Protein Alignment SP1029 and Lvrn

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_038953135.1
• Gene: Lvrn / 502160
• RGDID: 1562779
• Length: 987
• Species: Rattus norvegicus
• Alignment Length: 948
• Identity: 288/948 - (30%)
• Similarity: 447/948 - (47%)
• Gaps: 107/948 - (11%)

  Fly    29 YNYYRLPTSLRPQKYHLRILTLLENPED-----LRFSGSVKILIEALENTKNVTLHSKNLTIDES 88
            :::.|||..|.|..|.|.:...|: |::     |.|:|.|.|.:.....|..:.|||..|...:.
  Rat    90 WDHLRLPPWLVPLHYDLELWPRLQ-PDNLSTPSLTFTGRVNITVRCTVATSTLLLHSFFLNYKQV 153

  Fly    89 QI-------TLRQIGGEGKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAAD-LNRQL 145
            ::       |.....|....||...:..:    .:.:|:..|.|..|::|||...|:.. |....
  Rat   154 EVWGPLAPDTRNATVGRVPLENVWFALDM----QYVVLDLGQSLDPGSSYELNFDFSGQVLQEGS 214

  Fly   146 EGYYRSSYKDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKE 210
            ||.:.:.|.|  .:..:.:..||.||..||..|||||||..||.|.:|:.:|..|.|:||||:..
  Rat   215 EGLFLNLYTD--EDQLRALIATQMEPTFARHVFPCFDEPALKATFNITIIHHPGYVALSNMPQLG 277

  Fly   211 TKPHETLADYIW--CEFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRTWARPNAI--DQCDYA 271
            ......:....|  ..|..:..|.|||||..:.||.:...|.....: |.|||.:.|  ...|:|
  Rat   278 QSHRIDVNGSRWTVTSFHTTPRMPTYLVALVICDFDYVSRTERGKEI-RVWARKDDIADGYLDFA 341

  Fly   272 AQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQ-R 335
            |.....|..:.|..|.|.:||||.|.||:|.|..||||||||:.:....||  .....|.:|: .
  Rat   342 ANHTGPVFSFLEDLFNISYPLPKTDIIALPTFVNGAMENWGLMIFDASLLL--ELDDDLPEKRAM 404

  Fly   336 VASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFRR 400
            :.|:::||:.||||||||||.||.::|||||||:|. .:|:.|.   :......::...||:. .
  Rat   405 ILSILSHEVGHQWFGNLVTMSWWNNIWLNEGFASYF-EVGLTNY---FYPKVPRNMIFFLTVL-H 464

  Fly   401 DALESSH-----PISRPIQMVS---EISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQK 457
            |.||..|     .:|.|::..:   ||:..||..:|:||:.:..|:..||.:..|.:.|::||:.
  Rat   465 DILEDDHSLESRAVSTPVENFTETREINRLFDIYTYKKGACMAWMLAGFLSQHLFINALKSYLET 529

  Fly   458 FSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKLNQER- 521
            |||.|||||:||..:..|..:...:.....:|.||||||.|:|:|||.:.    |.|..:.||.
  Rat   530 FSYSNAEQDDLWRHIQMAIDEQSIIHLPATVKRIMDSWTHQSGFPVITLN----ASTGVVKQEPF 590

  Fly   522 YLLNTQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDLPG------PD 580
            ||...:.........|.||:.:....:     |.|..|::         |:....||      ..
  Rat   591 YLERVENQTLLSHNTWIVPIFWMKNGI-----TQPLVWLD---------KSSMIFPGMKLSDSDS 641

  Fly   581 QWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMR 645
            .|||.|..::..|:||||...||.|.:.|.. |.:.|.||||.||:.||..|:.....:.|.|:.
  Rat   642 DWVILNFNVTGYYRVNYDKLGWKKLNQQLEK-DPKAIPVINRLQLVSDAFALSKNNYIEIETALD 705

  Fly   646 LIEYLQREREYLPWKSAFENL--KRVGRIVRQTPDFEFFKRYMKKLILPIYEHLNGINDTFSAIP 708
            |.:|:.:|.|.|.|.....||  :.|...|:....:...|:|..|       .||.|...:|||.
  Rat   706 LTKYIAKEDEILVWFEVLVNLINREVVYDVKNYYLYPLLKKYFLK-------RLNSIWTIYSAII 763

  Fly   709 QQDQVLLKTMVVN---------WACQYQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVYC 764
            :::...|:...::         .||...:.||:..:...:|.|.  |:|:  ..:|..:...|.|
  Rat   764 RENMASLQDNFLSLLPLKKFFETACWLGLEDCLQLSRELFRKWM--AHPE--TAIPPQIEKVVLC 824

  Fly   765 TSIKHGSDSDWEFLWTRY-KKSNVAAEKRTILTALGCSREVWLLQRYLE--LTFDPKEAIRKQDS 826
            .:|..||:.||:||:..| .|:....:...::.|:|||::...|.|::|  :|..|.    :.:.
  Rat   825 NAIALGSNKDWDFLFNLYINKTEEQEDLFHLVHAMGCSKDPRTLNRFMEYDITVFPS----RFNE 885

  Fly   827 MWAFQAVAFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNN 891
            ....:.||.:|||..:||.:.::|...:|:.|.|  :.::.|:|.|...|.|.....|.:.|::.
  Rat   886 TNLIEVVAESEVGRYVAKDFLINNWVAVYERYGP--QSLNTLVSILGRTVSTDQQVMELQQFLST 948

  Fly   892 SRQSLKGL--EQAIQQTLEIMLTN-------VQWKERN 920
            ..:..:.:  ...:|:.....|.|       |:|..:|
  Rat   949 VLEEHQRIVAHAKLQEMKAENLKNKKRIARVVEWLRKN 986

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	163/480 (34%)
		ERAP1_C	582..910	CDD:463368	94/343 (27%)
Lvrn	XP_038953135.1	M1_APN-Q_like	102..569	CDD:341064	163/481 (34%)
		ERAP1_C	643..948	CDD:463368	93/322 (29%)