Protein Alignment SP1029 and lta4h

DIOPT Version :9

• Sequence 1: NP_001263065.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_998451.1
• Gene: lta4h / 406575
• ZFINID: ZDB-GENE-040426-2477
• Length: 611
• Species: Danio rerio
• Alignment Length: 629
• Identity: 136/629 - (21%)
• Similarity: 240/629 - (38%)
• Gaps: 166/629 - (26%)

  Fly    61 GSVKILIEALENTKNVTLHSKNLTIDESQITLRQIGGEGKKENCVSSTAVNPSHDFYILNTCQEL 125
            |.|.:.:|.||:      ...:||:|...:.:.::...|:    .:...:...|.|
Zfish    36 GKVALTVEVLED------KFSSLTLDSKDLKISKVSANGQ----AAKFELGAKHKF--------- 81

  Fly   126 LAGNTYELYMPFAADLNRQ----LEGYYRSSYKDPVANLTKWIS------------VTQFEPASA 174
             .|:..|:.:||  :|:|.    :|..|.:|   |.|...:|::            .:|.:....
Zfish    82 -KGSPLEITLPF--ELSRGQHVIVEIEYETS---PTATALQWLTPKQTAGKKHPYLFSQCQATHC 140

  Fly   175 RLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHETLADYIWCEFQESVPMSTYLVAYS 239
            |...||.|.|..|..:...:...::..|:.:......:|..:.:..:...|::.|||.:||:|..
Zfish   141 RTMVPCQDTPSVKHTYYAQVSVPRELVALMSALRDGQEPDPSDSSRVIYRFRQPVPMPSYLIAIV 205

  Fly   240 VNDFSHKPSTLPNSALFRTWARPNAIDQCDYAAQF--------------GPKVLQYYEQFFGIKF 290
            |.....: ...|.|   |.|:....:|:..|  :|              ||.|...|:...
Zfish   206 VGALESR-EIGPRS---RVWSEKEYVDEAAY--EFAETETMLKTAESLAGPYVWGQYDVLV---- 260

  Fly   291 PLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQRVASVVAHELAHQWFGNLVTM 355
             ||       |.|..|.|||         ..|.....:.||..:.:|.|:|||::|.|.|||||.
Zfish   261 -LP-------PSFPYGGMEN---------PCLTFVTPTVLAGDRSLAGVIAHEISHSWTGNLVTN 308

  Fly   356 KWWTDLWLNEGFATYVASLGVENINPE----------WR----SMEQESLSNLLTIFRRDALESS 406
            :.|...|||||...|:..:....:..|          |:    |::|...:|:||    :.:.:.
Zfish   309 RTWEHFWLNEGHTVYIERMIARCMEGEQLRQFKGIGGWKELHESVKQFGANNVLT----NLVPNL 369

  Fly   407 HPISRPIQMVSEISESFDQISYQKGSTVL-RMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNLWE 470
            |.:        :..|:|..:.|:||..:| .:..|..|.|.|...:::|:|.|:|.:...:. |:
Zfish   370 HEV--------DTDEAFSSVPYEKGFALLYHLEELMGGPEVFMGFVKSYIQLFAYGSVTTEE-WK 425

  Fly   471 SLTQAAHKYRSLPKSYDIKSIMD--SWTLQTGYPVINVTRDYAARTAKLNQERYLLNTQVARAYR 533
            :     :.:.......||.:.:|  :|....|...:....|                |.:|.|..
Zfish   426 N-----YLFTYFKDKVDILNKVDWNAWMHTPGMAPVRPQYD----------------TTMADACT 469

  Fly   534 GGCW-WVP------LSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDLPGPDQWVIFNTQLST 591
            ..|. ||.      .|:|...|:..|  :|:..       |.:...:|:.|.|...|   .::..
Zfish   470 SLCQKWVKAKEADLASFTEADVKQLN--SPQLI-------EFMALLLQEDPLPLSHV---KKMGE 522

  Fly   592 LYKVNYDAQNWKLLIETLTNGD--FERIHVINRAQLIDDALYLA 633
            :||:|           .:.|.:  |..:.:..:||. ::|:.||
Zfish   523 VYKLN-----------NIKNAEVRFRWLRICVKAQW-EEAVPLA 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_001263065.1	Peptidase_M1	33..431	CDD:279741	92/413 (22%)
		M1_APN_2	43..502	CDD:189008	109/487 (22%)
		ERAP1_C	583..908	CDD:288671	11/53 (21%)
lta4h	NP_998451.1	leuko_A4_hydro	18..607	CDD:274120	136/629 (22%)
		M1_LTA4H	18..449	CDD:189006	108/482 (22%)
		Leuk-A4-hydro_C	467..606	CDD:286244	24/112 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810