Protein Alignment SP1029 and erap1b

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_956500.2
• Gene: erap1b / 393175
• ZFINID: ZDB-GENE-040426-934
• Length: 963
• Species: Danio rerio
• Alignment Length: 968
• Identity: 309/968 - (31%)
• Similarity: 475/968 - (49%)
• Gaps: 142/968 - (14%)

  Fly    29 YNYYRLPTSLRPQKYHLRI---LTLLENPEDLRFSGSVKILIEALENTKNVTLHSKNLTIDESQI 90
            :|..|||.::.|..|:|.|   ||.|:      |:|||:|.||.|::||.:.||||||.|..:::
Zfish    42 WNKMRLPDTISPLHYNLLIHPNLTSLD------FTGSVQIQIEVLQDTKTIILHSKNLQISSARL 100

  Fly    91 TLRQIGGEG----------KKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAADLNRQL 145
            ....|..:.          ::...||..|:              |..|:.|.:.:.|||:|:...
Zfish   101 LDANIAQQQPLKVLEYPYFQQIALVSDKAL--------------LKRGHVYSVELHFAANLSESF 151

  Fly   146 EGYYRSSYKDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKE 210
            .|:|:|:|:....:: :.::.||||..|||.||||||||.|||.|.|.:....|:.|:||||:..
Zfish   152 HGFYKSTYRTSKGDV-RVVASTQFEATSARAAFPCFDEPAFKANFSVQIRREAKHIALSNMPKLR 215

  Fly   211 TKPHETLADYIWCEFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRTWARPNAIDQCDYAAQFG 275
            |.  |........:|..||.||||||||.|:||.....|..:......:|.|..|||.::|....
Zfish   216 TL--ELKNGLFEDQFDVSVKMSTYLVAYIVSDFLSISKTSQHGVQISVYAVPEKIDQAEFALDAA 278

  Fly   276 PKVLQYYEQFFGIKFPLPK--------------------IDQIAVPDFSAGAMENWGLVTYREIA 320
            .|:|.:|:.:|.|.:||||                    :|..|:|||.:||||||||.||||.|
Zfish   279 VKLLDFYDDYFDIPYPLPKQEKPTIKHAKEEFSVYIICFVDLAAIPDFQSGAMENWGLTTYRESA 343

  Fly   321 LLYSAAHSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRS 385
            ||:....||.:||..:..::|||||||||||||||:||.|||||||||.::..:.|...|||.:
Zfish   344 LLFDPHKSSASDKLGITMIIAHELAHQWFGNLVTMQWWNDLWLNEGFAKFMEFVSVNITNPELQ- 407

  Fly   386 MEQESLSNLLTIFRRDALESSHPISRPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSG 450
            :|...|.........|:|.||||:|.|::..::|.|.||.:||.||:.:|.|:..||..:.|:.|
Zfish   408 VEDYFLGKCFEAMEVDSLSSSHPVSTPVENPAQIQEMFDDVSYDKGACILNMLREFLTPKIFKLG 472

  Fly   451 LQAYLQKFSYKNAEQDNLWESLTQ-------------------------AAHKYRSLPKSYDIKS 490
            :..||:.:||:|....|||||||.                         .|.|:.| ....|:|:
Zfish   473 IVKYLKHYSYQNTVNSNLWESLTNVCDSDGLDEGRLKGDESCRHSASNTGASKWHS-EDELDVKA 536

  Fly   491 IMDSWTLQTGYPVINVTRDYAARTAKLNQERYLLNTQVARAYRGGCWWVPLSYTTQ---AVQDFN 552
            :|::||||.|:|:|.:.  ...|..:|:|||||.:..:::. ....|.|||:|.|.   .|..|
Zfish   537 MMETWTLQEGFPLITIA--VKGREVRLSQERYLKSDDLSQT-SSFLWQVPLTYITSDSTTVHRF- 597

  Fly   553 NTAPKAWMECGKNGESLPKTIQD---LPGPDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDF 614
                            |.||..|   ||....|:.||..:|..|.|:|:...|..|| ||...:.
Zfish   598 ----------------LLKTKTDVLYLPEEVDWIKFNVDMSGYYIVHYEGSGWDDLI-TLLKHNH 645

  Fly   615 ERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQREREYLPWKSAFENLKRVGRIVRQTPDF 679
            ..:...:||.||::|..|...|:...:.|:.|..||.:|.|.:|....|..|..:.:::.:. |.
Zfish   646 TALSSNDRASLINNAFQLVSVGKLPLDKALDLTLYLSKETEIMPVTQGFNELVPLYKLMEKR-DM 709

  Fly   680 EFFKRYMKKLILPIYEHLNGINDTFSAIPQQ--------DQVLLKTMVVNWACQYQVGDCVPQAL 736
            ...:..||..||.:::.|         |.||        .:.:|::.::.:.|......||..|.
Zfish   710 VELENQMKGYILQLFQKL---------IEQQLWTDEGSVSERMLRSYLLLFGCVRGHPPCVSNAT 765

  Fly   737 AYYRNWRAEANPDEKNPVPINVRSTVYCTSIKHGSDSDWEFLWTRYKKSNVAAEKRTILTALGCS 801
            ..:..||   :.|....:|.:|...|:  |:...::..|:||:.:||:|...:.|..|..||..|
Zfish   766 QLFNLWR---DSDGNMSLPNDVTMAVF--SVGARTEDGWDFLFEKYKESMYVSMKSRIKQALMTS 825

  Fly   802 ----REVWLLQRYLELTFDPKEAIRKQDSMWAFQAVAFNEVGFLLAKKYFMDNVDFIYKFYHPLT 862
                :..|::::.||     .|.|:.||..:...:|:.|...:..|..:...|.|.:.|.:...:
Zfish   826 PLDHKLKWMMEQSLE-----GELIKTQDLPYVVTSVSRNPKAYKHAWDFLQANWDSLIKKFDLGS 885

  Fly   863 KDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQSLKGLEQAIQQTLEIMLTNVQWKERN 920
            ..::.::..::.|..|.....|.::|.:..:.......:.|||.:|.:..|::|.::|
Zfish   886 HSIAHMVVGVTNQYSTREMLAEVRNFFSLLQPETGAELRCIQQAVENIEENIRWMDKN 943

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	193/512 (38%)
		ERAP1_C	582..910	CDD:463368	81/339 (24%)
erap1b	NP_956500.2	M1_APN-Q_like	54..543	CDD:341064	193/513 (38%)
		ERAP1_C	614..934	CDD:463368	81/340 (24%)