Protein Alignment SP1029 and R03G8.6

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_510175.1
• Gene: R03G8.6 / 181438
• WormBaseID: WBGene00011000
• Length: 747
• Species: Caenorhabditis elegans
• Alignment Length: 796
• Identity: 211/796 - (26%)
• Similarity: 350/796 - (43%)
• Gaps: 171/796 - (21%)

  Fly     5 LLFVAALGLGLATADSSADSIETTYNYYRLPTSLRPQKYHLRILTLL--------ENPEDLRFSG 61
            |:|:.|:   :....|..|:.......||||..:.|..|.:.|.|.|        ||  .:.|.|
 Worm     6 LVFILAI---IKPFASELDARIADVASYRLPRHVSPSHYDIHIKTYLPGYGWKADEN--KITFEG 65

  Fly    62 SVKILIEALENTKNVTLHSKNLTI-------DESQITLRQIGGEGKKENCVSSTAVNPSHDFYIL 119
            :|.||::..|.|..:.|||.:|.|       ||..:::.....:.:.:...          ||:.
 Worm    66 NVNILLDIKETTDKLVLHSSSLNIISATFQSDEQNVSISHWNVQTESQFLT----------FYLN 120

  Fly   120 NTCQELLAGNTYELYMPFAADLNRQLEGYYR---------SSYKDPVANLTKWISVTQFEPASAR 175
            ||.:           :..:|.:....:|..|         :|.::....:|.:  .||||...||
 Worm   121 NTVK-----------VQSSAGIQINFQGKVRTDGLGLFATNSTREDGTVMTNF--ATQFETIFAR 172

  Fly   176 LAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHETLADYIWCEFQESVPMSTYLVAYSV 240
            ...||||||:|||.:.|:|.:....||:||..|.|:|.::   |:....:::::.||:|::|..:
 Worm   173 NMIPCFDEPEFKATWNVSLEHPTGSTALSNGIEVESKVND---DWKTTTYKKTLKMSSYILALFI 234

  Fly   241 NDFSHKPSTLPNSALFRTWARPNAIDQCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSA 305
            .|...|.:.|.|....|.:..|..||:.|:|......||:.:|:.|||::|:.|:|.::|.:|..
 Worm   235 GDIQFKETILNNGVRIRVYTDPVNIDRVDHALNISRIVLEGFERQFGIRYPMEKLDFVSVQNFKF 299

  Fly   306 GAMENWGLVTYREIALLYSAAHSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATY 370
            |||||||||.:.        |:|.:.|...|..:|.||:||||||||||||:|..:|||||||:|
 Worm   300 GAMENWGLVIHN--------AYSLIGDPMDVTEIVIHEIAHQWFGNLVTMKYWDHIWLNEGFASY 356

  Fly   371 VASLGVENINPEWRSMEQESLSNLLTIFRRDALESSHPISRPI----------QMVSEISESFDQ 425
            :.|.|:..::|:               ::||....:...:..|          :.:|.:..:...
 Worm   357 MTSYGLTFLDPD---------------YQRDTFYLNCQFNPQINDGGVSLNFGKNLSSVMNNAAT 406

  Fly   426 ISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKS 490
            : |.||.:.:||:....|.|.|...::.||:|..|.|.:.::|:|:...::....:..|.:||:.
 Worm   407 V-YMKGCSFVRMLENIFGTEYFNEAIKFYLEKNQYDNVDDNDLYEAFRTSSETLDTNGKPFDIEK 470

  Fly   491 IMDSWTLQTGYPVINVTRDYAART---AKLNQERYLLNTQVARAYRGGC---WWVPLSYTTQA-- 547
            ....||.|.|:|.|.|:.|....|   :.|.:.:.:||.         |   |.:|:.|....
 Worm   471 FARCWTHQNGFPTIQVSNDNGIATLTQSHLYEPQLMLNE---------CDYKWDIPIWYQEPGEA 526

  Fly   548 -VQDFNNTAPKAWMECGKNGESLPKTIQDLPGPDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTN 611
             ||       .||:  .:|..||.....|.      ||.|......|:|.|..:.::.:.|.:..
 Worm   527 RVQ-------MAWL--NRNSTSLELVADDS------VIINANSIGYYEVLYSDKMYEKIAEQVAI 576

  Fly   612 GDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQ--REREYLPWKSAF----------- 663
             :..|..|.:..:.:.|....:..|...:..|. :|.|:.  .|.|.|..:|..
 Worm   577 -NVSRYSVNSLRRTLHDVFRYSRDGLTPFHNAF-IIAYVLVFGENEILRHESVLYLVDAVYNTNN 639

  Fly   664 ------ENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHLNGINDTFSA-----IPQ-------- 709
                  ::::.|..:|.|..:||.|.:.::             :.|||:     |||
 Worm   640 KSIVNSKDIETVKGLVNQIENFELFPKCVQ-------------SQTFSSCYQKRIPQNINLRAIM 691

  Fly   710 QDQVLLKTM--VVNWA 723
            |.::...||  :|.||
 Worm   692 QLKLSQNTMDLIVAWA 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	142/488 (29%)
		ERAP1_C	582..910	CDD:463368	36/176 (20%)
R03G8.6	NP_510175.1	M1_APN-Q_like	39..477	CDD:341064	142/489 (29%)
		ERAP1_C	548..>608	CDD:463368	11/60 (18%)