Protein Alignment SP1029 and ape2

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_595998.1
• Gene: ape2 / 2540648
• PomBaseID: SPBC1921.05
• Length: 882
• Species: Schizosaccharomyces pombe
• Alignment Length: 939
• Identity: 304/939 - (32%)
• Similarity: 470/939 - (50%)
• Gaps: 102/939 - (10%)

  Fly    24 SIETTYNYYRLPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKNVTLHSKNLTIDES 88
            |.|...|...||.:::|..|.   |:|..:.|...:.|.|.:.::.||::.::|||..||.|
pombe    10 SKEDDKNRNLLPKNVKPIHYD---LSLYPDLETFTYGGKVVVTLDVLEDSNSITLHGINLRI--- 68

  Fly    89 QITLRQIGGEGKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAADLNRQLEGYYRSSY 153
             :|.....|    ...|.::.|:...:..:|.....:.|.:...|.:||.|.::..:||:|||||
pombe    69 -LTAALEWG----SQTVWASEVSYGDERIVLQFPSTVPANSVAVLTLPFTARISSGMEGFYRSSY 128

  Fly   154 KDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHETLA 218
            .|...| ||:::.||.||.|||.||||:|||..||.|.:.:...:.||.:|||...|    ||:.
pombe   129 VDSDGN-TKYLATTQMEPTSARRAFPCWDEPALKATFTIDITAKENYTILSNMNAVE----ETVK 188

  Fly   219 DYI-WCEFQESVPMSTYLVAYSVNDF---------SHKPSTLPNSALFRTWARPNAIDQCDYAAQ 273
            |.: ...|.|:..|||||:|:.|.:.         .|.| .||    .|.:..|...:|..:||:
pombe   189 DGLKTARFAETCRMSTYLLAWIVAELEYVEYFTPGKHCP-RLP----VRVYTTPGFSEQGKFAAE 248

  Fly   274 FGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQRVAS 338
            .|.|.|.::...||..:||||.|.:|:|||.|||||||||||||..|:|.| ..|:....:|||.
pombe   249 LGAKTLDFFSGVFGEPYPLPKCDMVAIPDFEAGAMENWGLVTYRLAAILVS-EDSAATVIERVAE 312

  Fly   339 VVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFRRDAL 403
            ||.||||||||||||||::|..|||||||||:::.....:..|||:..|.....||.:....|||
pombe   313 VVQHELAHQWFGNLVTMQFWDGLWLNEGFATWMSWFSCNHFYPEWKVWESYVTDNLQSALSLDAL 377

  Fly   404 ESSHPISRPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNL 468
            .|||||..||....||::.||.|||.|||.|:||:..::||::|..|:|.|:.|..|.|...::|
pombe   378 RSSHPIEVPIMHDYEINQIFDAISYSKGSCVIRMVSKYVGEDTFIKGIQKYISKHRYGNTVTEDL 442

  Fly   469 WESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKLNQERYLLNTQVARAYR 533
            |.:|        |.....||.|.|.:||.:|||||::|:........ :.|.|:|....|.....
pombe   443 WAAL--------SAESGQDISSTMHNWTKKTGYPVLSVSETNDGELL-IEQHRFLSTGDVKPEED 498

  Fly   534 GGCWWVPLSYTT----QAVQDFNNTAPKAWMECGKNGESLPKTIQDLPGPDQWVIFNTQLSTLYK 594
            ...:|.||...|    :||.|     .||.:     .:...|...|....:.:.: |::.|.:|:
pombe   499 TVIYWAPLKLKTMKDGKAVVD-----EKAVL-----SDRSKKIKVDKEALESYKL-NSEQSGIYR 552

  Fly   595 VNYDAQNWKLLIE-TLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQREREYLP 658
            |||.|.:.|.|.: .:...|:  :.|.:||.||.|...|:..|.......:.||:..:.|..::.
pombe   553 VNYSADHLKKLSQIAVEKPDY--LSVEDRAGLIADVASLSRAGYGKVSSTLDLIKTWKDEPNFVV 615

  Fly   659 WKSAFENLKRVGRIVRQTPDFEF--FKRYMKKLILPI-YEHLNGINDTFSAIPQQDQVL--LKTM 718
            :.   |.|.|:..| :.|..||.  ....||||:|.: ....:.:...|.|  ..|.::  .|:.
pombe   616 FA---EMLARLNGI-KSTLRFESSDIIAAMKKLVLEVSATKAHSLGWEFKA--NDDHIIRQFKST 674

  Fly   719 VVNWACQYQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVYCTSIKHGSDSDWEFLWTRYK 783
            |.|:|..:.....|..||:.:..: |..|   |:.:..|:||.|:..:|::|....|:.|...|.
pombe   675 VYNYAGLFGDDKVVKDALSKFDAY-ASGN---KSAINDNLRSAVFNIAIRYGGAKSWDQLLEIYT 735

  Fly   784 KSNVAAEKRTILTALGCSREVWLLQRYLELTFDPKEAIRKQDSMWAFQAVAFNEVGFLLAKKYFM 848
            |:|....:.:.|.|.|.:.:...:|:.|:||.||  .:::||.......::.::.|.|...|:..
pombe   736 KTNDPYVRNSCLRAFGVTEDEKYIQKTLDLTLDP--IVKEQDIYLILVTLSTHKNGVLAMWKFAT 798

  Fly   849 DNVDFIYKFYHPLTKDMSRLLSPLS-------EQVIT-----LSDFNEFKDFVNNSRQSLKGLEQ 901
            .|.|          |.:|||  |::       .:.:|     .|..::.|:|.  :.:..|..|:
pombe   799 SNWD----------KLLSRL--PVAGTMRGYVVRFVTSGFTHASAIDKIKEFF--ADKDTKLYER 849

  Fly   902 AIQQTLEIMLTNVQWKERNYHQMSRSIQQ 930
            |:||:|:.:..|..:.:::...::|.:::
pombe   850 ALQQSLDTISANSSFIDKSLDDITRWLKE 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	186/464 (40%)
		ERAP1_C	582..910	CDD:463368	88/345 (26%)
ape2	NP_595998.1	M1_APN-Q_like	27..463	CDD:341064	186/465 (40%)
		ERAP1_C	541..858	CDD:463368	88/345 (26%)