLKKHSYQNTVNSHLWESLTNICTSDGLDSGRLKLDGFCSKHTAETPASKW 503

  Fly   480 RSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKLNQERYLLNTQVARAYRGGCWWVPLSYT 544
            .. ..|.|:.:|||:||||.|:|:|.|  :...:...|.|||:|...:.:.: ....|.|||:|.
Zfish   504 FK-EDSVDVGAIMDTWTLQEGFPLITV--EVKGQEVTLKQERFLKGAESSNS-SSFLWQVPLTYI 564

  Fly   545 T---QAVQDFNNTAPKAWMECGKNGESLPKTIQD---LPGPDQWVIFNTQLSTLYKVNYDAQNWK 603
            |   .|||.|                 |.||.:|   ||...:|:.||..|...|.|:|::..|.
Zfish   565 TSGSNAVQRF-----------------LLKTERDVFYLPEKVEWIKFNVDLRGYYIVHYESGGWD 612

  Fly   604 LLIETLTNGDFERIHVI----NRAQLIDDALYLAWTGEQDYEIAMRLIEYLQREREYLPWKSAFE 664
            .||:.|...     |.:    :||.||.|...|....:...:.|:.|..||.:|.|.:|....|.
Zfish   613 CLIKQLRMN-----HTVFSSNDRASLIHDIFQLVSIEKVPLDKALNLSLYLSKESEIMPVTQGFS 672

  Fly   665 NLKRVGRIVRQTPDFEF---FKRYMKKLILPIYEHLNGINDTFSAIPQQDQVLLKTMVVNWACQY 726
            .|..:.:::.:....|.   .|.::.||..|:.:     ..::|......:.:|:..::.:||..
Zfish   673 ELVPLYKLMEKRDMQELENQLKSHLVKLFQPLID-----RQSWSDNGSVSERMLRNYLLLFACVR 732

  Fly   727 QVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVYCTSIKHGSDSDWEFLWTRYKKSNVAAEK 791
            :...||..|...:..|:   ..|.|..:|.:|...||....:  :|..|:||..:||:|...:||
Zfish   733 RYPSCVSTATQLFHKWK---ESDGKMWLPTDVSLVVYTEGAR--TDDGWDFLLEKYKRSVSPSEK 792

  Fly   792 RTILTALGCS----REVWLLQRYLELTFDPKEAIRKQDSMWAFQAVAFNEVGFLLAKKYFMDNVD 852
            ..|..||..|    :..|||:|..|     .|.::.||......:|:.|..||.||..:...|..
Zfish   793 WMIKAALSYSPLAHKLQWLLERSSE-----GEIMKTQDLPSMLISVSKNPKGFKLAWDFLKSNWG 852

  Fly   853 FIYKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQSLKGLEQAIQQTLEIMLTNVQWK 917
            .:.|.:...:..:||::..:::|..|....:|.:.|..:..|......::|||.||.:..|:.|.
Zfish   853 KLVKKFDLGSSAISRVVVGVTDQYSTKEMLDEVELFFGSLAQDQGSGLRSIQQALEKIQQNILWM 917

  Fly   918 ERN 920
            :||
Zfish   918 DRN 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	185/490 (38%)
		ERAP1_C	582..910	CDD:463368	87/338 (26%)
erap1a	XP_692516.3	M1_APN-Q_like	52..520	CDD:341064	185/490 (38%)
		ERAP1_C	591..911	CDD:463368	87/339 (26%)