Protein Alignment SP1029 and CG4467

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Alignment Length: 1039
• Identity: 243/1039 - (23%)
• Similarity: 412/1039 - (39%)
• Gaps: 201/1039 - (19%)

  Fly    34 LPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKNVTLHSKNLTIDESQITLRQIGGE 98
            ||||:||.:|   ::|:..|...|...|.|.|.:...:.|..:.||.::|.:.|..|...  |.:
  Fly   138 LPTSVRPLRY---MVTIHPNLTTLDVKGQVTIDLHVEKETNFIVLHIQDLNVTEKAIVTP--GPK 197

  Fly    99 GKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAADLNRQLEGYYRSSYKDPVANLTKW 163
            |.....|......|....|| ...:.|...:.|.|.:.:.:.||.:.||:|...|:.. ..:.:.
  Fly   198 GYALKIVKVLEFPPRQQLYI-EVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQYESS-NGVERL 260

  Fly   164 ISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHETLADYIWC----- 223
            ::.|.|.|..||.||||||||..:|||.:::...:.:..:||.....|   |.:..|:..
  Fly   261 LAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTT---EDVGFYMGTGLLRD 322

  Fly   224 EFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRTWARP-------------------------- 262
            :|.|:.|:....||:.|:|| .:.|..|::|...|...|
  Fly   323 DFIETPPLPADAVAWVVSDF-QRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKNPPV 386

  Fly   263 ----------------------------------------------------NAIDQCDYAAQFG 275
                                                                ::|.:......:.
  Fly   387 RNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRAPSYTFYA 451

  Fly   276 PK---------------VLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSA 325
            |:               ||:|.:.:..|.:||.|:|.:|:|......:.:.||||.:...|   .
  Fly   452 PRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLKTSFL---T 513

  Fly   326 AHSSLADKQRVASV--VAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINP---EWRS 385
            ..||:..:|...|.  :|..:..|:||.:.:.|...|:||.||...|   ||:..:.|   .|..
  Fly   514 DPSSITSEQYQFSALRIAEAMVRQFFGGITSRKVLKDVWLWEGLIQY---LGIHALAPLQETWPL 575

  Fly   386 MEQESLSNLLTIFRRDALESSHPISRPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSG 450
            .|...|.........||::....|...........|.|    .||.:.:..|:|..:||:.||..
  Fly   576 REMYLLKMATAALDIDAIQGWDSIMNGTSHDGNNEEFF----VQKTAAIFSMLHTAIGEDRFRGC 636

  Fly   451 LQAYLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTR------- 508
            |.::|:...::.||..:||...|:.|:      .|.:||.:|..||.|.|:|::.||:
  Fly   637 LGSFLKVNRFRTAEPTDLWTICTKKAN------GSKNIKDMMTLWTHQPGFPLLTVTKMGNSISI 695

  Fly   509 -DYAARTAKL-----------NQERYLLN-----TQVARAYRGG--------CWWVPLSYTTQAV 548
             ....|.|:.           |..:..||     :.||...:|.        .|..|::|.|
  Fly   696 SQRPFRPAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKWIFPVTYVT--- 757

  Fly   549 QDFNNTAPKAWMECGKNGESLPKTIQDLPGPDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGD 613
             |.||.:...||:......::|:.:       :|:..|...:..|:|.|:..||..|||.|. .:
  Fly   758 -DINNVSETLWMQNVDVTFNVPENV-------KWIKVNAIQNGYYRVVYNDDNWASLIEELA-AN 813

  Fly   614 FERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQREREYLPWKSAFENLKRVGRIVRQTPD 678
            ..|....:|..::.||..|........||.|.:|:||..|..|.|...|..:|::..||::.:..
  Fly   814 PNRFTSEDRLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMALALRHLEKWRRILKYSEC 878

  Fly   679 FEFFKRYMKKLILPIYEHLNGINDTFSAIPQQDQVLLKTMVVNWACQYQVGDCVPQA---LAYYR 740
            |.....::|..|..:.|.:...:|...|..     ||:..|:..:..::..|.:.:|   |..|.
  Fly   879 FLMLSEFIKMKISTVMEKVGWSDDGDVATR-----LLRPEVLLASVLWEDIDSITKAKNMLNQYL 938

  Fly   741 NWRAEANPDEKNPVPINVRSTVYCTSIKHGSDSDWEFLWTRY----KKSNVAAEKRTILTALGCS 801
            .:...|       :|.|:|..||..||..|....|:..|.|:    :.|....|:..:|.|||.:
  Fly   939 YYNGTA-------IPPNLREVVYTGSILSGEYIYWQHCWERFVNLQRTSETFVERMQLLRALGRT 996

  Fly   802 REVWLLQRYL-ELTFDPKEAIRKQDSMWAFQAVAFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDM 865
            ::.||..|.| .:|..|.|.:     :...:|:|....|..:|.::.......:.|...|.|...
  Fly   997 KDAWLQNRLLSHVTMLPTEEV-----VQVLKAIAGTPTGGAMACRFLQAKWFELEKRLGPGTISF 1056

  Fly   866 SRLLSPLSEQVITLSDFNEFKDFVNNSRQSLKGLEQAIQQTLEIMLTNVQWKERNYHQMSRSIQ 929
            ::::|.:::...|..|::|.|..|:...:. .|: ..:..||..:.:||:|..|:...:.:.::
  Fly  1057 AKVISAITQYGATKFDYDELKSLVHRFGRG-HGM-SVLNMTLSSVASNVEWVARSQTSLYKWVE 1118

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	126/557 (23%)
		ERAP1_C	582..910	CDD:463368	83/335 (25%)
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	126/558 (23%)
		ERAP1_C	783..1078	CDD:463368	78/312 (25%)