Protein Alignment SP1029 and Rnpep

DIOPT Version :9

• Sequence 1: NP_001263065.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_663392.2
• Gene: Rnpep / 215615
• MGIID: 2384902
• Length: 650
• Species: Mus musculus
• Alignment Length: 622
• Identity: 145/622 - (23%)
• Similarity: 231/622 - (37%)
• Gaps: 209/622 - (33%)

  Fly   167 TQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETK-PHETLADYIWCEFQESVP 230
            ||.:....|..|||||.|..|..:...:.....:||:.:....|.: |::..       ||.|.|
Mouse   168 TQGQAVLNRAFFPCFDTPAVKCTYSALIEVPDGFTAVMSADTWEKRGPNKFF-------FQMSHP 225

  Fly   231 MSTYLVAYSVNDFSHKPSTLPNSALFRTWARPNAIDQC--DYAA-----------QFGPKVLQYY 282
            :.:||:|.::.|.: .....|.|   |.||.|..|:..  :|:.           .|||.|...|
Mouse   226 IPSYLIALAIGDLA-SAEVGPRS---RVWAEPCLIEAAKEEYSGVIEEFLATGEKLFGPYVWGRY 286

  Fly   283 EQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQRVASVVAHELAHQ 347
            :..|     :|       |.|..|.||| ..:|:....||  |...||||      |:.||::|.
Mouse   287 DLLF-----MP-------PSFPFGGMEN-PCLTFVTPCLL--AGDRSLAD------VIIHEISHS 330

  Fly   348 WFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFRRDALESS------ 406
            |||||||...|.:.||||||..|.                |..:|.:|.......||::
Mouse   331 WFGNLVTNANWGEFWLNEGFTMYA----------------QRRISTILFGAAYTCLEAATGRALL 379

  Fly   407 ----------HPISR---PIQMVSEISESFDQISYQKG-STVLRMMHLFLGEESFRSGLQAYLQK 457
                      :|:::   .|:...:..:::::..|:|| ..|..:.||...::.|...|:||:.:
Mouse   380 RQHMNVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQDQFDKFLKAYVDE 444

  Fly   458 FSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSI----MDSWTLQTGYPVINVTRDYAARTAKLN 518
            |.:    |..|.|...:...:|....|...:.||    .|.|....|:|.
Mouse   445 FKF----QSILAEDFLEFYLEYFPELKKKGVDSIPGFEFDRWLNTPGWPP--------------- 490

  Fly   519 QERYLLNTQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDL------P 577
                               ::|            :.:|         |:||.|..::|      .
Mouse   491 -------------------YLP------------DLSP---------GDSLMKPAEELAELWVTS 515

  Fly   578 GPDQWVIFNTQLST--LYKVNYDAQNWKLLIET-LTNGDFERI----HVINRAQLIDDALYLAWT 635
            .||...|....:||  .|::.|...  |:|.:: |..|:.:::    ..|:.||  :..|.|.|
Mouse   516 EPDMQAIEAVAISTWKTYQLVYFLD--KILQKSPLPPGNVKKLGETYPKISNAQ--NAELRLRW- 575

  Fly   636 GE----QDYEIAMRLIEYLQREREYLPWKSAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEH 696
            |:    .||:      |..|:.:::         |:..|:               :|..||:|..
Mouse   576 GQIILKNDYQ------EEFQKVKDF---------LQSQGK---------------QKYTLPLYHA 610

  Fly   697 LNG--------INDTFSAIPQQDQVLLKTMVVNWACQ 725
            :.|        ..|||:|...|    |.:.|||:..|
Mouse   611 MMGGSEMARTLAKDTFAATASQ----LHSNVVNYVQQ 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_001263065.1	Peptidase_M1	33..431	CDD:279741	78/296 (26%)
		M1_APN_2	43..502	CDD:189008	98/372 (26%)
		ERAP1_C	583..908	CDD:288671	37/162 (23%)
Rnpep	NP_663392.2	leuko_A4_hydro	24..634	CDD:274120	140/611 (23%)
		M1_LTA4H	24..484	CDD:189006	97/367 (26%)
		Substrate binding. /evidence=ECO:0000250	298..302		2/3 (67%)
		Leuk-A4-hydro_C	504..644	CDD:286244	40/179 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845894
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740