Protein Alignment SP1029 and Y42A5A.1

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_505820.1
• Gene: Y42A5A.1 / 179536
• WormBaseID: WBGene00012776
• Length: 1045
• Species: Caenorhabditis elegans
• Alignment Length: 982
• Identity: 260/982 - (26%)
• Similarity: 431/982 - (43%)
• Gaps: 178/982 - (18%)

  Fly     4 FLLFVAALGLGLATADSSADSIETTYNYYRLPTSLRPQKYHLRIL-------TLLENPEDLRFSG 61
            |.:|..:..|...|.|.....|..|.:..::|....|..|.:.:.       |:....::....|
 Worm   123 FPIFTNSTELITTTEDPLYVHINNTNHRLQIPQIHIPLLYEVELKLFVPWRPTISFGSDNFSVKG 187

  Fly    62 SVKILIEALENTKNVTLHSKN-------LTIDE--SQITLRQIGGEGKKENCVSSTAVNPSHDFY 117
            .|::...:...:: :.|||.:       :..||  ..||::.:|.:..:              ..
 Worm   188 HVRVHFTSGGGSR-ILLHSDSKQHIGDCVVRDELNRNITVKLVGRQYSQ--------------IL 237

  Fly   118 ILNTCQELLAGNTYELYMPFAADLNRQLE-GYYRSSYKDPVANLTKWISVTQFEPASARLAFPCF 181
            .||...:::.|..|.|.:.|.:.:|..|. |.:.:.|  ...|.|:::..||.:.:.||..|||.
 Worm   238 DLNLETDMIHGMNYTLDVAFKSAINLNLAYGLFAAPY--TFENETRYVVATQLQISEARTVFPCI 300

  Fly   182 DEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHETLADYIW--CEFQESVPMSTYLVAYSVNDFS 244
            |.||.||.|...:.:....|:|:||.|..||     .|..|  ..|..:.||||||.|:||:|:.
 Worm   301 DVPDMKAQFDTVIIHPTGTTSIANMMENSTK-----VDGEWTTTTFHRTPPMSTYLFAFSVSDYP 360

  Fly   245 HKPSTLPNSALFRTWARP-NAIDQCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAM 308
            :..:........|.:..| ..:|........|| ||.:||.:|||.:||.|:|.:.||..|..||
 Worm   361 YLETFSGRGVRSRVYCDPTKLVDAQLITKSIGP-VLDFYEDYFGIPYPLEKLDVVIVPALSVTAM 424

  Fly   309 ENWGLVTYREIALLYSAAHSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVAS 373
            |||||:|.|:...||:....:::.|..|..:|||||||||||||||||||.||||||||||.::.
 Worm   425 ENWGLITIRQTNGLYTEGRFAISQKHDVQEIVAHELAHQWFGNLVTMKWWNDLWLNEGFATLISV 489

  Fly   374 LGVENI-NPEWRSMEQESLSNLLTIFRRDALESSHPISRPIQMVSEISESFDQ--------ISYQ 429
            ..|:.: |..|| .|..|..:.....|.|.::|..|:|      .:.:.:||.        |.|:
 Worm   490 RAVDFLENTTWR-YEDSSAESQCVALRADQIDSISPVS------GKKNSNFDSYMEIQGKAIIYK 547

  Fly   430 KGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNLWESL-----TQAAHKYRSLPKSYDIK 489
            |.:.::||:...:.|:.||.||:.:|..|.||||:.::|:..|     :.|....|.  :::.:.
 Worm   548 KSAIIIRMIERLVEEDIFRQGLKRFLNTFLYKNADHEDLFNVLVYVHDSSAGGHLRG--QNFSLS 610

  Fly   490 SIMDSWTLQTGYPVINVTRDYAARTAKLNQERYLLNTQVAR-AYRGGCWWVPLSYT-----TQAV 548
            .:||:|..|..:|||:|.|...: ...|.||:|   ..|.| ......|.:|:.|.     ...|
 Worm   611 DVMDTWIRQAHFPVIHVNRKEGS-LVTLRQEKY---EHVPRDEPEKQVWKIPIFYDDPVSGKHKV 671

  Fly   549 QDFNNTAPKAWMECGKNGESLPKTIQDLPGPDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGD 613
            ....:|.||.:               |:.|   .::.:....|..::.||.:.:..:...|.: |
 Worm   672 FWLTDTQPKVF---------------DMGG---LLVVDPHQLTYMRLRYDMEMYSDITMALMD-D 717

  Fly   614 FERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQREREYLPWK--SAFENLKRVGRIVRQT 676
            |..|...:|::||||.|.:|..|:..|::...|..|:.||..|.|::  ||:.:.......:.:
 Worm   718 FTMIPTNSRSRLIDDTLAMAENGQLTYKVPFNLTMYMSREIAYRPFQTFSAYLDFFLPRMYIHE- 781

  Fly   677 PDFEFFKRYMKKLILPIYEHLN--GINDTFSAIPQQDQVLLKTMVVNWACQYQVGDCVPQALAYY 739
             .:..:|:|::.::...::..|  |::.:|.  ...|....:.:||..||..:...||..|...:
 Worm   782 -GWSIYKKYLELVVGIPFDKFNAEGLDVSFD--HNTDLFHTRQIVVFRACGIEYEPCVRMAKQRF 843

  Fly   740 RNWRAEANPD-------EKNPVPINVRSTVYCTSIKHGSDSDWEFLWTRYKKSNVAAEKRTILTA 797
            ...|...:.:       |.|.:|..:|..||..:|..|:..|::||:.::...:...|...|.|.
 Worm   844 AELRVNCSGENQLLSGMECNKIPYYLRPHVYSAAINDGTQEDFDFLYKKWMIEHYMMEHDNIFTG 908

  Fly   798 LGCSREVWLLQRYLELTFDPKEAIRKQDSMWAFQAVAFNEV-------GFLLAKKYFMDN--VDF 853
            | |:..:                  :::|..|::.|..|..       ..|.:||...:|  :|.
 Worm   909 L-CTTNI------------------RENSDRAWRQVIKNGARENVMVRAQLCSKKLSKNNFILDL 954

  Fly   854 IY--KFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQSLKGLEQAIQQTLEIMLTNVQW 916
            :|  |.|                          .|:||:..|:||..|:|.:            :
 Worm   955 LYEDKVY--------------------------LKEFVDKDRKSLFALQQLL------------Y 981

  Fly   917 KERNYHQ 923
            ::.||.:
 Worm   982 RKINYEE 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	154/488 (32%)
		ERAP1_C	582..910	CDD:463368	74/349 (21%)
Y42A5A.1	NP_505820.1	M1_APN-Q_like	160..618	CDD:341064	154/489 (31%)
		ERAP1_C	687..>939	CDD:463368	58/275 (21%)