Protein Alignment SP1029 and anpepb.1

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_001082794.1
• Gene: anpepb.1 / 322533
• ZFINID: ZDB-GENE-030131-1253
• Length: 965
• Species: Danio rerio
• Alignment Length: 944
• Identity: 347/944 - (36%)
• Similarity: 521/944 - (55%)
• Gaps: 82/944 - (8%)

  Fly    14 GLATADSSADSIETT------YNYYRLPTSLRPQKYHLRILTLLE-NPEDLR-FSGSVKILIEAL 70
            |..|...:..:|.||      ::.:|||.:|.|:.|.:.:...|: |.|.|. |:|...::...:
Zfish    53 GPTTNVPATTNIPTTVPSNEPWDQWRLPQTLSPETYKVTLWPRLQKNAEGLYIFTGDSSVVFRCV 117

  Fly    71 ENTKNVTLHSKNLTIDESQITLRQIGGEGKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYM 135
            |||..:.:||..|||.:| .||:.:||.....  :.||.:.|...:..:...:||.||.:||||.
Zfish   118 ENTDLILIHSNKLTIKDS-TTLKALGGNPAPN--IVSTKMYPKTQYMAIWLDRELTAGESYELYT 179

  Fly   136 PFAADLNRQLEGYYRSSYKDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKY 200
            .|..:|:..|.|:|||.|.|. ..:.|.::.||.:...||.||||||||..||.|.:.|.:....
Zfish   180 EFVGELSDDLGGFYRSEYYDE-NGVLKVVATTQMQATDARKAFPCFDEPAMKAVFNIVLLHDPGT 243

  Fly   201 TAISNMPEKETKPHETLADYI---WCEFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRTWARP 262
            .|:||....|..|  ...|.|   ...|..:..|||||:|:.|::|::....|.:..: |.:||.
Zfish   244 VALSNGVVIEEIP--VTVDGISLTKTTFAPTEKMSTYLLAFIVSEFTYIEQKLDDLQI-RIFARK 305

  Fly   263 NAID--QCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSA 325
            .|||  |.:||.....|:|:::|:::...:||||.||||:|||:|||||||||:||||.||||..
Zfish   306 EAIDANQGEYALSVTGKILRFFEEYYNSSYPLPKSDQIALPDFNAGAMENWGLITYRETALLYDE 370

  Fly   326 AHSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQES 390
            ..||..:|:||.:|:||||||||||||||::||.|||||||||:||..||.:...|.|...:...
Zfish   371 EMSSNGNKERVVTVIAHELAHQWFGNLVTIRWWNDLWLNEGFASYVEYLGADEAEPLWNIKDLIV 435

  Fly   391 LSNLLTIFRRDALESSHPIS---RPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQ 452
            |:::..:|..|||.||||:|   ..:|...:|||.||.|||.||::||||:..||.|:.|..||:
Zfish   436 LNDVHRVFAIDALASSHPLSSKEEDVQRPEQISEVFDTISYSKGASVLRMLSNFLSEDVFTQGLR 500

  Fly   453 AYLQKFSYKNAEQDNLWESLTQAAHKY-RSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAK 516
            .||:.|.:.|....:||:.|..|..:. ..||:|  :|.|||.|.||.|:||:.:.    ..|.:
Zfish   501 TYLEHFKFNNTVYTDLWDHLQMAVDETGTELPRS--VKDIMDRWVLQMGFPVVTIN----TVTGQ 559

  Fly   517 LNQERYLLNTQVARA-----YRGGCWWVPLSYT-TQAVQDFNNTAPKAWMECGKNGESLPKTIQ- 574
            ::||.:||:.:....     |.   |:||:::| .:|::      |:.|:        |.|..|
Zfish   560 ISQEHFLLDPETKPEPSEFNYE---WFVPITWTKNEAIK------PQYWL--------LQKNTQF 607

  Fly   575 -DL-PGPDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTGE 637
             |: ...::||:.|......|:||||.|||:.|:..|.... |.|.|||||||||||..||..|.
Zfish   608 DDMKTNANEWVLANINTVGYYRVNYDEQNWERLLNALQTSR-ESIPVINRAQLIDDAFNLAKAGI 671

  Fly   638 QDYEIAMRLIEYLQREREYLPWKSAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHLNGIND 702
            ....:|:|..|:|..|.||:||:||..||.....:..::..:...:.|::|.:.|::|:...:.|
Zfish   672 IKTTLALRTTEFLDVETEYMPWQSALNNLDYFYLMFDRSEVYGHMQAYIRKQVTPLFEYFTELTD 736

  Fly   703 TFSAIP-----QQDQVLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTV 762
             :..:|     |.:||    ..:..||...:.:|.....:::..|   .|.::.||:..|:||||
Zfish   737 -WQGVPDNHTEQYNQV----NALRVACSIGLKNCTDLVTSWFGEW---MNNEDVNPIHANLRSTV 793

  Fly   763 YCTSIKHGSDSDWEFLWTRYKKSNVAAEKRTILTALGCSREVWLLQRYLELTFDPKEAIRKQDSM 827
            ||::|..|...:|||.|..::|::||:||..:..|:.|:.:.|||.||||.|.|..: |||||:.
Zfish   794 YCSAIAAGGAEEWEFAWKMFEKTSVASEKDKLRAAMACATQPWLLNRYLEYTLDANK-IRKQDAT 857

  Fly   828 WAFQAVAFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDMSRLLSPLSEQVIT------LSDFNEFK 886
            ....::|.|..|..||..:...|.::|:..|...:...|.|::.::::..|      |..|.|..
Zfish   858 STIVSIASNVGGQSLAWDFVRANWEYIFNQYGGGSFSFSNLINGVTKRFSTEFELKQLMQFKEDN 922

  Fly   887 DFVNNSRQSLKGLEQAIQQTLEIMLTNVQWKERN 920
            :.:.....||     ||||::|....|::|.|:|
Zfish   923 EHIGFGSGSL-----AIQQSIERTKANIKWVEQN 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	198/465 (43%)
		ERAP1_C	582..910	CDD:463368	113/338 (33%)
anpepb.1	NP_001082794.1	M1_APN-Q_like	88..544	CDD:341064	198/464 (43%)
		ERAP1_C	617..943	CDD:463368	113/340 (33%)