Protein Alignment SP1029 and CG5849

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_650979.1
• Gene: CG5849 / 42556
• FlyBaseID: FBgn0038897
• Length: 968
• Species: Drosophila melanogaster
• Alignment Length: 945
• Identity: 257/945 - (27%)
• Similarity: 433/945 - (45%)
• Gaps: 129/945 - (13%)

  Fly     8 VAALGLGLATADSSADSIETTYNYYRLPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALEN 72
            |..:.|||..:.|..:...:    .|||.:..|..|.|.|.:.:...: |.|||:..|.:...::
  Fly     9 VVLVTLGLLVSGSMGERERS----LRLPNATYPLFYQLHISSDIHKGQ-LLFSGNATIDVAIRQS 68

  Fly    73 TKNVTLHSKNLTIDESQITLRQIGGEGKKENCVSSTAVNPSHDFYILNTCQELLA---GNTYELY 134
            |..:.||:||||  :.|||:.::..||.:.....:..::|:....|::..:...|   |..|.|.
  Fly    69 TNEIVLHAKNLT--DIQITVHRLMAEGSEIVDDLTHTLHPTAALLIIHPIENYQAFEEGQQYRLE 131

  Fly   135 MPFAADLNRQLEGYYRSSYKDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKK 199
            :.:.|.:..:..|.|...|:|...|.|.:::.||.||...||.|||:|||.||:.|.:.:.:...
  Fly   132 ILYTAIMASRPAGLYYMDYRDEENNHTVYVAATQCEPTYGRLIFPCYDEPGFKSNFSIKITHGSS 196

  Fly   200 YTAISNMPEKETKPHETLADYIWCEFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFR-----TW 259
            ::||||||.||...|   .|.....|..:.|:||||||:.::||.....|      :|     .:
  Fly   197 HSAISNMPVKEVLAH---GDLKTTSFHTTPPISTYLVAFVISDFGSISET------YRGITQSIY 252

  Fly   260 ARPNAIDQCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYS 324
            ..|.:.::...|.:...:.:...|.:||:.:||||:|.:|:......|||||||:||:::.||.:
  Fly   253 TSPTSKEKGQVALKNAVRTVAALEDYFGVSYPLPKLDHVALKKNYGAAMENWGLITYKDVNLLKN 317

  Fly   325 AAHSSLADKQRVASVVA-HELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQ 388
            .  ||...|:::..:.. ||:|||||||||:.:|||..|:|||||||.:.:..:.|.|..:.|:.
  Fly   318 I--SSDGQKRKLDLITQNHEIAHQWFGNLVSPEWWTYTWMNEGFATYFSYVITDLIYPNDKMMDM 380

  Fly   389 ESLSNLLTIFRRDALESSHPISRPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQA 453
            .......:.:..::....||:|..::...:|...||.|||::|:.|::|.|....::.|..|:..
  Fly   381 FMTHEADSAYSYNSFFDVHPMSHYVEGEKDIMGVFDIISYKRGACVIKMFHHAFRQKLFVRGISH 445

  Fly   454 YLQKFSYKNAEQDNLWESL---TQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTA 515
            :|:|:.|..|.:.||:::|   .|....:...|.:..|:.||.|||.....|::.|||:|...|.
  Fly   446 FLEKYRYSVANELNLFDALHSELQDDEYFSHQPWASRIREIMLSWTHSEWLPILVVTRNYENNTI 510

  Fly   516 KLNQERYLLNTQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPK-----TIQD 575
            ...|....:..::        ||:|:::.|....:|.:|....:|.        |:     :::|
  Fly   511 TFTQRSVHMKDEL--------WWIPINFATTQSPNFEDTQVDMFMP--------PQPQYTVSLED 559

  Fly   576 L----PGPDQWVIFNTQLSTLYKVNYDAQNWKLLIETL-TNGDFERIHVINRAQLIDDALYLAWT 635
            |    .|.| |::.|.|.:..|.|.||..|...:...| ||...  ||.|||..|..|...|...
  Fly   560 LNIHVSGRD-WIMVNKQHTGFYLVRYDTDNLMAIARQLQTNHSV--IHPINRLGLFRDLGPLIEH 621

  Fly   636 GE-QDYEIAMRLIEYLQREREYLPWKSAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHL-- 697
            .| :..|:...|::||:.|.:.|.|....:.::.:.|.:..|.....|..::::|:.|.:..:
  Fly   622 NEIEQVEVVFELLKYLELEEDVLTWNQLQDTIECLTRNLHGTSSQSLFNEFVRRLVGPTFRRVYV 686

  Fly   698 -NGIN----DTFSAIPQQDQVLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDE---KNPV 754
             .|:|    ..|..|            :..||...    :|:.|.|.|....|...|:   |:..
  Fly   687 EQGVNLAEDGMFRGI------------LEIACSAD----LPECLEYTRRLAKEHIIDKIYFKDGS 735

  Fly   755 PIN-VRSTVYCTSIKHGSDSDWEFLWTRYKK-SNVAAEKRTILTALGCSREVWLLQRYLELTFDP 817
            ..: :..:|.|..:::.||.|::.:....:: ...:.....|:.||.|::....|..||
  Fly   736 DYHAIIDSVLCMGVRYLSDQDFQRIIDMMQEIDRASVYYDDIIYALRCTQSHRHLLYYL------ 794

  Fly   818 KEAIRKQDSMWAFQAVAFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDMSRLLS-PLSEQVIT--- 878
             |.:..::|.....: .|.::.:||          :|||         |.|.| |:..|.|.
  Fly   795 -EGLMGENSTHMVLS-EFEDLMYLL----------YIYK---------SNLASRPVIWQYIERNY 838

  Fly   879 ---------LSDFNEFKDFV-NNSRQSLKGLEQAI 903
                     |..|.:...|| .:.|...:.|.|.|
  Fly   839 KVLCRAPNFLEHFKQLAGFVPRHQRSHFERLRQTI 873

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	149/466 (32%)
		ERAP1_C	582..910	CDD:463368	79/350 (23%)
CG5849	NP_650979.1	M1_APN-Q_like	38..492	CDD:341064	149/467 (32%)
		ERAP1_C	569..841	CDD:463368	71/316 (22%)